ID   Q9SS65_ARATH            Unreviewed;       499 AA.
AC   Q9SS65;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   02-SEP-2026, entry version 152.
DE   SubName: Full=Exostosin family protein {ECO:0000313|EMBL:AEE73967.1};
GN   Name=EDA5 {ECO:0000313|EMBL:AEE73967.1, ECO:0000313|TAIR:AT3G03650};
GN   OrderedLocusNames=At3g03650 {ECO:0000313|EMBL:AEE73967.1};
GN   ORFNames=T12J13.7 {ECO:0000313|EMBL:AEE73967.1}, T12J13_7
GN   {ECO:0000313|EMBL:AEE73967.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000313|EMBL:AEE73967.1, ECO:0000313|Proteomes:UP000006548};
RN   [1] {ECO:0000313|EMBL:AEE73967.1, ECO:0000313|Proteomes:UP000006548}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX   PubMed=11130713; DOI=10.1038/35048706;
RG   European Union Chromosome 3 Arabidopsis Sequencing Consortium;
RG   Institute for Genomic Research;
RG   Kazusa DNA Research Institute;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Blocker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M.,
RA   Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N.,
RA   Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L.,
RA   Weissenbach J., Saurin W., Quetier F., Schafer M., Muller-Auer S.,
RA   Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N.,
RA   Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P.,
RA   Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S.,
RA   Simionati B., Conrad A., Hornischer K., Kauer G., Lohnert T.H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schon O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwalder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.W., Mayer K.F., Kaul S.,
RA   Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2] {ECO:0000313|Proteomes:UP000006548}
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004323}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC       {ECO:0000256|ARBA:ARBA00010271}.
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DR   EMBL; CP002686; AEE73967.1; -; Genomic_DNA.
DR   RefSeq; NP_187015.1; NM_111236.3.
DR   AlphaFoldDB; Q9SS65; -.
DR   SMR; Q9SS65; -.
DR   IntAct; Q9SS65; 1.
DR   STRING; 3702.Q9SS65; -.
DR   PaxDb; 3702-Q9SS65; -.
DR   ProteomicsDB; 189304; -.
DR   GeneID; 821197; -.
DR   KEGG; ath:AT3G03650; -.
DR   TAIR; AT3G03650; EDA5.
DR   eggNOG; KOG1021; Eukaryota.
DR   HOGENOM; CLU_033763_1_0_1; -.
DR   OMA; HRMFITR; -.
DR   OrthoDB; 1924787at2759; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; IEA:InterPro.
DR   InterPro; IPR004263; Exostosin.
DR   InterPro; IPR040911; Exostosin_GT47.
DR   PANTHER; PTHR11062:SF216; EXOSTOSIN GT47 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11062; EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED; 1.
DR   Pfam; PF03016; Exostosin_GT47; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0007829|PeptideAtlas:Q9SS65,
KW   ECO:0007829|ProteomicsDB:Q9SS65};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          119..429
FT                   /note="Exostosin GT47"
FT                   /evidence="ECO:0000259|Pfam:PF03016"
FT   REGION          62..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..94
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..105
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   499 AA;  57145 MW;  17D89BB96894B096 CRC64;
     MGEKTNSRYL GVIITRKSII FLFISIITVL SWFFIFSSTN PNRVLDHISV SESTDVPLII
     IKNSNSSPQN NAPKPQNREG AETEEPIKEN RGGTKTESSM NQNRGETLRC IQRVSPSPRP
     LKVYMYDMSP EFHFGLLGWK PERNGVVWPD IRVNVPHHPG GLNLQHSVEY WLTLDLLFSE
     LPEDSRSSRA AIRVKNSSEA DVVFVPFFSS LSYNRFSKVN QKQKKSQDKE LQENVVKYVT
     SQKEWKTSGG KDHVIMAHHP NSMSTARHKL FPAMFVVADF GRYSPHVANV DKDIVAPYKH
     LVPSYVNDTS GFDGRPILLY FQGAIYRKAG GFVRQELYNL LKEEKDVHFS FGSVRNHGIS
     KAGEGMRSSK FCLNIAGDTP SSNRLFDAIA SHCIPVIISD DIELPYEDVL NYNEFCLFVR
     SSDALKKGFL MGLVRSIGRE EYNKMWLRLK EVERYFDLRF PVKDDEGDYA VQMIWKAVAR
     KAPLVKMKVH RFQRFTRPF
//