##gff-version 3
Q9Y6J6	UniProtKB	Chain	1	123	.	.	.	ID=PRO_0000144285;Note=Potassium voltage-gated channel subfamily E member 2	
Q9Y6J6	UniProtKB	Transmembrane	49	69	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9Y6J6	UniProtKB	Topological domain	70	123	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9Y6J6	UniProtKB	Glycosylation	6	6	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9Y6J6	UniProtKB	Glycosylation	29	29	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9Y6J6	UniProtKB	Natural variant	8	8	.	.	.	ID=VAR_008375;Note=T->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10219239,ECO:0000269|PubMed:16922724;Dbxref=dbSNP:rs2234916,PMID:10219239,PMID:16922724	
Q9Y6J6	UniProtKB	Natural variant	8	8	.	.	.	ID=VAR_037794;Note=T->I;Dbxref=dbSNP:rs35759083	
Q9Y6J6	UniProtKB	Natural variant	9	9	.	.	.	ID=VAR_008376;Note=Risk factor for drug-induced arrhythmia%3B impedes activation and increases sensitivity to macrolide antibiotics%3B may lower current in KCNQ1/KCNE2 channel. Q->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10219239;Dbxref=dbSNP:rs16991652,PMID:10219239	
Q9Y6J6	UniProtKB	Natural variant	14	14	.	.	.	ID=VAR_074921;Note=In LQT6%3B uncertain significance. V->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs142153692,PMID:19716085	
Q9Y6J6	UniProtKB	Natural variant	20	20	.	.	.	ID=VAR_074922;Note=In LQT6%3B uncertain significance. I->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs199473363,PMID:19716085	
Q9Y6J6	UniProtKB	Natural variant	27	27	.	.	.	ID=VAR_037795;Note=In ATFB4%3B gain-of-function mutation associated with the initiation and/or maintenance of AF. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15368194;Dbxref=dbSNP:rs74315449,PMID:15368194	
Q9Y6J6	UniProtKB	Natural variant	27	27	.	.	.	ID=VAR_074923;Note=In LQT6%3B uncertain significance. R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs148968498,PMID:19716085	
Q9Y6J6	UniProtKB	Natural variant	54	54	.	.	.	ID=VAR_008377;Note=In LQT6%3B forms I(KR) channels that deactivate twice as fast as wild type. M->T;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10219239,ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs74315447,PMID:10219239,PMID:19716085	
Q9Y6J6	UniProtKB	Natural variant	57	57	.	.	.	ID=VAR_008378;Note=In LQT6%3B may affect KCNQ1/KCNE2 channel. I->T;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10219239,ECO:0000269|PubMed:16922724,ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs74315448,PMID:10219239,PMID:16922724,PMID:19716085	
Q9Y6J6	UniProtKB	Natural variant	60	60	.	.	.	ID=VAR_029334;Note=In LQT6%3B uncertain significance. F->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16922724;Dbxref=dbSNP:rs16991654,PMID:16922724	
Q9Y6J6	UniProtKB	Natural variant	65	65	.	.	.	ID=VAR_074924;Note=In LQT6%3B uncertain significance. V->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs199473364,PMID:19716085	
Q9Y6J6	UniProtKB	Natural variant	65	65	.	.	.	ID=VAR_015063;Note=In LQT6. V->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12185453;Dbxref=dbSNP:rs199473364,PMID:12185453	
Q9Y6J6	UniProtKB	Natural variant	66	66	.	.	.	ID=VAR_022052;Note=A->V;Dbxref=dbSNP:rs16991656	
Q9Y6J6	UniProtKB	Natural variant	77	77	.	.	.	ID=VAR_074925;Note=In LQT6%3B uncertain significance. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs199473365,PMID:19716085	
Q9Y6J6	UniProtKB	Natural variant	77	77	.	.	.	ID=VAR_035386;Note=In LQT6. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16922724;Dbxref=dbSNP:rs141423405,PMID:16922724	
Q9Y6J6	UniProtKB	Natural variant	94	94	.	.	.	ID=VAR_074926;Note=In LQT6%3B uncertain significance. E->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19716085;Dbxref=dbSNP:rs74424227,PMID:19716085	
Q9Y6J6	UniProtKB	Mutagenesis	75	75	.	.	.	Note=Increases tail current in KCNH2/KCNE2 channel. K->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11874988;Dbxref=PMID:11874988	
Q9Y6J6	UniProtKB	Helix	3	38	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2M0Q	
Q9Y6J6	UniProtKB	Helix	46	74	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2M0Q	
Q9Y6J6	UniProtKB	Helix	88	114	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2M0Q