{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"O68687","uniProtkbId":"GERPE_BACCE","entryAudit":{"firstPublicDate":"2002-07-26","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1998-08-01","entryVersion":57,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Bacillus cereus","taxonId":1396,"lineage":["Bacteria","Bacillati","Bacillota","Bacilli","Caryophanales","Bacillaceae","Bacillus","Bacillus cereus group"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Probable spore germination protein GerPE"}}},"genes":[{"geneName":{"value":"gerPE"}}],"comments":[{"texts":[{"value":"Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor"}],"commentType":"FUNCTION"},{"texts":[{"value":"Expressed during sporulation, around the time of spore coat synthesis and assembly, in mother cell compartment"}],"commentType":"DEVELOPMENTAL STAGE"},{"texts":[{"value":"Expression is sigma K-dependent and negatively regulated by GerE"}],"commentType":"INDUCTION"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":128,"modifier":"EXACT"}},"description":"Probable spore germination protein GerPE","featureId":"PRO_0000087474"}],"keywords":[{"id":"KW-0309","category":"Biological process","name":"Germination"},{"id":"KW-0749","category":"Biological process","name":"Sporulation"}],"references":[{"referenceNumber":1,"citation":{"id":"10715007","citationType":"journal article","authors":["Behravan J.","Chirakkal H.","Masson A.","Moir A."],"citationCrossReferences":[{"database":"PubMed","id":"10715007"},{"database":"DOI","id":"10.1128/jb.182.7.1987-1994.2000"}],"title":"Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus affect access of germinants to their targets in spores.","publicationDate":"2000","journal":"J. Bacteriol.","firstPage":"1987","lastPage":"1994","volume":"182"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]","CHARACTERIZATION"],"referenceComments":[{"value":"ATCC 10876 / DSM 9378 / NRRL B-569","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF053927","properties":[{"key":"ProteinId","value":"AAC08016.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_000902319.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_AP043895.1"}]},{"database":"AlphaFoldDB","id":"O68687","properties":[{"key":"Description","value":"-"}]},{"database":"InterPro","id":"IPR024496","properties":[{"key":"EntryName","value":"Spore_germ_GerPE"}]},{"database":"Pfam","id":"PF10970","properties":[{"key":"EntryName","value":"GerPE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MLHHVSIVQNVSIISLGIAAVFQVGDANQMELKSRAIAVHREIPFYIRGEGRFDAFEIFTDEHITIPKRTTDVKLNIVNECPFIEVNNVELRTLLNSGCFQIGNVDYGFNNSRIIQIRQYITDEPSAQ","length":128,"molWeight":14535,"crc64":"96CF5F37633DCE8C","md5":"1F728C42FE98971584A65E6D21FF5E1C"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"DEVELOPMENTAL STAGE":1,"INDUCTION":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI000012B3C4"}}