{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"H3BNL8","uniProtkbId":"ARMD2_HUMAN","entryAudit":{"firstPublicDate":"2014-02-19","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2012-04-18","entryVersion":69,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Armadillo-like helical domain-containing protein 2"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:49394"}],"value":"ARMH2"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:49394"}],"value":"C6orf229"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":230,"modifier":"EXACT"}},"description":"Armadillo-like helical domain-containing protein 2","featureId":"PRO_0000425554"}],"keywords":[{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"14574404","citationType":"journal article","authors":["Mungall A.J.","Palmer S.A.","Sims S.K.","Edwards C.A.","Ashurst J.L.","Wilming L.","Jones M.C.","Horton R.","Hunt S.E.","Scott C.E.","Gilbert J.G.R.","Clamp M.E.","Bethel G.","Milne S.","Ainscough R.","Almeida J.P.","Ambrose K.D.","Andrews T.D.","Ashwell R.I.S.","Babbage A.K.","Bagguley C.L.","Bailey J.","Banerjee R.","Barker D.J.","Barlow K.F.","Bates K.","Beare D.M.","Beasley H.","Beasley O.","Bird C.P.","Blakey S.E.","Bray-Allen S.","Brook J.","Brown A.J.","Brown J.Y.","Burford D.C.","Burrill W.","Burton J.","Carder C.","Carter N.P.","Chapman J.C.","Clark S.Y.","Clark G.","Clee C.M.","Clegg S.","Cobley V.","Collier R.E.","Collins J.E.","Colman L.K.","Corby N.R.","Coville G.J.","Culley K.M.","Dhami P.","Davies J.","Dunn M.","Earthrowl M.E.","Ellington A.E.","Evans K.A.","Faulkner L.","Francis M.D.","Frankish A.","Frankland J.","French L.","Garner P.","Garnett J.","Ghori M.J.","Gilby L.M.","Gillson C.J.","Glithero R.J.","Grafham D.V.","Grant M.","Gribble S.","Griffiths C.","Griffiths M.N.D.","Hall R.","Halls K.S.","Hammond S.","Harley J.L.","Hart E.A.","Heath P.D.","Heathcott R.","Holmes S.J.","Howden P.J.","Howe K.L.","Howell G.R.","Huckle E.","Humphray S.J.","Humphries M.D.","Hunt A.R.","Johnson C.M.","Joy A.A.","Kay M.","Keenan S.J.","Kimberley A.M.","King A.","Laird G.K.","Langford C.","Lawlor S.","Leongamornlert D.A.","Leversha M.","Lloyd C.R.","Lloyd D.M.","Loveland J.E.","Lovell J.","Martin S.","Mashreghi-Mohammadi M.","Maslen G.L.","Matthews L.","McCann O.T.","McLaren S.J.","McLay K.","McMurray A.","Moore M.J.F.","Mullikin J.C.","Niblett D.","Nickerson T.","Novik K.L.","Oliver K.","Overton-Larty E.K.","Parker A.","Patel R.","Pearce A.V.","Peck A.I.","Phillimore B.J.C.T.","Phillips S.","Plumb R.W.","Porter K.M.","Ramsey Y.","Ranby S.A.","Rice C.M.","Ross M.T.","Searle S.M.","Sehra H.K.","Sheridan E.","Skuce C.D.","Smith S.","Smith M.","Spraggon L.","Squares S.L.","Steward C.A.","Sycamore N.","Tamlyn-Hall G.","Tester J.","Theaker A.J.","Thomas D.W.","Thorpe A.","Tracey A.","Tromans A.","Tubby B.","Wall M.","Wallis J.M.","West A.P.","White S.S.","Whitehead S.L.","Whittaker H.","Wild A.","Willey D.J.","Wilmer T.E.","Wood J.M.","Wray P.W.","Wyatt J.C.","Young L.","Younger R.M.","Bentley D.R.","Coulson A.","Durbin R.M.","Hubbard T.","Sulston J.E.","Dunham I.","Rogers J.","Beck S."],"citationCrossReferences":[{"database":"PubMed","id":"14574404"},{"database":"DOI","id":"10.1038/nature02055"}],"title":"The DNA sequence and analysis of human chromosome 6.","publicationDate":"2003","journal":"Nature","firstPage":"805","lastPage":"811","volume":"425"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AL133264","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL512428","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"CCDS","id":"CCDS64366.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_001269421.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001282492.2"}]},{"database":"AlphaFoldDB","id":"H3BNL8","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"H3BNL8","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"9606.ENSP00000454913","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"C6orf229","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"H3BNL8","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000454913","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"H3BNL8","properties":[{"key":"Description","value":"-"}]},{"database":"DNASU","id":"101928603","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000565469.4","properties":[{"key":"ProteinId","value":"ENSP00000454913.1"},{"key":"GeneId","value":"ENSG00000260286.4"}]},{"database":"GeneID","id":"101928603","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:101928603","properties":[{"key":"Description","value":"-"}]},{"database":"MANE-Select","id":"ENST00000565469.4","properties":[{"key":"ProteinId","value":"ENSP00000454913.1"},{"key":"RefSeqNucleotideId","value":"NM_001282492.2"},{"key":"RefSeqProteinId","value":"NP_001269421.1"}]},{"database":"UCSC","id":"uc032wor.2","properties":[{"key":"OrganismName","value":"human"}]},{"database":"AGR","id":"HGNC:49394","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"101928603","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"ARMH2","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:49394","properties":[{"key":"GeneName","value":"ARMH2"}]},{"database":"HPA","id":"ENSG00000260286","properties":[{"key":"ExpressionPatterns","value":"Tissue enriched (testis)"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000260286","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502S56C","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00530000068834","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_104877_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"H3BNL8","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"GWPENFA","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"5971936at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"H3BNL8","properties":[{"key":"Number of GO annotations","value":"0 GO annotations based on evolutionary models"}]},{"database":"PathwayCommons","id":"H3BNL8","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID-ORCS","id":"101928603","properties":[{"key":"hits","value":"3 hits in 877 CRISPR screens"}]},{"database":"Pharos","id":"H3BNL8","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:H3BNL8","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 6"}]},{"database":"RNAct","id":"H3BNL8","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000260286","properties":[{"key":"ExpressionPatterns","value":"Expressed in male germ line stem cell (sensu Vertebrata) in testis and 47 other cell types or tissues"}]},{"database":"InterPro","id":"IPR040268","properties":[{"key":"EntryName","value":"ARMH2"}]},{"database":"PANTHER","id":"PTHR37679","properties":[{"key":"EntryName","value":"ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR37679:SF1","properties":[{"key":"EntryName","value":"ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF17822","properties":[{"key":"EntryName","value":"ARMH2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MANSRFSCTQIWVKMYGYFAGLCRRLQKFWRVTVKGFFVKKKEKKIPSAETYFHEEKIVVLGQVLMNESLPIEKRAQAAQKIGLLAFTGGPPAGNFAAEYMEEVAHLLQDEELAPKIKILLLQSVACWCYLNPVSQKRAKSLQFIPILISFFEGRFESTIKSETNSYLLLKFWTCYVLSVMTCNNLSCVKELKDHSALKYHLQMLAAENWSGWTENFAEVLYFLIGFHRN","length":230,"molWeight":26547,"crc64":"28C24EE5AF74DAFD","md5":"0413C50B5C1D5B44EBC6723D28F95781"},"extraAttributes":{"countByFeatureType":{"Chain":1},"uniParcId":"UPI0002466C59"}}