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Transposons are derepressed due to DNA demethylation (PubMed:38359823)"}],"commentType":"DISRUPTION PHENOTYPE"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":185,"modifier":"EXACT"}},"description":"piRNA-mediated silencing protein C19orf84 homolog","featureId":"PRO_0000425556"},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":38,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":93,"modifier":"EXACT"},"end":{"value":185,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":25,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":26,"modifier":"EXACT"},"end":{"value":38,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":118,"modifier":"EXACT"},"end":{"value":130,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":139,"modifier":"EXACT"},"end":{"value":150,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-0221","category":"Biological process","name":"Differentiation"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0943","category":"Biological process","name":"RNA-mediated gene silencing"},{"id":"KW-0744","category":"Biological process","name":"Spermatogenesis"}],"references":[{"referenceNumber":1,"citation":{"id":"19468303","citationType":"journal article","authors":["Church D.M.","Goodstadt L.","Hillier L.W.","Zody M.C.","Goldstein S.","She X.","Bult C.J.","Agarwala R.","Cherry J.L.","DiCuccio M.","Hlavina W.","Kapustin Y.","Meric P.","Maglott D.","Birtle Z.","Marques A.C.","Graves T.","Zhou S.","Teague B.","Potamousis K.","Churas C.","Place M.","Herschleb J.","Runnheim R.","Forrest D.","Amos-Landgraf J.","Schwartz D.C.","Cheng Z.","Lindblad-Toh K.","Eichler E.E.","Ponting C.P."],"citationCrossReferences":[{"database":"PubMed","id":"19468303"},{"database":"DOI","id":"10.1371/journal.pbio.1000112"}],"title":"Lineage-specific biology revealed by a finished genome assembly of the mouse.","publicationDate":"2009","journal":"PLoS Biol.","firstPage":"E1000112","lastPage":"E1000112","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"38359823","citationType":"journal article","authors":["Zoch A.","Konieczny G.","Auchynnikava T.","Stallmeyer B.","Rotte N.","Heep M.","Berrens R.V.","Schito M.","Kabayama Y.","Schopp T.","Kliesch S.","Houston B.","Nagirnaja L.","O'Bryan M.K.","Aston K.I.","Conrad D.F.","Rappsilber J.","Allshire R.C.","Cook A.G.","Tuttelmann F.","O'Carroll D."],"citationCrossReferences":[{"database":"PubMed","id":"38359823"},{"database":"DOI","id":"10.1016/j.molcel.2024.01.014"}],"title":"C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line.","publicationDate":"2024","journal":"Mol. 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