{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"O55708","uniProtkbId":"VF067_IIV6","entryAudit":{"firstPublicDate":"2009-06-16","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1998-06-01","entryVersion":61,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Invertebrate iridescent virus 6","commonName":"IIV-6","synonyms":["Chilo iridescent virus"],"taxonId":176652,"lineage":["Viruses","Varidnaviria","Bamfordvirae","Nucleocytoviricota","Megaviricetes","Pimascovirales","Pimascovirales incertae sedis","Iridoviridae","Betairidovirinae","Iridovirus","Iridovirus chilo1"]},"organismHosts":[{"scientificName":"Acheta domesticus","commonName":"House cricket","taxonId":6997},{"scientificName":"Chilo suppressalis","commonName":"Asiatic rice borer moth","taxonId":168631},{"scientificName":"Gryllus bimaculatus","commonName":"Two-spotted cricket","taxonId":6999},{"scientificName":"Gryllus campestris","taxonId":58607},{"scientificName":"Spodoptera frugiperda","commonName":"Fall armyworm","taxonId":7108}],"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein 067R"}}},"genes":[{"orfNames":[{"value":"IIV6-067R"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the IIV-6 067R family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":456,"modifier":"EXACT"}},"description":"Uncharacterized protein 067R","featureId":"PRO_0000377761"},{"type":"Transmembrane","location":{"start":{"value":347,"modifier":"EXACT"},"end":{"value":365,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Region","location":{"start":{"value":181,"modifier":"EXACT"},"end":{"value":231,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":383,"modifier":"EXACT"},"end":{"value":456,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Coiled coil","location":{"start":{"value":216,"modifier":"EXACT"},"end":{"value":248,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Compositional bias","location":{"start":{"value":181,"modifier":"EXACT"},"end":{"value":210,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":217,"modifier":"EXACT"},"end":{"value":231,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":383,"modifier":"EXACT"},"end":{"value":407,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":441,"modifier":"EXACT"},"end":{"value":456,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"11448171","citationType":"journal article","authors":["Jakob N.J.","Mueller K.","Bahr U.","Darai G."],"citationCrossReferences":[{"database":"PubMed","id":"11448171"},{"database":"DOI","id":"10.1006/viro.2001.0963"}],"title":"Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus.","publicationDate":"2001","journal":"Virology","firstPage":"182","lastPage":"196","volume":"286"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":2,"citation":{"id":"17239238","citationType":"journal article","authors":["Eaton H.E.","Metcalf J.","Penny E.","Tcherepanov V.","Upton C.","Brunetti C.R."],"citationCrossReferences":[{"database":"PubMed","id":"17239238"},{"database":"DOI","id":"10.1186/1743-422x-4-11"}],"title":"Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes.","publicationDate":"2007","journal":"Virol. J.","firstPage":"11","lastPage":"11","volume":"4"},"referencePositions":["GENOME REANNOTATION"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF303741","properties":[{"key":"ProteinId","value":"AAB94419.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"T03045","properties":[{"key":"EntryName","value":"T03045"}]},{"database":"RefSeq","id":"NP_149530.1","properties":[{"key":"NucleotideSequenceId","value":"NC_003038.1"}]},{"database":"AlphaFoldDB","id":"O55708","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"1733049","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"vg:1733049","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"10549at10239","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001359","properties":[{"key":"Component","value":"Segment"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"InterPro","id":"IPR043910","properties":[{"key":"EntryName","value":"DUF5767"}]},{"database":"Pfam","id":"PF19071","properties":[{"key":"EntryName","value":"DUF5767"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKTIIIRKIPPIDDFKRFVPKRFSRFPQLYLELLENKNKVKLNCIGKEFVPTTPPLSTGRETIVSKDPHVVQSSISNTPIRTEIKDTPRYEETPIKRTITVTNVKTVKSSSISGMNGRNRLYDDDLFDDDRYKSPTTRKFQGEKRDEDIRLIPKSSNIGSSKYKPVLTRVEENENKKIHIDQRKESIVNDERKKNPEFREKPDKNEDKKVKPPPSLKEIENKGIDHEENEEDKKRELMFKLQLLQKQYPLRDIPDFTIRSEYKSMKKTYDIIVKQLSVDSSVETYKNYLVGGFMVCEMVFGRIGFDMEGFTQQQLLSMNSYEKLLLELGEKTYTPAGMDKWPVEVRLALAILFNAVWFIAAKMIMKKTKINILSLFNNTKGLNKSGTTPNSVSPRTWGNSKSPQSEFNFIGRKNENNSVGRTQMKGPSINRIDEGFGSESDESRREMREQGIETLK","length":456,"molWeight":52816,"crc64":"290CD897A855B798","md5":"992EEEAE6032968AE5CC31C7BB21475B"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Transmembrane":1,"Region":2,"Coiled coil":1,"Compositional bias":4},"uniParcId":"UPI00000F91E6"}}