{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"A2AGB2","uniProtkbId":"CA087_MOUSE","entryAudit":{"firstPublicDate":"2007-04-17","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2007-02-20","entryVersion":105,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Mus musculus","commonName":"Mouse","taxonId":10090,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Glires","Rodentia","Myomorpha","Muroidea","Muridae","Murinae","Mus","Mus"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein C1orf87 homolog"}}},"genes":[{"geneName":{"value":"Gm12695"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8N0U7"}],"value":"Cell projection, cilium","id":"SL-0066"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8N0U7"}],"value":"Cytoplasm, cytoskeleton, cilium axoneme","id":"SL-0304"}}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":545,"modifier":"EXACT"}},"description":"Uncharacterized protein C1orf87 homolog","featureId":"PRO_0000284490"},{"type":"Region","location":{"start":{"value":34,"modifier":"EXACT"},"end":{"value":98,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":269,"modifier":"EXACT"},"end":{"value":296,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":415,"modifier":"EXACT"},"end":{"value":444,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":34,"modifier":"EXACT"},"end":{"value":44,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":53,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":69,"modifier":"EXACT"},"end":{"value":78,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":415,"modifier":"EXACT"},"end":{"value":428,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":429,"modifier":"EXACT"},"end":{"value":441,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-0966","category":"Cellular component","name":"Cell projection"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0206","category":"Cellular component","name":"Cytoskeleton"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"19468303","citationType":"journal article","authors":["Church D.M.","Goodstadt L.","Hillier L.W.","Zody M.C.","Goldstein S.","She X.","Bult C.J.","Agarwala R.","Cherry J.L.","DiCuccio M.","Hlavina W.","Kapustin Y.","Meric P.","Maglott D.","Birtle Z.","Marques A.C.","Graves T.","Zhou S.","Teague B.","Potamousis K.","Churas C.","Place M.","Herschleb J.","Runnheim R.","Forrest D.","Amos-Landgraf J.","Schwartz D.C.","Cheng Z.","Lindblad-Toh K.","Eichler E.E.","Ponting C.P."],"citationCrossReferences":[{"database":"PubMed","id":"19468303"},{"database":"DOI","id":"10.1371/journal.pbio.1000112"}],"title":"Lineage-specific biology revealed by a finished genome assembly of the mouse.","publicationDate":"2009","journal":"PLoS Biol.","firstPage":"E1000112","lastPage":"E1000112","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AL683816","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL772139","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"CCDS","id":"CCDS38815.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_001074753.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001081284.2"}]},{"database":"AlphaFoldDB","id":"A2AGB2","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"A2AGB2","properties":[{"key":"Number of interactors","value":"2"}]},{"database":"STRING","id":"10090.ENSMUSP00000102686","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"A2AGB2","properties":[{"key":"glycosylation","value":"1 site"}]},{"database":"iPTMnet","id":"A2AGB2","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"A2AGB2","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"10090-ENSMUSP00000102686","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"281721","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"33284","properties":[{"key":"antibodies","value":"76 antibodies from 13 providers"}]},{"database":"Ensembl","id":"ENSMUST00000107071.2","properties":[{"key":"ProteinId","value":"ENSMUSP00000102686.2"},{"key":"GeneId","value":"ENSMUSG00000078639.2"}]},{"database":"GeneID","id":"620779","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"mmu:620779","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc008ttm.1","properties":[{"key":"OrganismName","value":"mouse"}]},{"database":"AGR","id":"MGI:3650206","properties":[{"key":"Description","value":"-"}]},{"database":"MGI","id":"MGI:3650206","properties":[{"key":"GeneName","value":"Gm12695"}]},{"database":"VEuPathDB","id":"HostDB:ENSMUSG00000078639","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502RIAR","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000008678","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_040182_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"A2AGB2","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"YVHGIPR","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"9989690at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"A2AGB2","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID-ORCS","id":"620779","properties":[{"key":"hits","value":"2 hits in 71 CRISPR screens"}]},{"database":"PRO","id":"PR:A2AGB2","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000589","properties":[{"key":"Component","value":"Chromosome 4"}]},{"database":"RNAct","id":"A2AGB2","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSMUSG00000078639","properties":[{"key":"ExpressionPatterns","value":"Expressed in spermatid and 7 other cell types or tissues"}]},{"database":"GO","id":"GO:0005930","properties":[{"key":"GoTerm","value":"C:axoneme"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0005929","properties":[{"key":"GoTerm","value":"C:cilium"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"InterPro","id":"IPR040774","properties":[{"key":"EntryName","value":"DUF5580"}]},{"database":"InterPro","id":"IPR049247","properties":[{"key":"EntryName","value":"DUF5580_C"}]},{"database":"InterPro","id":"IPR049246","properties":[{"key":"EntryName","value":"DUF5580_M"}]},{"database":"InterPro","id":"IPR048316","properties":[{"key":"EntryName","value":"DUF5580_N"}]},{"database":"InterPro","id":"IPR011992","properties":[{"key":"EntryName","value":"EF-hand-dom_pair"}]},{"database":"PANTHER","id":"PTHR34830:SF1","properties":[{"key":"EntryName","value":"GENE 12695-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR34830","properties":[{"key":"EntryName","value":"SIMILAR TO HYPOTHETICAL PROTEIN MGC34837"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF17743","properties":[{"key":"EntryName","value":"DUF5580"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF20743","properties":[{"key":"EntryName","value":"DUF5580_C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF20742","properties":[{"key":"EntryName","value":"DUF5580_M"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF47473","properties":[{"key":"EntryName","value":"EF-hand"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSSPWKTSQSSVPMPEMIVKIVGSKHFRYFIEKPMNKQNEKLKTEPQTSLQKPRNDYSRRVSRDLPGPTDSSEQQITANPAEKEESKHQRSSLKPESNQKFLTRVFSNRFLDGRISYEANVHCSSVPTGDQSLSYMHSLPRRKSVGWCLEHTAKDSSGQAEEIVQRPSVMTREDSFLTTLVRRELNSRPLSSNLLDKLQKELKTLDPISSGFLHQSQLSCLFLRHKVPLPLLTVKLLCQRFSRRCSPEMVNYGEVLCFLKEATKDNLQQNGTAGYSNSRKTSSPSYHKQSIPPQDSSLLSEVNKSLLEILKMALRPCQGKLSIDCLNMSFRKEDHSFSGCLPLPKVISICSKHGLYVTMTLLETLLHHQELGYRGEIKWKNFVKWLNRASADLSCDMPAGKNKKETQGDLVDIPERPQRKTEHVKTPEENLQTKNPTTMTSAPEDPVTFFKNRPVSQPVEHLAVKKDGQSELWIDRFRKLENALYLCDLSNTGVLERERARRLIHNYNLIYSLSLSPRRINQALQRYRSGENIILEPALQYLKEL","length":545,"molWeight":62440,"crc64":"FB0BAFF53A87CDFB","md5":"1423E62FAC58E9DD668CB03D6292EA44"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Chain":1,"Region":3,"Compositional bias":5},"uniParcId":"UPI0000194DE4"}}