{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"O59008","uniProtkbId":"Y1297_PYRHO","entryAudit":{"firstPublicDate":"2004-10-11","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"1998-08-01","entryVersion":86,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)","taxonId":70601,"lineage":["Archaea","Methanobacteriati","Methanobacteriota","Thermococci","Thermococcales","Thermococcaceae","Pyrococcus"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"UPF0332 protein PH1297"}}},"genes":[{"orderedLocusNames":[{"value":"PH1297"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the UPF0332 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":142,"modifier":"EXACT"}},"description":"UPF0332 protein PH1297","featureId":"PRO_0000159641"}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"9679194","citationType":"journal article","authors":["Kawarabayasi Y.","Sawada M.","Horikawa H.","Haikawa Y.","Hino Y.","Yamamoto S.","Sekine M.","Baba S.","Kosugi H.","Hosoyama A.","Nagai Y.","Sakai M.","Ogura K.","Otsuka R.","Nakazawa H.","Takamiya M.","Ohfuku Y.","Funahashi T.","Tanaka T.","Kudoh Y.","Yamazaki J.","Kushida N.","Oguchi A.","Aoki K.","Yoshizawa T.","Nakamura Y.","Robb F.T.","Horikoshi K.","Masuchi Y.","Shizuya H.","Kikuchi H."],"citationCrossReferences":[{"database":"PubMed","id":"9679194"},{"database":"DOI","id":"10.1093/dnares/5.2.55"}],"title":"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.","publicationDate":"1998","journal":"DNA Res.","firstPage":"55","lastPage":"76","volume":"5"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"BA000001","properties":[{"key":"ProteinId","value":"BAA30401.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"A71000","properties":[{"key":"EntryName","value":"A71000"}]},{"database":"RefSeq","id":"WP_010885384.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000961.1"}]},{"database":"AlphaFoldDB","id":"O59008","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"O59008","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"BAA30401","properties":[{"key":"ProteinId","value":"BAA30401"},{"key":"GeneId","value":"BAA30401"}]},{"database":"GeneID","id":"1443620","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"pho:PH1297","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"arCOG02123","properties":[{"key":"ToxonomicScope","value":"Archaea"}]},{"database":"Proteomes","id":"UP000000752","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"Gene3D","id":"1.20.120.330","properties":[{"key":"EntryName","value":"Nucleotidyltransferases domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR007842","properties":[{"key":"EntryName","value":"HEPN_dom"}]},{"database":"InterPro","id":"IPR052226","properties":[{"key":"EntryName","value":"UPF0332_toxin"}]},{"database":"PANTHER","id":"PTHR36565:SF5","properties":[{"key":"EntryName","value":"TOXIN MJ0605-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR36565","properties":[{"key":"EntryName","value":"UPF0332 PROTEIN TM_1000"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF05168","properties":[{"key":"EntryName","value":"HEPN"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDVPEEVEKHIKITEEELSSAYLLLENGKLRDSISRAYYSMFHAAKALLLLKGIDPRKHSGVIRMFGLHFVNSGFIERVYAKYLTHSRSDQRLTMMSITNQVMRKLKTLLKVLSASWRELKVFWRRLKMDKKAQALNEFLKL","length":142,"molWeight":16673,"crc64":"B42B46D83229ACB0","md5":"8F2792561BFAE8A1BCB7D5C4C252AD59"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI000006303D"}}