{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"A0A384E126","uniProtkbId":"ATZG_PSESD","entryAudit":{"firstPublicDate":"2019-05-08","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"2018-11-07","entryVersion":18,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudomonas sp. (strain ADP)","taxonId":47660,"evidences":[{"evidenceCode":"ECO:0000312","source":"PDB","id":"6C62"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Pseudomonadales","Pseudomonadaceae","Pseudomonas"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"29523689"}],"value":"1-carboxybiuret hydrolase subunit AtzG"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"29523689"}],"value":"atzG"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"29523689"}],"value":"Important for the activity of the AtzE subunit of 1-carboxybiuret hydrolase"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"11544232"}],"value":"Xenobiotic degradation; atrazine degradation"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"29523689"}],"value":"Heterotetramer consisting of 2 AtzE and 2 AtzG subunits"}],"commentType":"SUBUNIT"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"1-carboxybiuret hydrolase subunit AtzG","featureId":"PRO_0000447020"},{"type":"Helix","location":{"start":{"value":3,"modifier":"EXACT"},"end":{"value":17,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"6C62"}]},{"type":"Helix","location":{"start":{"value":23,"modifier":"EXACT"},"end":{"value":44,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"6C62"}]},{"type":"Helix","location":{"start":{"value":62,"modifier":"EXACT"},"end":{"value":65,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"6C62"}]}],"geneLocations":[{"value":"pADP-1","geneEncodingType":"Plasmid"}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0614","category":"Technical term","name":"Plasmid"}],"references":[{"referenceNumber":1,"citation":{"id":"11544232","citationType":"journal article","authors":["Martinez B.","Tomkins J.","Wackett L.P.","Wing R.","Sadowsky M.J."],"citationCrossReferences":[{"database":"PubMed","id":"11544232"},{"database":"DOI","id":"10.1128/jb.183.19.5684-5697.2001"}],"title":"Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. strain ADP.","publicationDate":"2001","journal":"J. Bacteriol.","firstPage":"5684","lastPage":"5697","volume":"183"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ADP","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"29523689","citationType":"journal article","authors":["Esquirol L.","Peat T.S.","Wilding M.","Liu J.W.","French N.G.","Hartley C.J.","Onagi H.","Nebl T.","Easton C.J.","Newman J.","Scott C."],"citationCrossReferences":[{"database":"PubMed","id":"29523689"},{"database":"DOI","id":"10.1074/jbc.ra118.001996"}],"title":"An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme.","publicationDate":"2018","journal":"J. Biol. Chem.","firstPage":"7880","lastPage":"7891","volume":"293"},"referencePositions":["X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN COMPLEX WITH ATZE","FUNCTION","SUBUNIT","IDENTIFICATION BY MASS SPECTROMETRY"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U66917","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_082996223.1","properties":[{"key":"NucleotideSequenceId","value":"NC_004956.1"}]},{"database":"PDB","id":"6C62","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"1.95 A"},{"key":"Chains","value":"C/D=1-68"}]},{"database":"PDB","id":"6C6G","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.10 A"},{"key":"Chains","value":"C/D=1-68"}]},{"database":"PDBsum","id":"6C62","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"6C6G","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"A0A384E126","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A384E126","properties":[{"key":"Description","value":"-"}]},{"database":"BRENDA","id":"3.5.1.131","properties":[{"key":"OrganismId","value":"14885"}]},{"database":"SABIO-RK","id":"A0A384E126","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00008","properties":[{"key":"RectionId","value":"-"}]},{"database":"GO","id":"GO:0019381","properties":[{"key":"GoTerm","value":"P:atrazine catabolic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniPathway"}]},{"database":"InterPro","id":"IPR025148","properties":[{"key":"EntryName","value":"AtzG-like"}]},{"database":"Pfam","id":"PF13318","properties":[{"key":"EntryName","value":"AtzG-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTETEIFAYIEAASIAIGIPLEPARARAVAHHFSRTALLAEMLESVPLSPESELAEIYRPAPFPAEDI","length":68,"molWeight":7422,"crc64":"B9D22A3BCFCDC4D7","md5":"07AB2BD980320468BE104ED75210C033"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"PATHWAY":1,"SUBUNIT":1},"countByFeatureType":{"Chain":1,"Helix":3},"uniParcId":"UPI0009F69F61"}}