##gff-version 3 Q9NYQ7 UniProtKB Signal peptide 1 32 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Chain 33 3312 . . . ID=PRO_0000012918;Note=Cadherin EGF LAG seven-pass G-type receptor 3 Q9NYQ7 UniProtKB Topological domain 33 2540 . . . Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Transmembrane 2541 2561 . . . Note=Helical%3B Name%3D1;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Topological domain 2562 2572 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Transmembrane 2573 2593 . . . Note=Helical%3B Name%3D2;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Topological domain 2594 2601 . . . Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Transmembrane 2602 2622 . . . Note=Helical%3B Name%3D3;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Topological domain 2623 2643 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Transmembrane 2644 2664 . . . Note=Helical%3B Name%3D4;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Topological domain 2665 2681 . . . Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Transmembrane 2682 2702 . . . Note=Helical%3B Name%3D5;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Topological domain 2703 2725 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Transmembrane 2726 2746 . . . Note=Helical%3B Name%3D6;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Topological domain 2747 2753 . . . Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Transmembrane 2754 2774 . . . Note=Helical%3B Name%3D7;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Topological domain 2775 3312 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Domain 326 433 . . . Note=Cadherin 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 434 545 . . . Note=Cadherin 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 546 651 . . . Note=Cadherin 3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 652 756 . . . Note=Cadherin 4;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 757 858 . . . Note=Cadherin 5;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 859 961 . . . Note=Cadherin 6;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 962 1067 . . . Note=Cadherin 7;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 1068 1169 . . . Note=Cadherin 8;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 1170 1265 . . . Note=Cadherin 9;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00043 Q9NYQ7 UniProtKB Domain 1375 1433 . . . Note=EGF-like 1%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 1435 1471 . . . Note=EGF-like 2%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 1475 1514 . . . Note=EGF-like 3%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 1515 1719 . . . Note=Laminin G-like 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00122 Q9NYQ7 UniProtKB Domain 1722 1758 . . . Note=EGF-like 4%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 1764 1944 . . . Note=Laminin G-like 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00122 Q9NYQ7 UniProtKB Domain 1946 1982 . . . Note=EGF-like 5%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 1983 2020 . . . Note=EGF-like 6%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 2021 2053 . . . Note=EGF-like 7%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 2055 2090 . . . Note=EGF-like 8%3B calcium-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00076 Q9NYQ7 UniProtKB Domain 2077 2124 . . . Note=Laminin EGF-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00460 Q9NYQ7 UniProtKB Domain 2368 2530 . . . Note=GAIN-B;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00098 Q9NYQ7 UniProtKB Region 90 112 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Region 143 199 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Region 212 306 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Region 2361 2399 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Region 2480 2530 . . . Note=GPS;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00098 Q9NYQ7 UniProtKB Region 2888 2927 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Region 2978 3006 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Region 3086 3243 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Region 3256 3312 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 159 173 . . . Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 290 299 . . . Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 2380 2391 . . . Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 2890 2900 . . . Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 3175 3198 . . . Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 3256 3265 . . . Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 3272 3281 . . . Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Compositional bias 3287 3300 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q9NYQ7 UniProtKB Modified residue 1963 1963 . . . Note=(3R)-3-hydroxyaspartate;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Modified residue 2126 2126 . . . Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O88278 Q9NYQ7 UniProtKB Modified residue 3051 3051 . . . Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O88278 Q9NYQ7 UniProtKB Modified residue 3097 3097 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O88278 Q9NYQ7 UniProtKB Glycosylation 632 632 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 847 847 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 1182 1182 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 1222 1222 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 1317 1317 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 1327 1327 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 1649 1649 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 1713 1713 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 1770 1770 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 2053 2053 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 2177 2177 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 2196 2196 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 2386 2386 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 2474 2474 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Glycosylation 2506 2506 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q9NYQ7 UniProtKB Disulfide bond 1379 1390 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1384 1421 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1423 1432 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1439 1450 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1444 1459 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1461 1470 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1479 1490 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1484 1500 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1502 1513 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1693 1719 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1726 1737 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1731 1746 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1748 1757 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1915 1944 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1950 1961 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1955 1970 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1972 1981 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1985 1996 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 1990 2008 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2010 2019 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2027 2040 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2042 2052 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2059 2074 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2061 2077 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2079 2089 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2098 2107 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2110 2122 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 Q9NYQ7 UniProtKB Disulfide bond 2480 2512 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00098 Q9NYQ7 UniProtKB Disulfide bond 2500 2514 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00098 Q9NYQ7 UniProtKB Alternative sequence 2158 2158 . . . ID=VSP_037125;Note=In isoform 2. G->GLRGAG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9693030;Dbxref=PMID:9693030 Q9NYQ7 UniProtKB Natural variant 157 157 . . . ID=VAR_020022;Note=A->P;Dbxref=dbSNP:rs3733085 Q9NYQ7 UniProtKB Natural variant 805 805 . . . ID=VAR_020023;Note=S->T;Dbxref=dbSNP:rs3821875 Q9NYQ7 UniProtKB Natural variant 1758 1758 . . . ID=VAR_055101;Note=Q->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30410802;Dbxref=dbSNP:rs12107252,PMID:30410802 Q9NYQ7 UniProtKB Natural variant 2136 2136 . . . ID=VAR_083108;Note=Found in a patient with epileptic encephalopathy%3B uncertain significance. G->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:24358150;Dbxref=dbSNP:rs587777163,PMID:24358150 Q9NYQ7 UniProtKB Natural variant 2630 2630 . . . ID=VAR_083109;Note=M->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23339110;Dbxref=dbSNP:rs149614835,PMID:23339110 Q9NYQ7 UniProtKB Sequence conflict 13 13 . . . Note=G->E;Ontology_term=ECO:0000305;evidence=ECO:0000305