{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"F4JZ68","secondaryAccessions":["Q94JU6","Q9FH58"],"uniProtkbId":"KN7H_ARATH","entryAudit":{"firstPublicDate":"2016-06-08","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2011-06-28","entryVersion":96,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Arabidopsis thaliana","commonName":"Mouse-ear cress","taxonId":3702,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Camelineae","Arabidopsis"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Kinesin-like protein KIN-7H"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"KIN7H"},"orderedLocusNames":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"Araport","id":"AT5G66310"}],"value":"At5g66310"}],"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"EMBL","id":"BAB10710.1"}],"value":"K1L20.9"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"16448571"}],"value":"Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous gene model prediction","sequence":"BAB10710.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1063,"modifier":"EXACT"}},"description":"Kinesin-like protein KIN-7H","featureId":"PRO_0000436466"},{"type":"Domain","location":{"start":{"value":18,"modifier":"EXACT"},"end":{"value":342,"modifier":"EXACT"}},"description":"Kinesin motor","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00283"}]},{"type":"Region","location":{"start":{"value":574,"modifier":"EXACT"},"end":{"value":664,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Coiled coil","location":{"start":{"value":351,"modifier":"EXACT"},"end":{"value":436,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Binding site","location":{"start":{"value":106,"modifier":"EXACT"},"end":{"value":113,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00283"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0493","category":"Cellular component","name":"Microtubule"},{"id":"KW-0505","category":"Molecular function","name":"Motor protein"},{"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"10718197","citationType":"journal article","authors":["Sato S.","Nakamura Y.","Kaneko T.","Katoh T.","Asamizu E.","Kotani H.","Tabata S."],"citationCrossReferences":[{"database":"PubMed","id":"10718197"},{"database":"DOI","id":"10.1093/dnares/7.1.31"}],"title":"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones.","publicationDate":"2000","journal":"DNA Res.","firstPage":"31","lastPage":"63","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"27862469","citationType":"journal article","authors":["Cheng C.Y.","Krishnakumar V.","Chan A.P.","Thibaud-Nissen F.","Schobel S.","Town C.D."],"citationCrossReferences":[{"database":"PubMed","id":"27862469"},{"database":"DOI","id":"10.1111/tpj.13415"}],"title":"Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.","publicationDate":"2017","journal":"Plant J.","firstPage":"789","lastPage":"804","volume":"89"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"CI-CI4AM1G71UC0S","citationType":"submission","authoringGroup":["The Arabidopsis Information Resource (TAIR)"],"title":"Community-consensus reference genome of Arabidopsis thaliana Col-0.","publicationDate":"FEB-2026","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"14593172","citationType":"journal article","authors":["Yamada K.","Lim J.","Dale J.M.","Chen H.","Shinn P.","Palm C.J.","Southwick A.M.","Wu H.C.","Kim C.J.","Nguyen M.","Pham P.K.","Cheuk R.F.","Karlin-Newmann G.","Liu S.X.","Lam B.","Sakano H.","Wu T.","Yu G.","Miranda M.","Quach H.L.","Tripp M.","Chang C.H.","Lee J.M.","Toriumi M.J.","Chan M.M.","Tang C.C.","Onodera C.S.","Deng J.M.","Akiyama K.","Ansari Y.","Arakawa T.","Banh J.","Banno F.","Bowser L.","Brooks S.Y.","Carninci P.","Chao Q.","Choy N.","Enju A.","Goldsmith A.D.","Gurjal M.","Hansen N.F.","Hayashizaki Y.","Johnson-Hopson C.","Hsuan V.W.","Iida K.","Karnes M.","Khan S.","Koesema E.","Ishida J.","Jiang P.X.","Jones T.","Kawai J.","Kamiya A.","Meyers C.","Nakajima M.","Narusaka M.","Seki M.","Sakurai T.","Satou M.","Tamse R.","Vaysberg M.","Wallender E.K.","Wong C.","Yamamura Y.","Yuan S.","Shinozaki K.","Davis R.W.","Theologis A.","Ecker J.R."],"citationCrossReferences":[{"database":"PubMed","id":"14593172"},{"database":"DOI","id":"10.1126/science.1088305"}],"title":"Empirical analysis of transcriptional activity in the Arabidopsis genome.","publicationDate":"2003","journal":"Science","firstPage":"842","lastPage":"846","volume":"302"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-425"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"11472632","citationType":"journal article","authors":["Reddy A.S.","Day I.S."],"citationCrossReferences":[{"database":"PubMed","id":"11472632"},{"database":"DOI","id":"10.1186/1471-2164-2-2"}],"title":"Kinesins in the Arabidopsis genome: a comparative analysis among eukaryotes.","publicationDate":"2001","journal":"BMC Genomics","firstPage":"2","lastPage":"2","volume":"2"},"referencePositions":["GENE FAMILY"]},{"referenceNumber":6,"citation":{"id":"16448571","citationType":"journal article","authors":["Richardson D.N.","Simmons M.P.","Reddy A.S."],"citationCrossReferences":[{"database":"PubMed","id":"16448571"},{"database":"DOI","id":"10.1186/1471-2164-7-18"}],"title":"Comprehensive comparative analysis of kinesins in photosynthetic eukaryotes.","publicationDate":"2006","journal":"BMC Genomics","firstPage":"18","lastPage":"18","volume":"7"},"referencePositions":["GENE FAMILY","NOMENCLATURE"]},{"referenceNumber":7,"citation":{"id":"22038119","citationType":"journal article","authors":["Zhu C.","Dixit R."],"citationCrossReferences":[{"database":"PubMed","id":"22038119"},{"database":"DOI","id":"10.1007/s00709-011-0343-9"}],"title":"Functions of the Arabidopsis kinesin superfamily of microtubule-based motor proteins.","publicationDate":"2012","journal":"Protoplasma","firstPage":"887","lastPage":"899","volume":"249"},"referencePositions":["REVIEW"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB022211","properties":[{"key":"ProteinId","value":"BAB10710.1"},{"key":"Status","value":"ALT_SEQ"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002688","properties":[{"key":"ProteinId","value":"AED98197.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002688","properties":[{"key":"ProteinId","value":"ANM68962.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002688","properties":[{"key":"ProteinId","value":"ANM68963.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408687","properties":[{"key":"ProteinId","value":"CAO7058002.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AF372930","properties":[{"key":"ProteinId","value":"AAK50070.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"RefSeq","id":"NP_001318888.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001345755.1"}]},{"database":"RefSeq","id":"NP_001330675.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001345756.1"}]},{"database":"RefSeq","id":"NP_201432.2","properties":[{"key":"NucleotideSequenceId","value":"NM_126029.3"}]},{"database":"AlphaFoldDB","id":"F4JZ68","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"F4JZ68","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"F4JZ68","properties":[{"key":"Number of interactors","value":"117"}]},{"database":"IntAct","id":"F4JZ68","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"3702.F4JZ68","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"F4JZ68","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"3702-F4JZ68","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"238207","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"836763","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT5G66310","properties":[{"key":"Description","value":"-"}]},{"database":"Araport","id":"AT5G66310","properties":[{"key":"Description","value":"-"}]},{"database":"TAIR","id":"AT5G66310","properties":[{"key":"GeneName","value":"-"}]},{"database":"eggNOG","id":"KOG0242","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_013407_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"F4JZ68","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"LEHQYPK","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"PRO","id":"PR:F4JZ68","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000006548","properties":[{"key":"Component","value":"Chromosome 5"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"ISM:TAIR"}]},{"database":"GO","id":"GO:0009506","properties":[{"key":"GoTerm","value":"C:plasmodesma"},{"key":"GoEvidenceType","value":"HDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"21533090"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0008017","properties":[{"key":"GoTerm","value":"F:microtubule binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0003777","properties":[{"key":"GoTerm","value":"F:microtubule motor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0007018","properties":[{"key":"GoTerm","value":"P:microtubule-based movement"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd01374","properties":[{"key":"EntryName","value":"KISc_CENP_E"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.40.850.10:FF:000016","properties":[{"key":"EntryName","value":"Kinesin-like protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.850.10","properties":[{"key":"EntryName","value":"Kinesin motor domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR027640","properties":[{"key":"EntryName","value":"Kinesin-like_fam"}]},{"database":"InterPro","id":"IPR019821","properties":[{"key":"EntryName","value":"Kinesin_motor_CS"}]},{"database":"InterPro","id":"IPR001752","properties":[{"key":"EntryName","value":"Kinesin_motor_dom"}]},{"database":"InterPro","id":"IPR036961","properties":[{"key":"EntryName","value":"Kinesin_motor_dom_sf"}]},{"database":"InterPro","id":"IPR021881","properties":[{"key":"EntryName","value":"NACK_C"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"PANTHER","id":"PTHR47968","properties":[{"key":"EntryName","value":"CENTROMERE PROTEIN E"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR47968:SF55","properties":[{"key":"EntryName","value":"KINESIN-LIKE PROTEIN KIN-7H"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF11995","properties":[{"key":"EntryName","value":"DUF3490"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00225","properties":[{"key":"EntryName","value":"Kinesin"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00380","properties":[{"key":"EntryName","value":"KINESINHEAVY"}]},{"database":"SMART","id":"SM00129","properties":[{"key":"EntryName","value":"KISc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52540","properties":[{"key":"EntryName","value":"P-loop containing nucleoside triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00411","properties":[{"key":"EntryName","value":"KINESIN_MOTOR_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50067","properties":[{"key":"EntryName","value":"KINESIN_MOTOR_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTTEDDDQMLGPSGTQEKIYVSVRMRPLNDKEKFRNDVPDWECINNTTIIYRSHLSISERSMYPSAYTFDRVFSPECCTRQVYEQGAKEVAFSVVSGVNASVFAYGQTSSGKTYTMSGITDCALVDIYGYIDKHKEREFILKFSAMEIYNESVRDLLSTDTSPLRLLDDPEKGTVVEKLTEETLRDWNHFKELLSVCKAQRQIGETALNEVSSRSHQILRLTVESIAREFSTNDKFSTLTATVNFIDLAGSERASQSLSAGTRLKEGCHINRSLLTLGTVIRKLSKEKTGHIPFRDSKLTRILQSSLGGNARTAIICTMSPARIHVEQSRNTLLFASCAKEVTTNAQVNVVMSDKALVKHLQRELAKLESELRSPSQASIVSDTTALLTEKDLEVEKLKKEVFQLAQQLEQARSEIKDLRRMVEEEKNQEKETLSTETEGLNVLMEHQYPKLRVRRTWDSENTTPLSPISAHRSSISPRSTEYSYEENVFQLSDFRIDSASSSPQQLAFVTPFLKVPLDDIHVTDTVDQSHVHKEEAIEEPHVQEERFYEMAEHTDGNSEDNCREVRCIETEKSDISIGPVENMPESSPDKYEAVTAEEPVSVTEPKNLQHPTEEAVCVTETKNLQHPTEAENEEEEEEERVKEVSGASPEPKQESNLTKNPALCDLECSPDEFDTSMSNLSRISTPPALITPSPEKPFSWIMERDSQLFRGMKLTRSRSCRPSLLSSPSSSWLEKDADTPPSWYDKEFIKTAERNLTMCDIKNQRLLQDEFSGRSMPTTWFERSLSDTQTVDAASHGVSNEMSPNESPFRPSDASVFELQTSGRASISQDRTEETAAQKDKQIIHRSMEEREQKFLASNSTKSFKDAAMDPIQDYLDTALNWPVEFKRLQREIIELWHVCKVSMAHRSYFFLLFRGDQKDCLYLEVELRRLKYIRESFAQNSNDGNNMTLISCTRALTRERYKLSKLMQRKLSKEERENLFLRWGIGLNTNHRRVQLARRLWSDYKDMGHVRESASLVGKLNGFVDMKLTSTEMFGVNYAFRPPRPKKSSLWKRSVLSLSFL","length":1063,"molWeight":121424,"crc64":"8F1443F6FBDFF736","md5":"065D8BF5C150348DE9473DE2F5B29198"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Domain":1,"Region":1,"Coiled coil":1,"Binding site":1},"uniParcId":"UPI0000197174"}}