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Interacts with SRB9 and SRB10, components of the SRB8-11 complex (By similarity)"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Uniformly distributed on the cytoplasmic face of the mitochondrial outer membrane. This localization is dependent on FIS1. Reorganizes to punctate structures on mitochondria, corresponding to mitochondrial constriction sites, at a late step in mitochondrial division (By similarity)"}]},"subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Mitochondrion outer membrane","id":"SL-0172"},"topology":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Peripheral membrane protein","id":"SL-9903"},"orientation":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Cytoplasmic side","id":"SL-9910"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the WD repeat MDV1/CAF4 family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"EDN59941.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":645,"modifier":"EXACT"}},"description":"CCR4-associated factor 4","featureId":"PRO_0000330093"},{"type":"Repeat","location":{"start":{"value":319,"modifier":"EXACT"},"end":{"value":359,"modifier":"EXACT"}},"description":"WD 1"},{"type":"Repeat","location":{"start":{"value":362,"modifier":"EXACT"},"end":{"value":402,"modifier":"EXACT"}},"description":"WD 2"},{"type":"Repeat","location":{"start":{"value":424,"modifier":"EXACT"},"end":{"value":463,"modifier":"EXACT"}},"description":"WD 3"},{"type":"Repeat","location":{"start":{"value":481,"modifier":"EXACT"},"end":{"value":528,"modifier":"EXACT"}},"description":"WD 4"},{"type":"Repeat","location":{"start":{"value":529,"modifier":"EXACT"},"end":{"value":568,"modifier":"EXACT"}},"description":"WD 5"},{"type":"Repeat","location":{"start":{"value":570,"modifier":"EXACT"},"end":{"value":605,"modifier":"EXACT"}},"description":"WD 6"},{"type":"Repeat","location":{"start":{"value":616,"modifier":"EXACT"},"end":{"value":645,"modifier":"EXACT"}},"description":"WD 7"},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":274,"modifier":"EXACT"}},"description":"Required for interaction with FIS1 and MDV1","evidences":[{"evidenceCode":"ECO:0000250"}]},{"type":"Region","location":{"start":{"value":74,"modifier":"EXACT"},"end":{"value":126,"modifier":"EXACT"}},"description":"Sufficient for interaction with FIS1","evidences":[{"evidenceCode":"ECO:0000250"}]},{"type":"Region","location":{"start":{"value":242,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Coiled coil","location":{"start":{"value":160,"modifier":"EXACT"},"end":{"value":253,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Compositional bias","location":{"start":{"value":242,"modifier":"EXACT"},"end":{"value":254,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-0496","category":"Cellular component","name":"Mitochondrion"},{"id":"KW-1000","category":"Cellular component","name":"Mitochondrion outer membrane"},{"id":"KW-0677","category":"Domain","name":"Repeat"},{"id":"KW-0853","category":"Domain","name":"WD repeat"}],"references":[{"referenceNumber":1,"citation":{"id":"17652520","citationType":"journal article","authors":["Wei W.","McCusker J.H.","Hyman R.W.","Jones T.","Ning Y.","Cao Z.","Gu Z.","Bruno D.","Miranda M.","Nguyen M.","Wilhelmy J.","Komp C.","Tamse R.","Wang X.","Jia P.","Luedi P.","Oefner P.J.","David L.","Dietrich F.S.","Li Y.","Davis R.W.","Steinmetz L.M."],"citationCrossReferences":[{"database":"PubMed","id":"17652520"},{"database":"DOI","id":"10.1073/pnas.0701291104"}],"title":"Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789.","publicationDate":"2007","journal":"Proc. 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