##gff-version 3
Q9VUQ5	UniProtKB	Chain	1	1214	.	.	.	ID=PRO_0000194071;Note=Protein argonaute-2	
Q9VUQ5	UniProtKB	Domain	608	717	.	.	.	Note=PAZ;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00142	
Q9VUQ5	UniProtKB	Domain	885	1186	.	.	.	Note=Piwi;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00150	
Q9VUQ5	UniProtKB	Region	1	412	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Region	681	686	.	.	.	Note=Interaction with guide RNA;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9VUQ5	UniProtKB	Region	1075	1076	.	.	.	Note=Interaction with guide RNA;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9VUQ5	UniProtKB	Region	1119	1127	.	.	.	Note=Interaction with guide RNA;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9VUQ5	UniProtKB	Region	1156	1178	.	.	.	Note=Interaction with guide RNA;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9VUQ5	UniProtKB	Compositional bias	18	93	.	.	.	Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	107	117	.	.	.	Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	118	131	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	141	154	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	164	177	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	187	200	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	210	223	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	233	246	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	256	269	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	270	282	.	.	.	Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	302	315	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	325	338	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	348	361	.	.	.	Note=Gly residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Compositional bias	362	394	.	.	.	Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9VUQ5	UniProtKB	Binding site	965	965	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q9VUQ5	UniProtKB	Binding site	1037	1037	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q9VUQ5	UniProtKB	Binding site	1173	1173	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q9VUQ5	UniProtKB	Alternative sequence	1	6	.	.	.	ID=VSP_050781;Note=In isoform C. MGKKDK->MHFPITTPE;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.3	
Q9VUQ5	UniProtKB	Natural variant	714	714	.	.	.	Note=In strain: 186. S->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16546082;Dbxref=PMID:16546082	
Q9VUQ5	UniProtKB	Natural variant	740	740	.	.	.	Note=In strain: 130. S->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16546082;Dbxref=PMID:16546082	
Q9VUQ5	UniProtKB	Natural variant	783	783	.	.	.	Note=In strain: 138%2C 140 and 196. S->N;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12537569,ECO:0000269|PubMed:16546082;Dbxref=PMID:12537569,PMID:16546082	
Q9VUQ5	UniProtKB	Natural variant	835	835	.	.	.	Note=In strain: 128%2C 130%2C 138%2C 140%2C 141%2C 186%2C 187 and 196. T->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12537569,ECO:0000269|PubMed:16546082;Dbxref=PMID:12537569,PMID:16546082	
Q9VUQ5	UniProtKB	Natural variant	854	854	.	.	.	Note=In strain: 128%2C 130%2C 138%2C 140%2C 141%2C 186%2C 187 and 196. S->T;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12537569,ECO:0000269|PubMed:16546082;Dbxref=PMID:12537569,PMID:16546082	
Q9VUQ5	UniProtKB	Natural variant	866	866	.	.	.	Note=In strain: 128%2C 130%2C 141%2C 186 and 187. D->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16546082;Dbxref=PMID:16546082	
Q9VUQ5	UniProtKB	Mutagenesis	966	966	.	.	.	Note=Impaired conversion of the pre-RISC complex%2C containing duplex siRNA%2C to the holo-RISC complex%2C containing single-stranded guide siRNA. V->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32504809;Dbxref=PMID:32504809	
Q9VUQ5	UniProtKB	Sequence conflict	201	201	.	.	.	Note=G->D;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9VUQ5	UniProtKB	Beta strand	601	603	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Helix	604	611	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	618	621	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1VYN	
Q9VUQ5	UniProtKB	Helix	623	625	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Helix	627	634	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	638	641	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Helix	645	647	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	652	655	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	658	663	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Turn	664	666	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	668	677	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Helix	678	683	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Turn	684	686	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	692	698	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	705	708	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1T2R	
Q9VUQ5	UniProtKB	Helix	710	712	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Beta strand	713	716	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3MJ0	
Q9VUQ5	UniProtKB	Turn	717	719	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1T2R