##gff-version 3
Q9UKB3	UniProtKB	Chain	1	198	.	.	.	ID=PRO_0000071066;Note=DnaJ homolog subfamily C member 12	
Q9UKB3	UniProtKB	Domain	14	79	.	.	.	Note=J;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00286	
Q9UKB3	UniProtKB	Region	114	169	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UKB3	UniProtKB	Compositional bias	114	156	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UKB3	UniProtKB	Modified residue	1	1	.	.	.	Note=N-acetylmethionine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22814378;Dbxref=PMID:22814378	
Q9UKB3	UniProtKB	Modified residue	160	160	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q9UKB3	UniProtKB	Modified residue	166	166	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R022	
Q9UKB3	UniProtKB	Modified residue	182	182	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R022	
Q9UKB3	UniProtKB	Alternative sequence	100	107	.	.	.	ID=VSP_001295;Note=In isoform B. SMHWVVRG->VGFSLGAT;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10760603;Dbxref=PMID:10760603	
Q9UKB3	UniProtKB	Alternative sequence	108	198	.	.	.	ID=VSP_001296;Note=In isoform B. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10760603;Dbxref=PMID:10760603	
Q9UKB3	UniProtKB	Natural variant	62	62	.	.	.	ID=VAR_090211;Note=In HPANBH4%3B likely pathogenic. A->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:39584997;Dbxref=PMID:39584997	
Q9UKB3	UniProtKB	Natural variant	72	198	.	.	.	ID=VAR_090212;Note=In HPANBH4%3B likely pathogenic. Missing;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:28794131,ECO:0000269|PubMed:39584997;Dbxref=PMID:28794131,PMID:39584997	
Q9UKB3	UniProtKB	Natural variant	72	72	.	.	.	ID=VAR_078797;Note=In HPANBH4%3B uncertain significance%3B decreased protein levels in homozygous patient cells%3B probably affects PAH stability%3B PAH activity is reduced in homozygous patient cells. R->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28132689;Dbxref=dbSNP:rs1035794099,PMID:28132689	
Q9UKB3	UniProtKB	Natural variant	79	198	.	.	.	ID=VAR_090213;Note=In HPANBH4%3B likely pathogenic. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:38248634;Dbxref=PMID:38248634	
Q9UKB3	UniProtKB	Natural variant	102	102	.	.	.	ID=VAR_090214;Note=In HPANBH4%3B uncertain significance. H->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32519510;Dbxref=dbSNP:rs1373961824,PMID:32519510	
Q9UKB3	UniProtKB	Natural variant	103	103	.	.	.	ID=VAR_090215;Note=In HPANBH4%3B likely pathogenic. W->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32333439;Dbxref=dbSNP:rs1841794635,PMID:32333439	
Q9UKB3	UniProtKB	Natural variant	124	124	.	.	.	ID=VAR_048913;Note=M->I;Dbxref=dbSNP:rs35690028	
Q9UKB3	UniProtKB	Natural variant	129	129	.	.	.	ID=VAR_048914;Note=C->W;Dbxref=dbSNP:rs36099123	
Q9UKB3	UniProtKB	Natural variant	175	198	.	.	.	ID=VAR_090216;Note=In HPANBH4%3B likely pathogenic%3B decreased mRNA and protein levels in homozygous patient cells%3B probably affects PAH stability%3B PAH levels and activity are severely reduced in homozygous patient cells. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32333439;Dbxref=PMID:32333439	
Q9UKB3	UniProtKB	Helix	15	18	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2CTQ	
Q9UKB3	UniProtKB	Helix	27	39	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2CTQ	
Q9UKB3	UniProtKB	Turn	43	45	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2CTQ	
Q9UKB3	UniProtKB	Helix	52	67	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2CTQ	
Q9UKB3	UniProtKB	Helix	69	81	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2CTQ	
Q9UKB3	UniProtKB	Helix	87	95	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2CTQ