##gff-version 3
Q9UK59	UniProtKB	Chain	1	544	.	.	.	ID=PRO_0000250358;Note=Lariat debranching enzyme	
Q9UK59	UniProtKB	Region	124	154	.	.	.	Note=Lariat recognition loop;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Region	395	463	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UK59	UniProtKB	Region	476	544	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UK59	UniProtKB	Compositional bias	395	412	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UK59	UniProtKB	Compositional bias	413	425	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UK59	UniProtKB	Compositional bias	429	439	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UK59	UniProtKB	Compositional bias	445	463	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UK59	UniProtKB	Compositional bias	512	522	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9UK59	UniProtKB	Binding site	8	8	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Binding site	10	10	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Binding site	39	39	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Binding site	84	84	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Binding site	174	174	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Binding site	226	226	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Binding site	228	228	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:C4M1P9	
Q9UK59	UniProtKB	Modified residue	128	128	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:19608861;Dbxref=PMID:19608861	
Q9UK59	UniProtKB	Modified residue	464	464	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:24275569;Dbxref=PMID:24275569	
Q9UK59	UniProtKB	Modified residue	474	474	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18669648;Dbxref=PMID:18669648	
Q9UK59	UniProtKB	Modified residue	478	478	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18669648;Dbxref=PMID:18669648	
Q9UK59	UniProtKB	Modified residue	479	479	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18669648;Dbxref=PMID:18669648	
Q9UK59	UniProtKB	Modified residue	485	485	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q923B1	
Q9UK59	UniProtKB	Modified residue	499	499	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q923B1	
Q9UK59	UniProtKB	Modified residue	514	514	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744,ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:17081983,ECO:0007744|PubMed:20068231,ECO:0007744|PubMed:21406692,ECO:0007744|PubMed:23186163;Dbxref=PMID:17081983,PMID:20068231,PMID:21406692,PMID:23186163	
Q9UK59	UniProtKB	Alternative sequence	1	232	.	.	.	ID=VSP_020631;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q9UK59	UniProtKB	Alternative sequence	233	237	.	.	.	ID=VSP_020632;Note=In isoform 2. ALMQH->MIHIV;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q9UK59	UniProtKB	Natural variant	13	13	.	.	.	ID=VAR_086073;Note=In IIAE11%3B decreased protein abundance%3B decreased RNA lariat debranching enzyme activity%3B requires 2 nucleotide substitutions. L->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29474921;Dbxref=dbSNP:rs2107907650,PMID:29474921	
Q9UK59	UniProtKB	Natural variant	17	17	.	.	.	ID=VAR_086074;Note=In IIAE11%3B decreased protein abundance%3B decreased RNA lariat debranching enzyme activity. Y->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29474921;Dbxref=dbSNP:rs2107907632,PMID:29474921	
Q9UK59	UniProtKB	Natural variant	67	67	.	.	.	ID=VAR_088992;Note=In XGIP%3B likely pathogenic%3B results in decreased function in lariat intron processing and lariant accumulation in homozygous patient cells%3B severely reduced protein abundance in homozygous patient cells. Y->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:37656279;Dbxref=PMID:37656279	
Q9UK59	UniProtKB	Natural variant	120	120	.	.	.	ID=VAR_086075;Note=In IIAE11%3B decreased protein abundance%3B decreased RNA lariat debranching enzyme activity. I->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29474921;Dbxref=dbSNP:rs2107906060,PMID:29474921	
Q9UK59	UniProtKB	Natural variant	197	544	.	.	.	ID=VAR_086076;Note=In IIAE11%3B loss of protein expression. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29474921;Dbxref=PMID:29474921	
Q9UK59	UniProtKB	Mutagenesis	85	85	.	.	.	Note=No effect on protein abundance. Loss of RNA lariat debranching enzyme activity. H->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29474921;Dbxref=PMID:29474921	
Q9UK59	UniProtKB	Sequence conflict	308	308	.	.	.	Note=N->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9UK59	UniProtKB	Sequence conflict	496	496	.	.	.	Note=T->L;Ontology_term=ECO:0000305;evidence=ECO:0000305