{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"A2RUR9","secondaryAccessions":["O60311","Q6ZU57"],"uniProtkbId":"C144A_HUMAN","entryAudit":{"firstPublicDate":"2007-12-04","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2007-03-06","entryVersion":120,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Coiled-coil domain-containing protein 144A"}}},"genes":[{"geneName":{"value":"CCDC144A"},"synonyms":[{"value":"KIAA0565"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"32991878"}],"value":"May play a role in preventing the formation of kidney stones through inhibition of calcium oxalate monohydrate (COM) crystallization, attenuating COM-induced apoptotic injury to renal epithelial cells (PubMed:32991878). May exhibit antilithiatic (preventing the formation of kidney stones) activity through crystal binding, hindering the crystal attachment to renal epithelial cells, a pre-requisite to initiate inflammatory response (PubMed:32991878)"}],"commentType":"FUNCTION"},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"1"},"isoformIds":["A2RUR9-1"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"2"},"isoformIds":["A2RUR9-2"],"sequenceIds":["VSP_029787","VSP_029789","VSP_029791"],"isoformSequenceStatus":"Described"},{"name":{"value":"3"},"isoformIds":["A2RUR9-3"],"sequenceIds":["VSP_029788","VSP_029790","VSP_029791"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the CCDC144 family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"BAA25491.2","note":"Extended N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Frameshift","sequence":"BAA25491.2","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Frameshift","sequence":"BAC86369.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1427,"modifier":"EXACT"}},"description":"Coiled-coil domain-containing protein 144A","featureId":"PRO_0000312279"},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":32,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":87,"modifier":"EXACT"},"end":{"value":189,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":213,"modifier":"EXACT"},"end":{"value":261,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":453,"modifier":"EXACT"},"end":{"value":485,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":528,"modifier":"EXACT"},"end":{"value":586,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Coiled coil","location":{"start":{"value":490,"modifier":"EXACT"},"end":{"value":545,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Coiled coil","location":{"start":{"value":648,"modifier":"EXACT"},"end":{"value":1129,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Coiled coil","location":{"start":{"value":1155,"modifier":"EXACT"},"end":{"value":1309,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Compositional bias","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":11,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":129,"modifier":"EXACT"},"end":{"value":150,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":167,"modifier":"EXACT"},"end":{"value":178,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":224,"modifier":"EXACT"},"end":{"value":234,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":453,"modifier":"EXACT"},"end":{"value":467,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":528,"modifier":"EXACT"},"end":{"value":537,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":543,"modifier":"EXACT"},"end":{"value":552,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":563,"modifier":"EXACT"},"end":{"value":584,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Alternative sequence","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":697,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"9628581"}],"featureId":"VSP_029787","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":247,"modifier":"EXACT"},"end":{"value":526,"modifier":"EXACT"}},"description":"in isoform 3","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"14702039"}],"featureId":"VSP_029788","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":698,"modifier":"EXACT"},"end":{"value":701,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"9628581"}],"featureId":"VSP_029789","alternativeSequence":{"originalSequence":"LYDL","alternativeSequences":["MFNC"]}},{"type":"Alternative sequence","location":{"start":{"value":1124,"modifier":"EXACT"},"end":{"value":1124,"modifier":"EXACT"}},"description":"in isoform 3","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"14702039"}],"featureId":"VSP_029790","alternativeSequence":{"originalSequence":"K","alternativeSequences":["KVVMREFQQEWTDLLKQQPTSEATSRCHINLDETQDSKKKLGQIRSE"]}},{"type":"Alternative sequence","location":{"start":{"value":1367,"modifier":"EXACT"},"end":{"value":1427,"modifier":"EXACT"}},"description":"in isoform 2 and isoform 3","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"14702039"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"9628581"}],"featureId":"VSP_029791","alternativeSequence":{"originalSequence":"MQQKLQNDLTAEVAGSSQTGLHRIPQCSSFSSSSLHLLLCSICQPFFLILQLLLNMNLDPI","alternativeSequences":["VSYLFSFGVQISDRILVCYLVK"]}},{"type":"Sequence conflict","location":{"start":{"value":1085,"modifier":"EXACT"},"end":{"value":1085,"modifier":"EXACT"}},"description":"in Ref. 5; BAC86369","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"Q","alternativeSequences":["R"]}}],"keywords":[{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"9628581","citationType":"journal article","authors":["Nagase T.","Ishikawa K.","Miyajima N.","Tanaka A.","Kotani H.","Nomura N.","Ohara O."],"citationCrossReferences":[{"database":"PubMed","id":"9628581"},{"database":"DOI","id":"10.1093/dnares/5.1.31"}],"title":"Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.","publicationDate":"1998","journal":"DNA Res.","firstPage":"31","lastPage":"39","volume":"5"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)"],"referenceComments":[{"value":"Brain","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"CI-DJM6FN3D6P046","citationType":"submission","authors":["Ohara O.","Nagase T.","Ishikawa K."],"publicationDate":"DEC-1999","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["SEQUENCE REVISION"]},{"referenceNumber":3,"citation":{"id":"16625196","citationType":"journal article","authors":["Zody M.C.","Garber M.","Adams D.J.","Sharpe T.","Harrow J.","Lupski J.R.","Nicholson C.","Searle S.M.","Wilming L.","Young S.K.","Abouelleil A.","Allen N.R.","Bi W.","Bloom T.","Borowsky M.L.","Bugalter B.E.","Butler J.","Chang J.L.","Chen C.-K.","Cook A.","Corum B.","Cuomo C.A.","de Jong P.J.","DeCaprio D.","Dewar K.","FitzGerald M.","Gilbert J.","Gibson R.","Gnerre S.","Goldstein S.","Grafham D.V.","Grocock R.","Hafez N.","Hagopian D.S.","Hart E.","Norman C.H.","Humphray S.","Jaffe D.B.","Jones M.","Kamal M.","Khodiyar V.K.","LaButti K.","Laird G.","Lehoczky J.","Liu X.","Lokyitsang T.","Loveland J.","Lui A.","Macdonald P.","Major J.E.","Matthews L.","Mauceli E.","McCarroll S.A.","Mihalev A.H.","Mudge J.","Nguyen C.","Nicol R.","O'Leary S.B.","Osoegawa K.","Schwartz D.C.","Shaw-Smith C.","Stankiewicz P.","Steward C.","Swarbreck D.","Venkataraman V.","Whittaker C.A.","Yang X.","Zimmer A.R.","Bradley A.","Hubbard T.","Birren B.W.","Rogers J.","Lander E.S.","Nusbaum C."],"citationCrossReferences":[{"database":"PubMed","id":"16625196"},{"database":"DOI","id":"10.1038/nature04689"}],"title":"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.","publicationDate":"2006","journal":"Nature","firstPage":"1045","lastPage":"1049","volume":"440"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":4,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)"]},{"referenceNumber":5,"citation":{"id":"14702039","citationType":"journal article","authors":["Ota T.","Suzuki Y.","Nishikawa T.","Otsuki T.","Sugiyama T.","Irie R.","Wakamatsu A.","Hayashi K.","Sato H.","Nagai K.","Kimura K.","Makita H.","Sekine M.","Obayashi M.","Nishi T.","Shibahara T.","Tanaka T.","Ishii S.","Yamamoto J.","Saito K.","Kawai Y.","Isono Y.","Nakamura Y.","Nagahari K.","Murakami K.","Yasuda T.","Iwayanagi T.","Wagatsuma M.","Shiratori A.","Sudo H.","Hosoiri T.","Kaku Y.","Kodaira H.","Kondo H.","Sugawara M.","Takahashi M.","Kanda K.","Yokoi T.","Furuya T.","Kikkawa E.","Omura Y.","Abe K.","Kamihara K.","Katsuta N.","Sato K.","Tanikawa M.","Yamazaki M.","Ninomiya K.","Ishibashi T.","Yamashita H.","Murakawa K.","Fujimori K.","Tanai H.","Kimata M.","Watanabe M.","Hiraoka S.","Chiba Y.","Ishida S.","Ono Y.","Takiguchi S.","Watanabe S.","Yosida M.","Hotuta T.","Kusano J.","Kanehori K.","Takahashi-Fujii A.","Hara H.","Tanase T.-O.","Nomura Y.","Togiya S.","Komai F.","Hara R.","Takeuchi K.","Arita M.","Imose N.","Musashino K.","Yuuki H.","Oshima A.","Sasaki N.","Aotsuka S.","Yoshikawa Y.","Matsunawa H.","Ichihara T.","Shiohata N.","Sano S.","Moriya S.","Momiyama H.","Satoh N.","Takami S.","Terashima Y.","Suzuki O.","Nakagawa S.","Senoh A.","Mizoguchi H.","Goto Y.","Shimizu F.","Wakebe H.","Hishigaki H.","Watanabe T.","Sugiyama A.","Takemoto M.","Kawakami B.","Yamazaki M.","Watanabe K.","Kumagai A.","Itakura S.","Fukuzumi Y.","Fujimori Y.","Komiyama M.","Tashiro H.","Tanigami A.","Fujiwara T.","Ono T.","Yamada K.","Fujii Y.","Ozaki K.","Hirao M.","Ohmori Y.","Kawabata A.","Hikiji T.","Kobatake N.","Inagaki H.","Ikema Y.","Okamoto S.","Okitani R.","Kawakami T.","Noguchi S.","Itoh T.","Shigeta K.","Senba T.","Matsumura K.","Nakajima Y.","Mizuno T.","Morinaga M.","Sasaki M.","Togashi T.","Oyama M.","Hata H.","Watanabe M.","Komatsu T.","Mizushima-Sugano J.","Satoh T.","Shirai Y.","Takahashi Y.","Nakagawa K.","Okumura K.","Nagase T.","Nomura N.","Kikuchi H.","Masuho Y.","Yamashita R.","Nakai K.","Yada T.","Nakamura Y.","Ohara O.","Isogai T.","Sugano S."],"citationCrossReferences":[{"database":"PubMed","id":"14702039"},{"database":"DOI","id":"10.1038/ng1285"}],"title":"Complete sequencing and characterization of 21,243 full-length human cDNAs.","publicationDate":"2004","journal":"Nat. Genet.","firstPage":"40","lastPage":"45","volume":"36"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 238-1410 (ISOFORM 3)"],"referenceComments":[{"value":"Testis","type":"TISSUE"}]},{"referenceNumber":6,"citation":{"id":"32991878","citationType":"journal article","authors":["Narula S.","Tandon S.","Kumar D.","Varshney S.","Adlakha K.","Sengupta S.","Singh S.K.","Tandon C."],"citationCrossReferences":[{"database":"PubMed","id":"32991878"},{"database":"DOI","id":"10.1016/j.lfs.2020.118498"}],"title":"Human kidney stone matrix proteins alleviate hyperoxaluria induced renal stress by targeting cell-crystal interactions.","publicationDate":"2020","journal":"Life Sci.","firstPage":"118498","lastPage":"118498","volume":"262"},"referencePositions":["FUNCTION"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB011137","properties":[{"key":"ProteinId","value":"BAA25491.2"},{"key":"Status","value":"ALT_SEQ"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AC098850","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC133019","properties":[{"key":"ProteinId","value":"AAI33020.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK125971","properties":[{"key":"ProteinId","value":"BAC86369.1"},{"key":"Status","value":"ALT_FRAME"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS45621.1","properties":[{"key":"Description","value":"-"}],"isoformId":"A2RUR9-1"},{"database":"RefSeq","id":"NP_055510.1","properties":[{"key":"NucleotideSequenceId","value":"NM_014695.3"}],"isoformId":"A2RUR9-1"},{"database":"AlphaFoldDB","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"115069","properties":[{"key":"Interactions","value":"8"}]},{"database":"FunCoup","id":"A2RUR9","properties":[{"key":"Number of interactors","value":"16"}]},{"database":"IntAct","id":"A2RUR9","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"9606.ENSP00000353717","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"SwissPalm","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"CCDC144A","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000353717","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"516","properties":[{"key":"Description","value":"-"}],"isoformId":"A2RUR9-1"},{"database":"ProteomicsDB","id":"517","properties":[{"key":"Description","value":"-"}],"isoformId":"A2RUR9-2"},{"database":"ProteomicsDB","id":"518","properties":[{"key":"Description","value":"-"}],"isoformId":"A2RUR9-3"},{"database":"Pumba","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"6447","properties":[{"key":"antibodies","value":"38 antibodies from 11 providers"}]},{"database":"DNASU","id":"9720","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000360524.12","properties":[{"key":"ProteinId","value":"ENSP00000353717.8"},{"key":"GeneId","value":"ENSG00000170160.20"}],"isoformId":"A2RUR9-1"},{"database":"GeneID","id":"9720","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:9720","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc002gqk.2","properties":[{"key":"OrganismName","value":"human"}],"isoformId":"A2RUR9-1"},{"database":"AGR","id":"HGNC:29072","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA162381473","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"9720","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"9720","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"CCDC144A","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:29072","properties":[{"key":"GeneName","value":"CCDC144A"}]},{"database":"HPA","id":"ENSG00000170160","properties":[{"key":"ExpressionPatterns","value":"Tissue enhanced (retina)"}]},{"database":"MIM","id":"619413","properties":[{"key":"Type","value":"gene"}]},{"database":"OpenTargets","id":"ENSG00000170160","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000170160","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG0504","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00940000166080","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"9483696at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"A2RUR9","properties":[{"key":"Number of GO annotations","value":"0 GO annotations based on evolutionary models"}]},{"database":"PhylomeDB","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000170160","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"9720","properties":[{"key":"hits","value":"151 hits in 1095 CRISPR screens"}]},{"database":"ChiTaRS","id":"CCDC144A","properties":[{"key":"OrganismName","value":"human"}]},{"database":"GenomeRNAi","id":"9720","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"A2RUR9","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:A2RUR9","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 17"}]},{"database":"RNAct","id":"A2RUR9","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000170160","properties":[{"key":"ExpressionPatterns","value":"Expressed in male germ line stem cell (sensu Vertebrata) in testis and 104 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"A2RUR9","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"InterPro","id":"IPR040118","properties":[{"key":"EntryName","value":"C144A/B/C"}]},{"database":"InterPro","id":"IPR039497","properties":[{"key":"EntryName","value":"CC144C-like_CC_dom"}]},{"database":"InterPro","id":"IPR021885","properties":[{"key":"EntryName","value":"DUF3496"}]},{"database":"PANTHER","id":"PTHR22245","properties":[{"key":"EntryName","value":"COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22245:SF3","properties":[{"key":"EntryName","value":"COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF14915","properties":[{"key":"EntryName","value":"CCDC144C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12001","properties":[{"key":"EntryName","value":"DUF3496"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MASWGGEKRGGAEGSPKPAVYATRKTPSVGSQGDQWYLGYPGDQWSSGFPYSWWKNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHILAPGDTGVDKRDRKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPSMPENQSATKELGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDSELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKFHLHENKLDCDNDNKPGIGHIFSTDKNFHNDASTKKARNPEVVMVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQTRSRSLFTAYATRPVLESPCVGNLNDSEGLNRKHIPRKKRSALKDMESYLLKMQQKLQNDLTAEVAGSSQTGLHRIPQCSSFSSSSLHLLLCSICQPFFLILQLLLNMNLDPI","length":1427,"molWeight":165125,"crc64":"9538A4F523D8D5C5","md5":"D545F2D7CEBC57395D097F0086D92587"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"ALTERNATIVE PRODUCTS":3,"SIMILARITY":1,"SEQUENCE CAUTION":3},"countByFeatureType":{"Chain":1,"Region":5,"Coiled coil":3,"Compositional bias":8,"Alternative sequence":5,"Sequence conflict":1},"uniParcId":"UPI0000F095D0"}}