ID   Q9CI24_LACLA            Unreviewed;       210 AA.
AC   Q9CI24;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   02-SEP-2026, entry version 107.
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN   Name=yfcI {ECO:0000313|EMBL:AAK04640.1};
GN   ORFNames=L128550 {ECO:0000313|EMBL:AAK04640.1};
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623 {ECO:0000313|EMBL:AAK04640.1, ECO:0000313|Proteomes:UP000002196};
RN   [1] {ECO:0000313|EMBL:AAK04640.1, ECO:0000313|Proteomes:UP000002196}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403 {ECO:0000313|EMBL:AAK04640.1,
RC   ECO:0000313|Proteomes:UP000002196};
RX   PubMed=11337471; DOI=10.1101/gr.GR-1697R;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR   EMBL; AE005176; AAK04640.1; -; Genomic_DNA.
DR   PIR; F86692; F86692.
DR   RefSeq; WP_003131748.1; NC_002662.1.
DR   AlphaFoldDB; Q9CI24; -.
DR   EnsemblBacteria; AAK04640; AAK04640; L128550.
DR   KEGG; lla:L128550; -.
DR   PATRIC; fig|272623.7.peg.580; -.
DR   eggNOG; COG0491; Bacteria.
DR   HOGENOM; CLU_030571_5_2_9; -.
DR   OrthoDB; 9802248at2; -.
DR   Proteomes; UP000002196; Chromosome.
DR   CDD; cd06262; metallo-hydrolase-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR051453; MBL_Glyoxalase_II.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR46233; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR   PANTHER; PTHR46233:SF3; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002196};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          12..193
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
FT   REGION          189..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        198..210
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   210 AA;  23732 MW;  D2348872511D0EF1 CRC64;
     MKIEKIVNKI AQENTYLLSN STSHLIIDPG SDSSALLERL KITDKTISAI LLTHAHFDHI
     IGLNELRKHF PDVPIYLHSA EKEWMKNPKL NASFFFLGTA VTGPEADYFY EINQFYDIDA
     FKFQVLETPG HSIGGVSLLF KLENESFVFS GDALFKNAIG RWDLPTGNQA QLLKSIREQL
     FTLDENTQVF PGHGPKTSIG TEKQNNPFFQ
//