##gff-version 3 Q9UKZ4 UniProtKB Chain 1 2725 . . . ID=PRO_0000259498;Note=Teneurin-1 Q9UKZ4 UniProtKB Chain 2596 2725 . . . ID=PRO_0000421006;Note=Teneurin C-terminal-associated peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9UKZ4 UniProtKB Topological domain 1 324 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Transmembrane 325 345 . . . Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Topological domain 346 2725 . . . Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Domain 1 318 . . . Note=Teneurin N-terminal;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00694 Q9UKZ4 UniProtKB Domain 528 559 . . . Note=EGF-like 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Domain 560 591 . . . Note=EGF-like 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Domain 592 624 . . . Note=EGF-like 3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Domain 625 657 . . . Note=EGF-like 4;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Domain 658 691 . . . Note=EGF-like 5;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Domain 692 721 . . . Note=EGF-like 6;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Domain 722 753 . . . Note=EGF-like 7;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Domain 761 796 . . . Note=EGF-like 8;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Repeat 1194 1219 . . . Note=NHL 1 Q9UKZ4 UniProtKB Repeat 1292 1336 . . . Note=NHL 2 Q9UKZ4 UniProtKB Repeat 1351 1402 . . . Note=NHL 3 Q9UKZ4 UniProtKB Repeat 1414 1458 . . . Note=NHL 4 Q9UKZ4 UniProtKB Repeat 1481 1524 . . . Note=NHL 5 Q9UKZ4 UniProtKB Repeat 1534 1553 . . . Note=YD 1 Q9UKZ4 UniProtKB Repeat 1570 1590 . . . Note=YD 2 Q9UKZ4 UniProtKB Repeat 1608 1632 . . . Note=YD 3 Q9UKZ4 UniProtKB Repeat 1633 1654 . . . Note=YD 4 Q9UKZ4 UniProtKB Repeat 1655 1675 . . . Note=YD 5 Q9UKZ4 UniProtKB Repeat 1845 1864 . . . Note=YD 6 Q9UKZ4 UniProtKB Repeat 1865 1885 . . . Note=YD 7 Q9UKZ4 UniProtKB Repeat 1886 1904 . . . Note=YD 8 Q9UKZ4 UniProtKB Repeat 1905 1925 . . . Note=YD 9 Q9UKZ4 UniProtKB Repeat 1933 1949 . . . Note=YD 10 Q9UKZ4 UniProtKB Repeat 1950 1969 . . . Note=YD 11 Q9UKZ4 UniProtKB Repeat 1970 1989 . . . Note=YD 12 Q9UKZ4 UniProtKB Repeat 1992 2012 . . . Note=YD 13 Q9UKZ4 UniProtKB Repeat 2015 2035 . . . Note=YD 14 Q9UKZ4 UniProtKB Repeat 2085 2105 . . . Note=YD 15 Q9UKZ4 UniProtKB Repeat 2113 2133 . . . Note=YD 16 Q9UKZ4 UniProtKB Repeat 2153 2173 . . . Note=YD 17 Q9UKZ4 UniProtKB Repeat 2174 2194 . . . Note=YD 18 Q9UKZ4 UniProtKB Repeat 2196 2216 . . . Note=YD 19 Q9UKZ4 UniProtKB Repeat 2228 2248 . . . Note=YD 20 Q9UKZ4 UniProtKB Repeat 2250 2270 . . . Note=YD 21 Q9UKZ4 UniProtKB Repeat 2296 2313 . . . Note=YD 22 Q9UKZ4 UniProtKB Repeat 2314 2337 . . . Note=YD 23 Q9UKZ4 UniProtKB Region 1 48 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9UKZ4 UniProtKB Region 174 241 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9UKZ4 UniProtKB Motif 62 65 . . . Note=Nuclear localization signal (NLS);Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9UKZ4 UniProtKB Motif 290 297 . . . Note=Required for interaction with SORBS1 (Ten-1 ICD form);Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9UKZ4 UniProtKB Compositional bias 174 189 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9UKZ4 UniProtKB Compositional bias 192 201 . . . Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9UKZ4 UniProtKB Site 2595 2596 . . . Note=Cleavage;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Modified residue 105 105 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WTS4 Q9UKZ4 UniProtKB Modified residue 109 109 . . . Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WTS4 Q9UKZ4 UniProtKB Modified residue 116 116 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WTS4 Q9UKZ4 UniProtKB Modified residue 2580 2580 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18669648;Dbxref=PMID:18669648 Q9UKZ4 UniProtKB Glycosylation 433 433 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 905 905 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1084 1084 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1550 1550 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1567 1567 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1663 1663 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1699 1699 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1757 1757 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1781 1781 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 1842 1842 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 2145 2145 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 2285 2285 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Glycosylation 2602 2602 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9UKZ4 UniProtKB Disulfide bond 532 542 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 536 547 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 549 558 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 567 578 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 580 589 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 596 607 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 601 612 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 614 623 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 628 639 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 633 644 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 646 655 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 666 679 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 681 690 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 695 705 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 699 710 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 712 721 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 726 736 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 730 741 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 743 752 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 765 775 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 769 784 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Disulfide bond 786 795 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9UKZ4 UniProtKB Alternative sequence 1231 1231 . . . ID=VSP_043356;Note=In isoform 2. L->LRNRDTRH;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 Q9UKZ4 UniProtKB Natural variant 40 40 . . . ID=VAR_053792;Note=Y->H;Dbxref=dbSNP:rs36065191 Q9UKZ4 UniProtKB Natural variant 174 174 . . . ID=VAR_076255;Note=A->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23092983;Dbxref=dbSNP:rs139486546,PMID:23092983 Q9UKZ4 UniProtKB Natural variant 342 342 . . . ID=VAR_036596;Note=In a breast cancer sample%3B somatic mutation. L->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16959974;Dbxref=PMID:16959974 Q9UKZ4 UniProtKB Natural variant 371 371 . . . ID=VAR_053793;Note=M->T;Dbxref=dbSNP:rs2213591 Q9UKZ4 UniProtKB Natural variant 632 632 . . . ID=VAR_053794;Note=M->V;Dbxref=dbSNP:rs16999334 Q9UKZ4 UniProtKB Natural variant 641 641 . . . ID=VAR_053795;Note=K->E;Dbxref=dbSNP:rs6649271 Q9UKZ4 UniProtKB Natural variant 1216 1216 . . . ID=VAR_036597;Note=In a breast cancer sample%3B somatic mutation. V->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16959974;Dbxref=dbSNP:rs137882910,PMID:16959974 Q9UKZ4 UniProtKB Natural variant 1482 1482 . . . ID=VAR_036598;Note=In a colorectal cancer sample%3B somatic mutation. F->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16959974;Dbxref=PMID:16959974 Q9UKZ4 UniProtKB Natural variant 2235 2235 . . . ID=VAR_036599;Note=In a breast cancer sample%3B somatic mutation. Q->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16959974;Dbxref=PMID:16959974 Q9UKZ4 UniProtKB Natural variant 2396 2396 . . . ID=VAR_036600;Note=In a colorectal cancer sample%3B somatic mutation. L->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16959974;Dbxref=PMID:16959974 Q9UKZ4 UniProtKB Sequence conflict 261 261 . . . Note=F->S;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 1135 1135 . . . Note=G->D;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 1628 1628 . . . Note=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 1908 1908 . . . Note=P->S;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 2133 2137 . . . Note=MVICD->HGNMC;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 2179 2179 . . . Note=N->D;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 2271 2275 . . . Note=YADLT->VDATA;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 2388 2389 . . . Note=PN->AY;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q9UKZ4 UniProtKB Sequence conflict 2611 2611 . . . Note=V->L;Ontology_term=ECO:0000305;evidence=ECO:0000305