{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"O06720","uniProtkbId":"GERPB_BACSU","entryAudit":{"firstPublicDate":"2002-07-26","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2002-07-26","entryVersion":107,"sequenceVersion":3},"annotationScore":2.0,"organism":{"scientificName":"Bacillus subtilis (strain 168)","taxonId":224308,"lineage":["Bacteria","Bacillati","Bacillota","Bacilli","Caryophanales","Bacillaceae","Bacillus"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Probable spore germination protein GerPB"}}},"genes":[{"geneName":{"value":"gerPB"},"synonyms":[{"value":"yisG"}],"orderedLocusNames":[{"value":"BSU10710"}]}],"comments":[{"texts":[{"value":"Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor"}],"commentType":"FUNCTION"},{"texts":[{"value":"Expressed during sporulation, around the time of spore coat synthesis and assembly, in mother cell compartment"}],"commentType":"DEVELOPMENTAL STAGE"},{"texts":[{"value":"Expression is sigma K-dependent and negatively regulated by GerE"}],"commentType":"INDUCTION"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":77,"modifier":"EXACT"}},"description":"Probable spore germination protein GerPB","featureId":"PRO_0000087468"},{"type":"Region","location":{"start":{"value":48,"modifier":"EXACT"},"end":{"value":77,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":54,"modifier":"EXACT"},"end":{"value":65,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-0309","category":"Biological process","name":"Germination"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0749","category":"Biological process","name":"Sporulation"}],"references":[{"referenceNumber":1,"citation":{"id":"9353931","citationType":"journal article","authors":["Medina N.","Vannier F.","Roche B.","Autret S.","Levine A.","Seror S.J."],"citationCrossReferences":[{"database":"PubMed","id":"9353931"},{"database":"DOI","id":"10.1099/00221287-143-10-3305"}],"title":"Sequencing of regions downstream of addA (98 degrees) and citG (289 degrees) in Bacillus subtilis.","publicationDate":"1997","journal":"Microbiology","firstPage":"3305","lastPage":"3308","volume":"143"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"168","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9384377","citationType":"journal article","authors":["Kunst F.","Ogasawara N.","Moszer I.","Albertini A.M.","Alloni G.","Azevedo V.","Bertero M.G.","Bessieres P.","Bolotin A.","Borchert S.","Borriss R.","Boursier L.","Brans A.","Braun M.","Brignell S.C.","Bron S.","Brouillet S.","Bruschi C.V.","Caldwell B.","Capuano V.","Carter N.M.","Choi S.-K.","Codani J.-J.","Connerton I.F.","Cummings N.J.","Daniel R.A.","Denizot F.","Devine K.M.","Duesterhoeft A.","Ehrlich S.D.","Emmerson P.T.","Entian K.-D.","Errington J.","Fabret C.","Ferrari E.","Foulger D.","Fritz C.","Fujita M.","Fujita Y.","Fuma S.","Galizzi A.","Galleron N.","Ghim S.-Y.","Glaser P.","Goffeau A.","Golightly E.J.","Grandi G.","Guiseppi G.","Guy B.J.","Haga K.","Haiech J.","Harwood C.R.","Henaut A.","Hilbert H.","Holsappel S.","Hosono S.","Hullo M.-F.","Itaya M.","Jones L.-M.","Joris B.","Karamata D.","Kasahara Y.","Klaerr-Blanchard M.","Klein C.","Kobayashi Y.","Koetter P.","Koningstein G.","Krogh S.","Kumano M.","Kurita K.","Lapidus A.","Lardinois S.","Lauber J.","Lazarevic V.","Lee S.-M.","Levine A.","Liu H.","Masuda S.","Mauel C.","Medigue C.","Medina N.","Mellado R.P.","Mizuno M.","Moestl D.","Nakai S.","Noback M.","Noone D.","O'Reilly M.","Ogawa K.","Ogiwara A.","Oudega B.","Park S.-H.","Parro V.","Pohl T.M.","Portetelle D.","Porwollik S.","Prescott A.M.","Presecan E.","Pujic P.","Purnelle B.","Rapoport G.","Rey M.","Reynolds S.","Rieger M.","Rivolta C.","Rocha E.","Roche B.","Rose M.","Sadaie Y.","Sato T.","Scanlan E.","Schleich S.","Schroeter R.","Scoffone F.","Sekiguchi J.","Sekowska A.","Seror S.J.","Serror P.","Shin B.-S.","Soldo B.","Sorokin A.","Tacconi E.","Takagi T.","Takahashi H.","Takemaru K.","Takeuchi M.","Tamakoshi A.","Tanaka T.","Terpstra P.","Tognoni A.","Tosato V.","Uchiyama S.","Vandenbol M.","Vannier F.","Vassarotti A.","Viari A.","Wambutt R.","Wedler E.","Wedler H.","Weitzenegger T.","Winters P.","Wipat A.","Yamamoto H.","Yamane K.","Yasumoto K.","Yata K.","Yoshida K.","Yoshikawa H.-F.","Zumstein E.","Yoshikawa H.","Danchin A."],"citationCrossReferences":[{"database":"PubMed","id":"9384377"},{"database":"DOI","id":"10.1038/36786"}],"title":"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.","publicationDate":"1997","journal":"Nature","firstPage":"249","lastPage":"256","volume":"390"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"168","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"10715007","citationType":"journal article","authors":["Behravan J.","Chirakkal H.","Masson A.","Moir A."],"citationCrossReferences":[{"database":"PubMed","id":"10715007"},{"database":"DOI","id":"10.1128/jb.182.7.1987-1994.2000"}],"title":"Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus affect access of germinants to their targets in spores.","publicationDate":"2000","journal":"J. Bacteriol.","firstPage":"1987","lastPage":"1994","volume":"182"},"referencePositions":["CHARACTERIZATION"],"referenceComments":[{"value":"168 / 1604","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Y09476","properties":[{"key":"ProteinId","value":"CAA70678.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL009126","properties":[{"key":"ProteinId","value":"CAB12911.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"G69836","properties":[{"key":"EntryName","value":"G69836"}]},{"database":"RefSeq","id":"NP_388952.2","properties":[{"key":"NucleotideSequenceId","value":"NC_000964.3"}]},{"database":"RefSeq","id":"WP_003233090.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000964.3"}]},{"database":"AlphaFoldDB","id":"O06720","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"O06720","properties":[{"key":"Number of interactors","value":"31"}]},{"database":"STRING","id":"224308.BSU10710","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"224308-BSU10710","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"CAB12911","properties":[{"key":"ProteinId","value":"CAB12911"},{"key":"GeneId","value":"BSU_10710"}]},{"database":"GeneID","id":"939781","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"bsu:BSU10710","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|224308.179.peg.1151","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"eggNOG","id":"ENOG50335HY","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"InParanoid","id":"O06720","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"2971631at2","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"BSUB:BSU10710-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001570","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"AbasyAtlas","id":"O06720","properties":[{"key":"Description","value":"-"}]},{"database":"InterPro","id":"IPR024255","properties":[{"key":"EntryName","value":"GerPB"}]},{"database":"Pfam","id":"PF10803","properties":[{"key":"EntryName","value":"GerPB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MNFYINQTIQINYLRLESISNSSILQIGSAGSIKSLSNLYNTGSYVEPAPEVSGSGQPLQLQEPDTGSLVPLQPPGR","length":77,"molWeight":8280,"crc64":"5A8A8E71836ADC34","md5":"FD7F174D95521F5E7572B1B37B395910"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"DEVELOPMENTAL STAGE":1,"INDUCTION":1},"countByFeatureType":{"Chain":1,"Region":1,"Compositional bias":1},"uniParcId":"UPI000012B3C1"}}