{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"A2AWL7","secondaryAccessions":["A2AWL6","Q3TS36","Q6A056","Q8BQX1","Q8CCL4","Q9QXJ5"],"uniProtkbId":"MGAP_MOUSE","entryAudit":{"firstPublicDate":"2008-07-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2007-02-20","entryVersion":139,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Mus musculus","commonName":"Mouse","taxonId":10090,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Glires","Rodentia","Myomorpha","Muroidea","Muridae","Murinae","Mus","Mus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"value":"MAX gene-associated protein"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"10601024"}],"value":"Mga"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15368895"}],"value":"Kiaa4252"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10601024"}],"value":"Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BACC1, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with ZMYND11 (By similarity). Interacts with MAX. Requires heterodimerization with MAX for E-box binding"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Nucleus","id":"SL-0191"}}]},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"1"},"isoformIds":["A2AWL7-1"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"2"},"isoformIds":["A2AWL7-2"],"sequenceIds":["VSP_034539","VSP_034540","VSP_034541","VSP_034542"],"isoformSequenceStatus":"Described"},{"name":{"value":"3"},"isoformIds":["A2AWL7-3"],"sequenceIds":["VSP_034538"],"isoformSequenceStatus":"Described"},{"name":{"value":"4"},"isoformIds":["A2AWL7-4"],"sequenceIds":["VSP_034536","VSP_034537"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"39545409"}],"value":"Highly expressed in germ cells and granulosa cells"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10601024"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"39545409"}],"value":"Expressed at 9.5 dpc, 10 dpc and 10.5 dpc in the limb buds, branchial arches and the tail region (PubMed:10601024). In germ cells and granulosa cells, expressed from early embryonic through adult developmental stages (PubMed:39545409)"}],"commentType":"DEVELOPMENTAL STAGE"},{"texts":[{"value":"Transcription repression is enhanced or dependent on the presence of the T-box DNA-binding domain"}],"commentType":"DOMAIN"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"BAD32240.1","note":"Extended N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":3003,"modifier":"EXACT"}},"description":"MAX gene-associated protein","featureId":"PRO_0000342693"},{"type":"Domain","location":{"start":{"value":2362,"modifier":"EXACT"},"end":{"value":2413,"modifier":"EXACT"}},"description":"bHLH","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00981"}]},{"type":"DNA binding","location":{"start":{"value":84,"modifier":"EXACT"},"end":{"value":260,"modifier":"EXACT"}},"description":"T-box","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00201"}]},{"type":"Region","location":{"start":{"value":259,"modifier":"EXACT"},"end":{"value":290,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":553,"modifier":"EXACT"},"end":{"value":647,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":871,"modifier":"EXACT"},"end":{"value":946,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":967,"modifier":"EXACT"},"end":{"value":987,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1111,"modifier":"EXACT"},"end":{"value":1130,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1186,"modifier":"EXACT"},"end":{"value":1215,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1246,"modifier":"EXACT"},"end":{"value":1277,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1297,"modifier":"EXACT"},"end":{"value":1323,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1376,"modifier":"EXACT"},"end":{"value":1424,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1476,"modifier":"EXACT"},"end":{"value":1508,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1722,"modifier":"EXACT"},"end":{"value":1746,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1856,"modifier":"EXACT"},"end":{"value":1885,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1920,"modifier":"EXACT"},"end":{"value":1954,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1964,"modifier":"EXACT"},"end":{"value":1983,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1988,"modifier":"EXACT"},"end":{"value":2038,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":2087,"modifier":"EXACT"},"end":{"value":2110,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":2207,"modifier":"EXACT"},"end":{"value":2255,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":2515,"modifier":"EXACT"},"end":{"value":2534,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":2629,"modifier":"EXACT"},"end":{"value":2654,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":2877,"modifier":"EXACT"},"end":{"value":2917,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":259,"modifier":"EXACT"},"end":{"value":277,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":278,"modifier":"EXACT"},"end":{"value":288,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":595,"modifier":"EXACT"},"end":{"value":607,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":610,"modifier":"EXACT"},"end":{"value":621,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":871,"modifier":"EXACT"},"end":{"value":913,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":937,"modifier":"EXACT"},"end":{"value":946,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":969,"modifier":"EXACT"},"end":{"value":978,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1113,"modifier":"EXACT"},"end":{"value":1122,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1248,"modifier":"EXACT"},"end":{"value":1269,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1303,"modifier":"EXACT"},"end":{"value":1315,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1488,"modifier":"EXACT"},"end":{"value":1507,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1735,"modifier":"EXACT"},"end":{"value":1746,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1859,"modifier":"EXACT"},"end":{"value":1880,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1964,"modifier":"EXACT"},"end":{"value":1976,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":2088,"modifier":"EXACT"},"end":{"value":2101,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":2220,"modifier":"EXACT"},"end":{"value":2232,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":2242,"modifier":"EXACT"},"end":{"value":2255,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":2520,"modifier":"EXACT"},"end":{"value":2534,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":2629,"modifier":"EXACT"},"end":{"value":2651,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Modified residue","location":{"start":{"value":531,"modifier":"EXACT"},"end":{"value":531,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":604,"modifier":"EXACT"},"end":{"value":604,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":848,"modifier":"EXACT"},"end":{"value":848,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":921,"modifier":"EXACT"},"end":{"value":921,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":1423,"modifier":"EXACT"},"end":{"value":1423,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":1450,"modifier":"EXACT"},"end":{"value":1450,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":2206,"modifier":"EXACT"},"end":{"value":2206,"modifier":"EXACT"}},"description":"Omega-N-methylarginine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":2480,"modifier":"EXACT"},"end":{"value":2480,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":2849,"modifier":"EXACT"},"end":{"value":2849,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Modified residue","location":{"start":{"value":2860,"modifier":"EXACT"},"end":{"value":2860,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":4,"modifier":"EXACT"},"end":{"value":4,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":178,"modifier":"EXACT"},"end":{"value":178,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":323,"modifier":"EXACT"},"end":{"value":323,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":329,"modifier":"EXACT"},"end":{"value":329,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":348,"modifier":"EXACT"},"end":{"value":348,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":431,"modifier":"EXACT"},"end":{"value":431,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":458,"modifier":"EXACT"},"end":{"value":458,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":463,"modifier":"EXACT"},"end":{"value":463,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":480,"modifier":"EXACT"},"end":{"value":480,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":567,"modifier":"EXACT"},"end":{"value":567,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":610,"modifier":"EXACT"},"end":{"value":610,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":651,"modifier":"EXACT"},"end":{"value":651,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":782,"modifier":"EXACT"},"end":{"value":782,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":788,"modifier":"EXACT"},"end":{"value":788,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":814,"modifier":"EXACT"},"end":{"value":814,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":823,"modifier":"EXACT"},"end":{"value":823,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":925,"modifier":"EXACT"},"end":{"value":925,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":987,"modifier":"EXACT"},"end":{"value":987,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1088,"modifier":"EXACT"},"end":{"value":1088,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1136,"modifier":"EXACT"},"end":{"value":1136,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1158,"modifier":"EXACT"},"end":{"value":1158,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1194,"modifier":"EXACT"},"end":{"value":1194,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1202,"modifier":"EXACT"},"end":{"value":1202,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1454,"modifier":"EXACT"},"end":{"value":1454,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1495,"modifier":"EXACT"},"end":{"value":1495,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1937,"modifier":"EXACT"},"end":{"value":1937,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":1944,"modifier":"EXACT"},"end":{"value":1944,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2060,"modifier":"EXACT"},"end":{"value":2060,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2084,"modifier":"EXACT"},"end":{"value":2084,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2104,"modifier":"EXACT"},"end":{"value":2104,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2152,"modifier":"EXACT"},"end":{"value":2152,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2179,"modifier":"EXACT"},"end":{"value":2179,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2225,"modifier":"EXACT"},"end":{"value":2225,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2317,"modifier":"EXACT"},"end":{"value":2317,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2352,"modifier":"EXACT"},"end":{"value":2352,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2396,"modifier":"EXACT"},"end":{"value":2396,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2471,"modifier":"EXACT"},"end":{"value":2471,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2568,"modifier":"EXACT"},"end":{"value":2568,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2618,"modifier":"EXACT"},"end":{"value":2618,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2724,"modifier":"EXACT"},"end":{"value":2724,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Cross-link","location":{"start":{"value":2979,"modifier":"EXACT"},"end":{"value":2979,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8IWI9"}]},{"type":"Alternative sequence","location":{"start":{"value":669,"modifier":"EXACT"},"end":{"value":671,"modifier":"EXACT"}},"description":"in isoform 4","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"16141072"}],"featureId":"VSP_034536","alternativeSequence":{"originalSequence":"EAL","alternativeSequences":["VWL"]}},{"type":"Alternative sequence","location":{"start":{"value":672,"modifier":"EXACT"},"end":{"value":3003,"modifier":"EXACT"}},"description":"in isoform 4","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"16141072"}],"featureId":"VSP_034537","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":727,"modifier":"EXACT"},"end":{"value":805,"modifier":"EXACT"}},"description":"in isoform 3","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"16141072"}],"featureId":"VSP_034538","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":1214,"modifier":"EXACT"},"end":{"value":1214,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15368895"}],"featureId":"VSP_034539","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":1521,"modifier":"EXACT"},"end":{"value":1728,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15368895"}],"featureId":"VSP_034540","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":1754,"modifier":"EXACT"},"end":{"value":1754,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15368895"}],"featureId":"VSP_034541","alternativeSequence":{"originalSequence":"L","alternativeSequences":["LLIPVQQGSPTLRPIQNPQLQGQRMVLQPVRGPSGMNLFR"]}},{"type":"Alternative sequence","location":{"start":{"value":2466,"modifier":"EXACT"},"end":{"value":3003,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15368895"}],"featureId":"VSP_034542","alternativeSequence":{}},{"type":"Sequence conflict","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":11,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"N","alternativeSequences":["T"]}},{"type":"Sequence conflict","location":{"start":{"value":195,"modifier":"EXACT"},"end":{"value":195,"modifier":"EXACT"}},"description":"in Ref. 3; BAC27930","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"H","alternativeSequences":["Y"]}},{"type":"Sequence conflict","location":{"start":{"value":217,"modifier":"EXACT"},"end":{"value":217,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"Q","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":342,"modifier":"EXACT"},"end":{"value":342,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"H","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":346,"modifier":"EXACT"},"end":{"value":346,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"Q","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":349,"modifier":"EXACT"},"end":{"value":349,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"H","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":359,"modifier":"EXACT"},"end":{"value":359,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"S","alternativeSequences":["R"]}},{"type":"Sequence conflict","location":{"start":{"value":403,"modifier":"EXACT"},"end":{"value":403,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"Q","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":458,"modifier":"EXACT"},"end":{"value":458,"modifier":"EXACT"}},"description":"in Ref. 3; BAC32658","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"K","alternativeSequences":["R"]}},{"type":"Sequence conflict","location":{"start":{"value":634,"modifier":"EXACT"},"end":{"value":634,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"T","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":666,"modifier":"EXACT"},"end":{"value":666,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"E","alternativeSequences":["D"]}},{"type":"Sequence conflict","location":{"start":{"value":752,"modifier":"EXACT"},"end":{"value":752,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"A","alternativeSequences":["G"]}},{"type":"Sequence conflict","location":{"start":{"value":757,"modifier":"EXACT"},"end":{"value":757,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"F","alternativeSequences":["L"]}},{"type":"Sequence conflict","location":{"start":{"value":844,"modifier":"EXACT"},"end":{"value":844,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"N","alternativeSequences":["D"]}},{"type":"Sequence conflict","location":{"start":{"value":873,"modifier":"EXACT"},"end":{"value":873,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"S","alternativeSequences":["C"]}},{"type":"Sequence conflict","location":{"start":{"value":903,"modifier":"EXACT"},"end":{"value":903,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"T","alternativeSequences":["A"]}},{"type":"Sequence conflict","location":{"start":{"value":1061,"modifier":"EXACT"},"end":{"value":1061,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"E","alternativeSequences":["D"]}},{"type":"Sequence conflict","location":{"start":{"value":1136,"modifier":"EXACT"},"end":{"value":1136,"modifier":"EXACT"}},"description":"in Ref. 5; BAD32240","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"K","alternativeSequences":["E"]}},{"type":"Sequence conflict","location":{"start":{"value":1191,"modifier":"EXACT"},"end":{"value":1191,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"S","alternativeSequences":["ST"]}},{"type":"Sequence conflict","location":{"start":{"value":1593,"modifier":"EXACT"},"end":{"value":1593,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"P","alternativeSequences":["L"]}},{"type":"Sequence conflict","location":{"start":{"value":1753,"modifier":"EXACT"},"end":{"value":1755,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"LLH","alternativeSequences":["FDVG"]}},{"type":"Sequence conflict","location":{"start":{"value":1763,"modifier":"EXACT"},"end":{"value":1763,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["F"]}},{"type":"Sequence conflict","location":{"start":{"value":1826,"modifier":"EXACT"},"end":{"value":1826,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"S","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":1845,"modifier":"EXACT"},"end":{"value":1845,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"F","alternativeSequences":["L"]}},{"type":"Sequence conflict","location":{"start":{"value":2033,"modifier":"EXACT"},"end":{"value":2033,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"V","alternativeSequences":["A"]}},{"type":"Sequence conflict","location":{"start":{"value":2043,"modifier":"EXACT"},"end":{"value":2043,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"M","alternativeSequences":["I"]}},{"type":"Sequence conflict","location":{"start":{"value":2478,"modifier":"EXACT"},"end":{"value":2478,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"C","alternativeSequences":["G"]}},{"type":"Sequence conflict","location":{"start":{"value":2800,"modifier":"EXACT"},"end":{"value":2802,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"RAF","alternativeSequences":["ARLI"]}},{"type":"Sequence conflict","location":{"start":{"value":2809,"modifier":"EXACT"},"end":{"value":2809,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"G","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":2814,"modifier":"EXACT"},"end":{"value":2814,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"F","alternativeSequences":["Y"]}},{"type":"Sequence conflict","location":{"start":{"value":2819,"modifier":"EXACT"},"end":{"value":2821,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"LGA","alternativeSequences":["MGT"]}},{"type":"Sequence conflict","location":{"start":{"value":2830,"modifier":"EXACT"},"end":{"value":2830,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"Q","alternativeSequences":["L"]}},{"type":"Sequence conflict","location":{"start":{"value":2835,"modifier":"EXACT"},"end":{"value":2835,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"S","alternativeSequences":["T"]}},{"type":"Sequence conflict","location":{"start":{"value":2852,"modifier":"EXACT"},"end":{"value":2853,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"EK","alternativeSequences":["VR"]}},{"type":"Sequence conflict","location":{"start":{"value":2865,"modifier":"EXACT"},"end":{"value":2865,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["H"]}},{"type":"Sequence conflict","location":{"start":{"value":2877,"modifier":"EXACT"},"end":{"value":2877,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["R"]}},{"type":"Sequence conflict","location":{"start":{"value":2928,"modifier":"EXACT"},"end":{"value":2928,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"A","alternativeSequences":["T"]}},{"type":"Sequence conflict","location":{"start":{"value":2969,"modifier":"EXACT"},"end":{"value":2969,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"A","alternativeSequences":["T"]}},{"type":"Sequence conflict","location":{"start":{"value":2971,"modifier":"EXACT"},"end":{"value":2971,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"I","alternativeSequences":["S"]}},{"type":"Sequence conflict","location":{"start":{"value":2998,"modifier":"EXACT"},"end":{"value":2998,"modifier":"EXACT"}},"description":"in Ref. 1; AAF24761","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"S","alternativeSequences":["L"]}}],"keywords":[{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"id":"KW-1017","category":"PTM","name":"Isopeptide bond"},{"id":"KW-0488","category":"PTM","name":"Methylation"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0678","category":"Molecular function","name":"Repressor"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"},{"id":"KW-0832","category":"PTM","name":"Ubl conjugation"}],"references":[{"referenceNumber":1,"citation":{"id":"10601024","citationType":"journal article","authors":["Hurlin P.J.","Steingrimsson E.","Copeland N.G.","Jenkins N.A.","Eisenman R.N."],"citationCrossReferences":[{"database":"PubMed","id":"10601024"},{"database":"DOI","id":"10.1093/emboj/18.24.7019"}],"title":"Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif.","publicationDate":"1999","journal":"EMBO J.","firstPage":"7019","lastPage":"7028","volume":"18"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)","FUNCTION","DEVELOPMENTAL STAGE"]},{"referenceNumber":2,"citation":{"id":"CI-30BHFFVAJBKLO","citationType":"journal article","authors":["Hurlin P.J.","Steingrimsson E.","Copeland N.G.","Jenkins N.A.","Eisenman R.N."],"publicationDate":"2000","journal":"EMBO J.","firstPage":"3841","lastPage":"3841","volume":"19"},"referencePositions":["ERRATUM OF PUBMED:10601024"]},{"referenceNumber":3,"citation":{"id":"16141072","citationType":"journal article","authors":["Carninci P.","Kasukawa T.","Katayama S.","Gough J.","Frith M.C.","Maeda N.","Oyama R.","Ravasi T.","Lenhard B.","Wells C.","Kodzius R.","Shimokawa K.","Bajic V.B.","Brenner S.E.","Batalov S.","Forrest A.R.","Zavolan M.","Davis M.J.","Wilming L.G.","Aidinis V.","Allen J.E.","Ambesi-Impiombato A.","Apweiler R.","Aturaliya R.N.","Bailey T.L.","Bansal M.","Baxter L.","Beisel K.W.","Bersano T.","Bono H.","Chalk A.M.","Chiu K.P.","Choudhary V.","Christoffels A.","Clutterbuck D.R.","Crowe M.L.","Dalla E.","Dalrymple B.P.","de Bono B.","Della Gatta G.","di Bernardo D.","Down T.","Engstrom P.","Fagiolini M.","Faulkner G.","Fletcher C.F.","Fukushima T.","Furuno M.","Futaki S.","Gariboldi M.","Georgii-Hemming P.","Gingeras T.R.","Gojobori T.","Green R.E.","Gustincich S.","Harbers M.","Hayashi Y.","Hensch T.K.","Hirokawa N.","Hill D.","Huminiecki L.","Iacono M.","Ikeo K.","Iwama A.","Ishikawa T.","Jakt M.","Kanapin A.","Katoh M.","Kawasawa Y.","Kelso J.","Kitamura H.","Kitano H.","Kollias G.","Krishnan S.P.","Kruger A.","Kummerfeld S.K.","Kurochkin I.V.","Lareau L.F.","Lazarevic D.","Lipovich L.","Liu J.","Liuni S.","McWilliam S.","Madan Babu M.","Madera M.","Marchionni L.","Matsuda H.","Matsuzawa S.","Miki H.","Mignone F.","Miyake S.","Morris K.","Mottagui-Tabar S.","Mulder N.","Nakano N.","Nakauchi H.","Ng P.","Nilsson R.","Nishiguchi S.","Nishikawa S.","Nori F.","Ohara O.","Okazaki Y.","Orlando V.","Pang K.C.","Pavan W.J.","Pavesi G.","Pesole G.","Petrovsky N.","Piazza S.","Reed J.","Reid J.F.","Ring B.Z.","Ringwald M.","Rost B.","Ruan Y.","Salzberg S.L.","Sandelin A.","Schneider C.","Schoenbach C.","Sekiguchi K.","Semple C.A.","Seno S.","Sessa L.","Sheng Y.","Shibata Y.","Shimada H.","Shimada K.","Silva D.","Sinclair B.","Sperling S.","Stupka E.","Sugiura K.","Sultana R.","Takenaka Y.","Taki K.","Tammoja K.","Tan S.L.","Tang S.","Taylor M.S.","Tegner J.","Teichmann S.A.","Ueda H.R.","van Nimwegen E.","Verardo R.","Wei C.L.","Yagi K.","Yamanishi H.","Zabarovsky E.","Zhu S.","Zimmer A.","Hide W.","Bult C.","Grimmond S.M.","Teasdale R.D.","Liu E.T.","Brusic V.","Quackenbush J.","Wahlestedt C.","Mattick J.S.","Hume D.A.","Kai C.","Sasaki D.","Tomaru Y.","Fukuda S.","Kanamori-Katayama M.","Suzuki M.","Aoki J.","Arakawa T.","Iida J.","Imamura K.","Itoh M.","Kato T.","Kawaji H.","Kawagashira N.","Kawashima T.","Kojima M.","Kondo S.","Konno H.","Nakano K.","Ninomiya N.","Nishio T.","Okada M.","Plessy C.","Shibata K.","Shiraki T.","Suzuki S.","Tagami M.","Waki K.","Watahiki A.","Okamura-Oho Y.","Suzuki H.","Kawai J.","Hayashizaki Y."],"citationCrossReferences":[{"database":"PubMed","id":"16141072"},{"database":"DOI","id":"10.1126/science.1112014"}],"title":"The transcriptional landscape of the mammalian genome.","publicationDate":"2005","journal":"Science","firstPage":"1559","lastPage":"1563","volume":"309"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)","NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1129 (ISOFORM 1)","NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1129 (ISOFORM 3)"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"},{"value":"Colon","type":"TISSUE"},{"value":"Corpora quadrigemina","type":"TISSUE"},{"value":"Embryo","type":"TISSUE"},{"value":"Olfactory bulb","type":"TISSUE"}]},{"referenceNumber":4,"citation":{"id":"19468303","citationType":"journal article","authors":["Church D.M.","Goodstadt L.","Hillier L.W.","Zody M.C.","Goldstein S.","She X.","Bult C.J.","Agarwala R.","Cherry J.L.","DiCuccio M.","Hlavina W.","Kapustin Y.","Meric P.","Maglott D.","Birtle Z.","Marques A.C.","Graves T.","Zhou S.","Teague B.","Potamousis K.","Churas C.","Place M.","Herschleb J.","Runnheim R.","Forrest D.","Amos-Landgraf J.","Schwartz D.C.","Cheng Z.","Lindblad-Toh K.","Eichler E.E.","Ponting C.P."],"citationCrossReferences":[{"database":"PubMed","id":"19468303"},{"database":"DOI","id":"10.1371/journal.pbio.1000112"}],"title":"Lineage-specific biology revealed by a finished genome assembly of the mouse.","publicationDate":"2009","journal":"PLoS Biol.","firstPage":"E1000112","lastPage":"E1000112","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"15368895","citationType":"journal article","authors":["Okazaki N.","Kikuno R.","Ohara R.","Inamoto S.","Koseki H.","Hiraoka S.","Saga Y.","Seino S.","Nishimura M.","Kaisho T.","Hoshino K.","Kitamura H.","Nagase T.","Ohara O.","Koga H."],"citationCrossReferences":[{"database":"PubMed","id":"15368895"},{"database":"DOI","id":"10.1093/dnares/11.3.205"}],"title":"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.","publicationDate":"2004","journal":"DNA Res.","firstPage":"205","lastPage":"218","volume":"11"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-2465 (ISOFORM 2)"],"referenceComments":[{"value":"Thymus","type":"TISSUE"}]},{"referenceNumber":6,"citation":{"id":"39545409","citationType":"journal article","authors":["Tang S.","Guo T.","Song C.","Wang L.","Zhang J.","Rajkovic A.","Lin X.","Chen S.","Liu Y.","Tian W.","Wu B.","Wang S.","Wang W.","Lai Y.","Wang A.","Xu S.","Jin L.","Ke H.","Zhao S.","Li Y.","Qin Y.","Zhang F.","Chen Z.J."],"citationCrossReferences":[{"database":"PubMed","id":"39545409"},{"database":"DOI","id":"10.1172/jci183758"}],"title":"MGA loss-of-function variants cause premature ovarian insufficiency.","publicationDate":"2024","journal":"J. Clin. Invest.","firstPage":"0","lastPage":"0","volume":"134"},"referencePositions":["TISSUE SPECIFICITY","DEVELOPMENTAL STAGE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF205935","properties":[{"key":"ProteinId","value":"AAF24761.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK032570","properties":[{"key":"ProteinId","value":"BAC27930.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK046252","properties":[{"key":"ProteinId","value":"BAC32658.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK133775","properties":[{"key":"ProteinId","value":"BAE21832.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK162302","properties":[{"key":"ProteinId","value":"BAE36840.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AL954662","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AK172962","properties":[{"key":"ProteinId","value":"BAD32240.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"RefSeq","id":"NP_038748.2","properties":[{"key":"NucleotideSequenceId","value":"NM_013720.2"}]},{"database":"AlphaFoldDB","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"205889","properties":[{"key":"Interactions","value":"27"}]},{"database":"FunCoup","id":"A2AWL7","properties":[{"key":"Number of interactors","value":"1902"}]},{"database":"IntAct","id":"A2AWL7","properties":[{"key":"Interactions","value":"6"}]},{"database":"STRING","id":"10090.ENSMUSP00000106401","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"A2AWL7","properties":[{"key":"glycosylation","value":"9 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (7 sites)"}]},{"database":"iPTMnet","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"10090-ENSMUSP00000106401","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"295896","properties":[{"key":"Description","value":"-"}],"isoformId":"A2AWL7-1"},{"database":"ProteomicsDB","id":"295897","properties":[{"key":"Description","value":"-"}],"isoformId":"A2AWL7-2"},{"database":"ProteomicsDB","id":"295898","properties":[{"key":"Description","value":"-"}],"isoformId":"A2AWL7-3"},{"database":"ProteomicsDB","id":"295899","properties":[{"key":"Description","value":"-"}],"isoformId":"A2AWL7-4"},{"database":"Pumba","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"6067","properties":[{"key":"antibodies","value":"88 antibodies from 16 providers"}]},{"database":"DNASU","id":"29808","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENSMUST00000046717.13","properties":[{"key":"ProteinId","value":"ENSMUSP00000043795.7"},{"key":"GeneId","value":"ENSMUSG00000033943.16"}],"isoformId":"A2AWL7-1"},{"database":"Ensembl","id":"ENSMUST00000110773.9","properties":[{"key":"ProteinId","value":"ENSMUSP00000106400.3"},{"key":"GeneId","value":"ENSMUSG00000033943.16"}],"isoformId":"A2AWL7-3"},{"database":"Ensembl","id":"ENSMUST00000156510.2","properties":[{"key":"ProteinId","value":"ENSMUSP00000119044.2"},{"key":"GeneId","value":"ENSMUSG00000033943.16"}],"isoformId":"A2AWL7-2"},{"database":"GeneID","id":"29808","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc008lur.1","properties":[{"key":"OrganismName","value":"mouse"}],"isoformId":"A2AWL7-4"},{"database":"AGR","id":"MGI:1352483","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"23269","properties":[{"key":"Description","value":"-"}]},{"database":"MGI","id":"MGI:1352483","properties":[{"key":"GeneName","value":"Mga"}]},{"database":"VEuPathDB","id":"HostDB:ENSMUSG00000033943","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG3585","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00940000156269","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_000469_1_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"6119313at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-MMU-8953750","properties":[{"key":"PathwayName","value":"Transcriptional Regulation by E2F6"}]},{"database":"BioGRID-ORCS","id":"29808","properties":[{"key":"hits","value":"9 hits in 82 CRISPR screens"}]},{"database":"PRO","id":"PR:A2AWL7","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000589","properties":[{"key":"Component","value":"Chromosome 2"}]},{"database":"RNAct","id":"A2AWL7","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSMUSG00000033943","properties":[{"key":"ExpressionPatterns","value":"Expressed in undifferentiated genital tubercle and 249 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"A2AWL7","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0000785","properties":[{"key":"GoTerm","value":"C:chromatin"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0071339","properties":[{"key":"GoTerm","value":"C:MLL1 complex"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0090571","properties":[{"key":"GoTerm","value":"C:RNA polymerase II transcription repressor complex"},{"key":"GoEvidenceType","value":"ISO:GO_Central"}]},{"database":"GO","id":"GO:0005667","properties":[{"key":"GoTerm","value":"C:transcription regulator complex"},{"key":"GoEvidenceType","value":"IDA:MGI"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"10601024"}]},{"database":"GO","id":"GO:0001228","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription activator activity, RNA polymerase II-specific"},{"key":"GoEvidenceType","value":"IDA:NTNU_SB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"10601024"}]},{"database":"GO","id":"GO:0003700","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription factor activity"},{"key":"GoEvidenceType","value":"TAS:MGI"}],"evidences":[{"evidenceCode":"ECO:0000304","source":"PubMed","id":"10601024"}]},{"database":"GO","id":"GO:0000981","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription factor activity, RNA polymerase II-specific"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0046983","properties":[{"key":"GoTerm","value":"F:protein dimerization activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0000978","properties":[{"key":"GoTerm","value":"F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0000977","properties":[{"key":"GoTerm","value":"F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"},{"key":"GoEvidenceType","value":"IDA:NTNU_SB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"10601024"}]},{"database":"GO","id":"GO:0001708","properties":[{"key":"GoTerm","value":"P:cell fate specification"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:1990830","properties":[{"key":"GoTerm","value":"P:cellular response to leukemia inhibitory factor"},{"key":"GoEvidenceType","value":"IEP:MGI"}],"evidences":[{"evidenceCode":"ECO:0000270","source":"PubMed","id":"20439489"}]},{"database":"GO","id":"GO:0045944","properties":[{"key":"GoTerm","value":"P:positive regulation of transcription by RNA polymerase II"},{"key":"GoEvidenceType","value":"IDA:NTNU_SB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"10601024"}]},{"database":"GO","id":"GO:0006357","properties":[{"key":"GoTerm","value":"P:regulation of transcription by RNA polymerase II"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"CDD","id":"cd18911","properties":[{"key":"EntryName","value":"bHLHzip_MGA"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd20195","properties":[{"key":"EntryName","value":"T-box_MGA-like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.60.40.820:FF:000009","properties":[{"key":"EntryName","value":"MAX gene-associated protein isoform X1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"4.10.280.10:FF:000040","properties":[{"key":"EntryName","value":"MAX gene-associated protein isoform X1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"4.10.280.10","properties":[{"key":"EntryName","value":"Helix-loop-helix DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.60.40.820","properties":[{"key":"EntryName","value":"Transcription factor, T-box"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011598","properties":[{"key":"EntryName","value":"bHLH_dom"}]},{"database":"InterPro","id":"IPR036638","properties":[{"key":"EntryName","value":"HLH_DNA-bd_sf"}]},{"database":"InterPro","id":"IPR037935","properties":[{"key":"EntryName","value":"MAX_gene-associated_bHLHzip"}]},{"database":"InterPro","id":"IPR032060","properties":[{"key":"EntryName","value":"MGA_dom"}]},{"database":"InterPro","id":"IPR008967","properties":[{"key":"EntryName","value":"p53-like_TF_DNA-bd_sf"}]},{"database":"InterPro","id":"IPR046360","properties":[{"key":"EntryName","value":"T-box_DNA-bd"}]},{"database":"InterPro","id":"IPR036960","properties":[{"key":"EntryName","value":"T-box_sf"}]},{"database":"InterPro","id":"IPR001699","properties":[{"key":"EntryName","value":"TF_T-box"}]},{"database":"InterPro","id":"IPR018186","properties":[{"key":"EntryName","value":"TF_T-box_CS"}]},{"database":"PANTHER","id":"PTHR11267:SF32","properties":[{"key":"EntryName","value":"MAX GENE-ASSOCIATED PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11267","properties":[{"key":"EntryName","value":"T-BOX PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00010","properties":[{"key":"EntryName","value":"HLH"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF16059","properties":[{"key":"EntryName","value":"MGA_dom"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00907","properties":[{"key":"EntryName","value":"T-box"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00937","properties":[{"key":"EntryName","value":"TBOX"}]},{"database":"SMART","id":"SM00353","properties":[{"key":"EntryName","value":"HLH"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00425","properties":[{"key":"EntryName","value":"TBOX"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF47459","properties":[{"key":"EntryName","value":"HLH, helix-loop-helix DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF49417","properties":[{"key":"EntryName","value":"p53-like transcription factors"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50888","properties":[{"key":"EntryName","value":"BHLH"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS01264","properties":[{"key":"EntryName","value":"TBOX_2"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50252","properties":[{"key":"EntryName","value":"TBOX_3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MEEKQQIILANQDGGTVTGGAPTFFVILKQPGNGKTDQGILVTNRDARALLSRESSPGKSKEKICLPADCTVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDSHRYKWNGRWWEPSGKAEPHILGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVPAEKATEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLSSKPQREGKQRNSSDQEGNSVSSSPAHRVRLTEGEGSEIHSGDFDPVLRGHEASSLSLEKAPHNVKQDFLGFMNTDSTHEVPQLKHEISESRIVNSFEDDSQISSPSNPNGNFNVVIKEEPLDDYDYELGECPEGITVKQEETDEETDVYSNSDDDPILEKQLKRHNKVDNLEADHPSYKWLPNSPGVAKAKMFKLDAGKMPVVYLEPCAVTKSTVKISELPDNMLSTSRKDKSMLAELEYLPAYIENSDGTDFCLSKDSENSLRKHSPDLRIVQKYTLLKEPNWKYPDILDNSSTERIHDSSKGSTAESFSGKEDLGKKRTTMLKMAIPSKTVTASHSASPNTPGKRGRPRKLRLSKAGRPPKNTGKSLTAAKNIPVGPGSTFPDVKPDLEDVDGVLFVSFESKEALDIHAVDGTTEEPSSLQTTTTNDSGCRTRISQLEKELIEDLKSLRHKQVIHPALQEVGLKLNSVDPTVSIDLKYLGVQLPLAPATSFPLWNVTGTNPASPDAGFPFVSRTGKTNDFTKIKGWRGKFQNASASRNEGGNSEASLKNRSAFCSDKLDEYLENEGKLMETNIGFSSNAPTSPVVYQLPTKSTSYVRTLDSVLKKQSTISPSTSHSVKPQSVTTASRKTKAQNKQTTLSGRTKSSYKSILPYPVSPKQKNSHVSQGDKITKNSLSSTSDNQVTNLVVPSVDENAFPKQISLRQAQQQHLQQQGTRPPGLSKSQVKLMDLEDCALWEGKPRTYITEERADVSLTTLLTAQASLKTKPIHTIIRKRAPPCNNDFCRLGCVCSSLALEKRQPAHCRRPDCMFGCTCLKRKVVLVKGGSKTKHFHKKAANRDPLFYDTLGEEGREGGGVREDEEQLKEKKKRKKLEYTVCEAEPEQPVRHYPLWVKVEGEVDPEPVYIPTPSVIEPIKPLVLPQPDLSSTTKGKLTPGIKPARTYTPKPNPVIREEDKDPVYLYFESMMTCARVRVYERKKEEQRQLSPPLSPSSSFQQQSSCYSSPENRVTKELDSEQTLKQLICDLEDDSDKSQEKSWKSSCNEGESSSTSYVHQRSPGGPTKLIEIISDCNWEEDRNKILSILSQHINSNMPQSLKVGSFIIELASQRKCRGEKTPPVYSSRVKISMPSSQDQDDMAEKSGSETPDGPLSPGKMDDISPVQTDALDSVRERLHGGKGLPFYAGLSPSGKLVAYKRKPSSTTSGLIQVASNAKVAASRKPRTLLPSTSNSKMASSGPATNRSGKNLKAFVPAKRPIAARPSPGGVFTQFVMSKVGALQQKIPGVRTPQPLTGPQKFSIRPSPVMVVTPVVSSEQVQVCSTVAAAVTTSPQVFLENVTAVPSLTANSDMGAKEATYSSSASTAGVVEISETNNTTLVTSTQSTATVNLTKTTGITTSPVASVSFAKPLVASPTITLPVASTASTSIVMVTTAASSSVVTTPTSSLSSVPIILSGINGSPPVSQRPENAPQIPVTTPQISSNNVKRTGPRLLHPNGQIVQLLPLHQIRGSNAQPSLQPVVFRNPGSMVGIRLPAPCKSSETPSSSASSSAFSVMSPVIQAVGSSPTVNVISQAPSLLSSGSSFVSQAGTLTLRISPPETQNLASKTGSESKITPSTGGQPVGTASLIPLQSGSFALLQLPGQKPIPSSVLQHVASLQIKKESQSTDQKDETNSIKREEETKKALPSKDKALDSEANIMKQNSGIIASENTSNNSLDDGGDLLDEETLREDARPYEYSYSTGSHTDEDKDGDEDSGNKNQNSPKEKQTVPEVRAGSKNIDIMALQSIRSIRPQKCVKVKVEPQEGSDNPENPDDFLVLSKDSKFELSGNQVKEQQSNSQAEAKKDCEDSLGKDSLRERWRKHLKGPLTQKYIGISQNFNKEANVQFFTEMKPCQENSEQDISELLGKSGTIESGGVLKTEDGSWSGISSSAAFSIIPRRATKGRRGSRHFQGHLLLPREQMKPKQQTKDGRSSAADFTVLDLEDEDEEDEKTDDSLDEIVDVVSGYQSEEVDVEKNNYVDYLEDDEQVDVETIEELSEEINFPYKKTTATHTQSFKQQCHSHISADEKASEKSRKVSLISSKLKDDCWGDKPHKETEAFAYYRRTHTANERRRRGEMRDLFEKLKITLGLLHSSKVSKSLILNRAFSEIQGLTDQADKLIGQKNLLSRKRSILIRKVSSLSGKTEEVVLKKLEYIYAKQQALEAQKRKKKLGSDEFCVSPRIGTQLEGSSASSVDLGQMLMNNRRGKPLILSRKRDQATENASPSDTPHSSANLVMTPQGQLLTLKGPLFSGPVVAVSPALLEGGLKPQVASSTMSQSENDDLFMMPRIVNVTSLAAEEDLGGMSGNKYRHEVPDGKPLDHLRDIAGSEASSLKDTERISSRGNHRDSRKALGPTQVLLANKDSGFPHVADVSTMQAAQEFIPKNMSGDVRGHRYKWKECELRGERLKSKESQFHKLKMKDLKDSSIEMELRKVASAIEEAALHPSELLTNMEDEDDTDETLTSLLNEIAFLNQQLNDDSGLAELSGSMDTEFSGDAQRAFISKLAPGNRSAFQVGHLGAGVKELPDVQEESESISPLLLHLEDDDFSENEKQLGDTASEPDVLKIVIDPEIKDSLVSHRKSSDGGQSTSGLPAEPESVSSPPILHMKTGPENSNTDTLWRPMPKLAPLGLKVANPPSDADGQSLKVMPALAPIAAKVGSIGHKMNLAGIDQEGRGSKVMPTLAPVVPKLGNSGAPSSSSGK","length":3003,"molWeight":328802,"crc64":"C0963FF86506A75C","md5":"770AFA59CDEC247891CC35540C8E76CB"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"ALTERNATIVE PRODUCTS":4,"TISSUE SPECIFICITY":1,"DEVELOPMENTAL STAGE":1,"DOMAIN":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Domain":1,"DNA binding":1,"Region":20,"Compositional bias":19,"Modified residue":10,"Cross-link":41,"Alternative sequence":7,"Sequence conflict":40},"uniParcId":"UPI0000566A42"}}