{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"O23341","uniProtkbId":"OFP11_ARATH","entryAudit":{"firstPublicDate":"2014-07-09","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1998-01-01","entryVersion":131,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Arabidopsis thaliana","commonName":"Mouse-ear cress","taxonId":3702,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Camelineae","Arabidopsis"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"value":"Transcription repressor OFP11"}},"alternativeNames":[{"fullName":{"value":"Ovate family protein 11"},"shortNames":[{"value":"AtOFP11"}]}]},"genes":[{"geneName":{"value":"OFP11"},"orderedLocusNames":[{"value":"At4g14860"}],"orfNames":[{"value":"dl3470w"},{"value":"FCAALL.337"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"21886836"}],"value":"Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors"}],"commentType":"FUNCTION"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"21886836"}],"value":"Expressed in roots, rosette and cauline leaves, shoots, stems, flower buds and siliques"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"21886836"}],"value":"Plants over-expressing OFP11 have no visible phenotype"}],"commentType":"MISCELLANEOUS"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":182,"modifier":"EXACT"}},"description":"Transcription repressor OFP11","featureId":"PRO_0000429680"},{"type":"Domain","location":{"start":{"value":104,"modifier":"EXACT"},"end":{"value":169,"modifier":"EXACT"}},"description":"OVATE","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU01090"}]},{"type":"Region","location":{"start":{"value":62,"modifier":"EXACT"},"end":{"value":94,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0678","category":"Molecular function","name":"Repressor"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"9461215","citationType":"journal article","authors":["Bevan M.","Bancroft I.","Bent E.","Love K.","Goodman H.M.","Dean C.","Bergkamp R.","Dirkse W.","van Staveren M.","Stiekema W.","Drost L.","Ridley P.","Hudson S.-A.","Patel K.","Murphy G.","Piffanelli P.","Wedler H.","Wedler E.","Wambutt R.","Weitzenegger T.","Pohl T.","Terryn N.","Gielen J.","Villarroel R.","De Clercq R.","van Montagu M.","Lecharny A.","Aubourg S.","Gy I.","Kreis M.","Lao N.","Kavanagh T.","Hempel S.","Kotter P.","Entian K.-D.","Rieger M.","Schaefer M.","Funk B.","Mueller-Auer S.","Silvey M.","James R.","Monfort A.","Pons A.","Puigdomenech P.","Douka A.","Voukelatou E.","Milioni D.","Hatzopoulos P.","Piravandi E.","Obermaier B.","Hilbert H.","Duesterhoeft A.","Moores T.","Jones J.D.G.","Eneva T.","Palme K.","Benes V.","Rechmann S.","Ansorge W.","Cooke R.","Berger C.","Delseny M.","Voet M.","Volckaert G.","Mewes H.-W.","Klosterman S.","Schueller C.","Chalwatzis N."],"citationCrossReferences":[{"database":"PubMed","id":"9461215"},{"database":"DOI","id":"10.1038/35140"}],"title":"Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana.","publicationDate":"1998","journal":"Nature","firstPage":"485","lastPage":"488","volume":"391"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"10617198","citationType":"journal article","authors":["Mayer K.F.X.","Schueller C.","Wambutt R.","Murphy G.","Volckaert G.","Pohl T.","Duesterhoeft A.","Stiekema W.","Entian K.-D.","Terryn N.","Harris B.","Ansorge W.","Brandt P.","Grivell L.A.","Rieger M.","Weichselgartner M.","de Simone V.","Obermaier B.","Mache R.","Mueller M.","Kreis M.","Delseny M.","Puigdomenech P.","Watson M.","Schmidtheini T.","Reichert B.","Portetelle D.","Perez-Alonso M.","Boutry M.","Bancroft I.","Vos P.","Hoheisel J.","Zimmermann W.","Wedler H.","Ridley P.","Langham S.-A.","McCullagh B.","Bilham L.","Robben J.","van der Schueren J.","Grymonprez B.","Chuang Y.-J.","Vandenbussche F.","Braeken M.","Weltjens I.","Voet M.","Bastiaens I.","Aert R.","Defoor E.","Weitzenegger T.","Bothe G.","Ramsperger U.","Hilbert H.","Braun M.","Holzer E.","Brandt A.","Peters S.","van Staveren M.","Dirkse W.","Mooijman P.","Klein Lankhorst R.","Rose M.","Hauf J.","Koetter P.","Berneiser S.","Hempel S.","Feldpausch M.","Lamberth S.","Van den Daele H.","De Keyser A.","Buysshaert C.","Gielen J.","Villarroel R.","De Clercq R.","van Montagu M.","Rogers J.","Cronin A.","Quail M.A.","Bray-Allen S.","Clark L.","Doggett J.","Hall S.","Kay M.","Lennard N.","McLay K.","Mayes R.","Pettett A.","Rajandream M.A.","Lyne M.","Benes V.","Rechmann S.","Borkova D.","Bloecker H.","Scharfe M.","Grimm M.","Loehnert T.-H.","Dose S.","de Haan M.","Maarse A.C.","Schaefer M.","Mueller-Auer S.","Gabel C.","Fuchs M.","Fartmann B.","Granderath K.","Dauner D.","Herzl A.","Neumann S.","Argiriou A.","Vitale D.","Liguori R.","Piravandi E.","Massenet O.","Quigley F.","Clabauld G.","Muendlein A.","Felber R.","Schnabl S.","Hiller R.","Schmidt W.","Lecharny A.","Aubourg S.","Chefdor F.","Cooke R.","Berger C.","Monfort A.","Casacuberta E.","Gibbons T.","Weber N.","Vandenbol M.","Bargues M.","Terol J.","Torres A.","Perez-Perez A.","Purnelle B.","Bent E.","Johnson S.","Tacon D.","Jesse T.","Heijnen L.","Schwarz S.","Scholler P.","Heber S.","Francs P.","Bielke C.","Frishman D.","Haase D.","Lemcke K.","Mewes H.-W.","Stocker S.","Zaccaria P.","Bevan M.","Wilson R.K.","de la Bastide M.","Habermann K.","Parnell L.","Dedhia N.","Gnoj L.","Schutz K.","Huang E.","Spiegel L.","Sekhon M.","Murray J.","Sheet P.","Cordes M.","Abu-Threideh J.","Stoneking T.","Kalicki J.","Graves T.","Harmon G.","Edwards J.","Latreille P.","Courtney L.","Cloud J.","Abbott A.","Scott K.","Johnson D.","Minx P.","Bentley D.","Fulton B.","Miller N.","Greco T.","Kemp K.","Kramer J.","Fulton L.","Mardis E.","Dante M.","Pepin K.","Hillier L.W.","Nelson J.","Spieth J.","Ryan E.","Andrews S.","Geisel C.","Layman D.","Du H.","Ali J.","Berghoff A.","Jones K.","Drone K.","Cotton M.","Joshu C.","Antonoiu B.","Zidanic M.","Strong C.","Sun H.","Lamar B.","Yordan C.","Ma P.","Zhong J.","Preston R.","Vil D.","Shekher M.","Matero A.","Shah R.","Swaby I.K.","O'Shaughnessy A.","Rodriguez M.","Hoffman J.","Till S.","Granat S.","Shohdy N.","Hasegawa A.","Hameed A.","Lodhi M.","Johnson A.","Chen E.","Marra M.A.","Martienssen R.","McCombie W.R."],"citationCrossReferences":[{"database":"PubMed","id":"10617198"},{"database":"DOI","id":"10.1038/47134"}],"title":"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.","publicationDate":"1999","journal":"Nature","firstPage":"769","lastPage":"777","volume":"402"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"27862469","citationType":"journal article","authors":["Cheng C.Y.","Krishnakumar V.","Chan A.P.","Thibaud-Nissen F.","Schobel S.","Town C.D."],"citationCrossReferences":[{"database":"PubMed","id":"27862469"},{"database":"DOI","id":"10.1111/tpj.13415"}],"title":"Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.","publicationDate":"2017","journal":"Plant J.","firstPage":"789","lastPage":"804","volume":"89"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"CI-CI4AM1G71UC0S","citationType":"submission","authoringGroup":["The Arabidopsis Information Resource (TAIR)"],"title":"Community-consensus reference genome of Arabidopsis thaliana Col-0.","publicationDate":"FEB-2026","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"21886836","citationType":"journal article","authors":["Wang S.","Chang Y.","Guo J.","Zeng Q.","Ellis B.E.","Chen J.G."],"citationCrossReferences":[{"database":"PubMed","id":"21886836"},{"database":"DOI","id":"10.1371/journal.pone.0023896"}],"title":"Arabidopsis ovate family proteins, a novel transcriptional repressor family, control multiple aspects of plant growth and development.","publicationDate":"2011","journal":"PLoS ONE","firstPage":"E23896","lastPage":"E23896","volume":"6"},"referencePositions":["FUNCTION","TISSUE SPECIFICITY","GENE FAMILY"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Z97337","properties":[{"key":"ProteinId","value":"CAB10265.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL161540","properties":[{"key":"ProteinId","value":"CAB78528.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002687","properties":[{"key":"ProteinId","value":"AEE83510.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408686","properties":[{"key":"ProteinId","value":"CAO7047222.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"G71411","properties":[{"key":"EntryName","value":"G71411"}]},{"database":"RefSeq","id":"NP_193222.1","properties":[{"key":"NucleotideSequenceId","value":"NM_117572.2"}]},{"database":"AlphaFoldDB","id":"O23341","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"3702.O23341","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"3702-O23341","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"827143","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT4G14860","properties":[{"key":"Description","value":"-"}]},{"database":"Araport","id":"AT4G14860","properties":[{"key":"Description","value":"-"}]},{"database":"TAIR","id":"AT4G14860","properties":[{"key":"GeneName","value":"OFP11"}]},{"database":"eggNOG","id":"ENOG502S0CD","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_069722_1_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"O23341","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"NHNSQCP","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"PhylomeDB","id":"O23341","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:O23341","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000006548","properties":[{"key":"Component","value":"Chromosome 4"}]},{"database":"ExpressionAtlas","id":"O23341","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0045892","properties":[{"key":"GoTerm","value":"P:negative regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"21886836"}]},{"database":"InterPro","id":"IPR038933","properties":[{"key":"EntryName","value":"Ovate"}]},{"database":"InterPro","id":"IPR006458","properties":[{"key":"EntryName","value":"Ovate_C"}]},{"database":"NCBIfam","id":"TIGR01568","properties":[{"key":"EntryName","value":"A_thal_3678"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33057:SF196","properties":[{"key":"EntryName","value":"TRANSCRIPTION REPRESSOR OFP11"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33057","properties":[{"key":"EntryName","value":"TRANSCRIPTION REPRESSOR OFP7-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF04844","properties":[{"key":"EntryName","value":"Ovate"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51754","properties":[{"key":"EntryName","value":"OVATE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSNFLRKKLHLCFSSSGGLSPSIPSSPIIVSNHNAQSHPHHTPSIFINNFNSLYDQLSVSSPLHRRHSSENPAGVFSTNRREEEEEDETTTSVSKLLSGGTAIMKHIESPDPYRDFGRSMREMVEARDLTRDVVADREYLHELLFCYLYLNPKHTHRFIVSAFADTLLWLLSPSPSPEHFLS","length":182,"molWeight":20678,"crc64":"B25688903F28310E","md5":"1063E74F31A1F4275EE7B52A7DD1E2B2"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBCELLULAR LOCATION":1,"TISSUE SPECIFICITY":1,"MISCELLANEOUS":1},"countByFeatureType":{"Chain":1,"Domain":1,"Region":1},"uniParcId":"UPI00000A8A7B"}}