{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"B0R4J4","uniProtkbId":"CHEF2_HALS3","entryAudit":{"firstPublicDate":"2014-05-14","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-04-08","entryVersion":71,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)","taxonId":478009,"lineage":["Archaea","Methanobacteriati","Methanobacteriota","Stenosarchaea group","Halobacteria","Halobacteriales","Halobacteriaceae","Halobacterium","Halobacterium salinarum NRC-34001"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Taxis protein CheF2"}}},"genes":[{"geneName":{"value":"cheF2"},"orderedLocusNames":[{"value":"OE_2404R"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"19291314"}],"value":"Involved in taxis signal transduction"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"19291314"}],"value":"Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"19291314"}],"value":"Deletion has only minimal effects"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the CheF taxis protein family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":287,"modifier":"EXACT"}},"description":"Taxis protein CheF2","featureId":"PRO_0000429072"}],"keywords":[{"id":"KW-0145","category":"Biological process","name":"Chemotaxis"}],"references":[{"referenceNumber":1,"citation":{"id":"18313895","citationType":"journal article","authors":["Pfeiffer F.","Schuster S.C.","Broicher A.","Falb M.","Palm P.","Rodewald K.","Ruepp A.","Soppa J.","Tittor J.","Oesterhelt D."],"citationCrossReferences":[{"database":"PubMed","id":"18313895"},{"database":"DOI","id":"10.1016/j.ygeno.2008.01.001"}],"title":"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1.","publicationDate":"2008","journal":"Genomics","firstPage":"335","lastPage":"346","volume":"91"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 29341 / DSM 671 / R1","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"19291314","citationType":"journal article","authors":["Schlesner M.","Miller A.","Streif S.","Staudinger W.F.","Muller J.","Scheffer B.","Siedler F.","Oesterhelt D."],"citationCrossReferences":[{"database":"PubMed","id":"19291314"},{"database":"DOI","id":"10.1186/1471-2180-9-56"}],"title":"Identification of Archaea-specific chemotaxis proteins which interact with the flagellar apparatus.","publicationDate":"2009","journal":"BMC Microbiol.","firstPage":"56","lastPage":"56","volume":"9"},"referencePositions":["FUNCTION","INTERACTION WITH CHE AND FLA PROTEINS","DISRUPTION PHENOTYPE","GENE NAME"],"referenceComments":[{"value":"ATCC 29341 / DSM 671 / R1","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AM774415","properties":[{"key":"ProteinId","value":"CAP13659.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_010902685.1","properties":[{"key":"NucleotideSequenceId","value":"NC_010364.1"}]},{"database":"AlphaFoldDB","id":"B0R4J4","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"B0R4J4","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"CAP13659","properties":[{"key":"ProteinId","value":"CAP13659"},{"key":"GeneId","value":"OE_2404R"}]},{"database":"GeneID","id":"68693771","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"89349358","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsl:OE_2404R","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_063179_0_0_2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"B0R4J4","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0006935","properties":[{"key":"GoTerm","value":"P:chemotaxis"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"1.10.10.10","properties":[{"key":"EntryName","value":"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR007381","properties":[{"key":"EntryName","value":"CheF1/F2"}]},{"database":"InterPro","id":"IPR036388","properties":[{"key":"EntryName","value":"WH-like_DNA-bd_sf"}]},{"database":"InterPro","id":"IPR036390","properties":[{"key":"EntryName","value":"WH_DNA-bd_sf"}]},{"database":"PANTHER","id":"PTHR42201","properties":[{"key":"EntryName","value":"TAXIS PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42201:SF1","properties":[{"key":"EntryName","value":"TAXIS PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF04283","properties":[{"key":"EntryName","value":"CheF-arch"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF026802","properties":[{"key":"EntryName","value":"UCP026802"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46785","properties":[{"key":"EntryName","value":"Winged helix' DNA-binding domain"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSESAIADFVSSFIPDTATHVEPVRGRVVMSKRRIVLAADDEKTTIPLNGVFDVQHETAPGDLARFFEDTVTIAYEHDEDRHVAVIEGGGSTVDRFVTLVFKALVHGTTVYAKHPARRGGRITDQPFEKGNLALSPGDLTITGDADTTIDLSTVSHFERVDREVNGSNKQLLSVRHMGSTGPITTELALSSGRKMNLLGRYIRLQYTHLKQELADVTLTSEEIEALVAIYSSGPNASLAAVLGVDASRVTMLLNDLIEKELVTDDDGIALTSLGRAAVSEHIEDVNL","length":287,"molWeight":31108,"crc64":"7296443D13EE4614","md5":"B094A0DFEAC89A36F6D8C0E002130F35"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"DISRUPTION PHENOTYPE":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI0000063795"}}