ID   Q9AAM3_CAUVC            Unreviewed;       867 AA.
AC   Q9AAM3;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   04-NOV-2026, entry version 114.
DE   RecName: Full=Alpha-mannosidase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=CC_0574 {ECO:0000313|EMBL:AAK22560.1};
OS   Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15)
OS   (Caulobacter crescentus).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Caulobacterales; Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650 {ECO:0000313|EMBL:AAK22560.1, ECO:0000313|Proteomes:UP000001816};
RN   [1] {ECO:0000313|EMBL:AAK22560.1, ECO:0000313|Proteomes:UP000001816}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15 {ECO:0000313|Proteomes:UP000001816};
RX   PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R., Ohta N., Maddock J.R., Potocka I.,
RA   Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T.,
RA   Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J.,
RA   Craven M.B., Khouri H., Shetty J., Berry K., Utterback T., Tran K.,
RA   Wolf A., Vamathevan J., Ermolaeva M., White O., Salzberg S.L., Venter J.C.,
RA   Shapiro L., Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
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DR   EMBL; AE005673; AAK22560.1; -; Genomic_DNA.
DR   PIR; D87320; D87320.
DR   RefSeq; WP_010918461.1; NC_002696.2.
DR   AlphaFoldDB; Q9AAM3; -.
DR   SMR; Q9AAM3; -.
DR   STRING; 190650.CC_0574; -.
DR   EnsemblBacteria; AAK22560; AAK22560; CC_0574.
DR   KEGG; ccr:CC_0574; -.
DR   PATRIC; fig|190650.5.peg.586; -.
DR   eggNOG; COG3537; Bacteria.
DR   HOGENOM; CLU_003690_2_0_5; -.
DR   OMA; AAKWQVF; -.
DR   BioCyc; CAULO:CC0574-MONOMER; -.
DR   Proteomes; UP000001816; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0000224; F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity; IEA:TreeGrafter.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006516; P:glycoprotein catabolic process; IEA:TreeGrafter.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR   Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR005887; GH92_a_mannosidase_put.
DR   InterPro; IPR041371; GH92_N.
DR   InterPro; IPR012939; Glyco_hydro_92.
DR   InterPro; IPR050883; PNGase.
DR   NCBIfam; TIGR01180; aman2_put; 1.
DR   PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR   PANTHER; PTHR12143:SF43; PUTATIVE-RELATED; 1.
DR   Pfam; PF07971; Glyco_hydro_92; 1.
DR   Pfam; PF17678; Glyco_hydro_92N; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001816};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..867
FT                   /note="Alpha-mannosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004323489"
FT   DOMAIN          49..273
FT                   /note="Glycosyl hydrolase family 92 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17678"
FT   DOMAIN          280..728
FT                   /note="Glycosyl hydrolase family 92"
FT                   /evidence="ECO:0000259|Pfam:PF07971"
FT   REGION          49..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   867 AA;  94462 MW;  BFAE079A8F3E5A9B CRC64;
     MNPGKGPVLR FRVQLLVVGF ALALGAAHQA QAAPGRALYK LPDLRVGLGD DNQGDTIPGP
     TRPNGSIHPS PDTLKASNAG YNPAEPISGF AQLHSQGSGG VTTYGTFLLS PQVGEPVFDE
     AAHLSPKADE TLAADAYSVR LTRYDTKVEI TSAHYAAIYR LTYPTTDQAQ VVLDVTRKVG
     GLVASEQADV QLFPEQGRIV GHVKAKGYWN PALIDIWFVA EFDQNPTAWG VFDKAERRDG
     ALSGRTGSDE RLGAWLTFKT TPTKPLLVKI AVSFVSAEMA KALLDREIPD WDFERVRRDT
     QAAWNDRLGQ VRVEGMTESQ QRRFYSALYH ASTHPRDRSL DQPAARLGRP NWDEHYTLWD
     TYRTLFPLIS VLRPSLYTAN VNSLIHTFDK FGAADTAIIG GQNYHVGQGG DEVDNVLGEA
     LLRGAEGVNW RDAWRVARFN AFERRRPRYL ESGYFAVGDR SPEPNNQRAK SGSSTLGFAL
     NDFYAAQVAA KAGQTDEAKI LTERSANWRK IWNPDATSDG FSGFLMPRYA DGKFQDIDPK
     LGWDGKVHNN VGYYEGTAWI YSYGVLHDLP GLVEAMGGRV RFNERLNHAL DAGLIDITNE
     PSFATPWLFH AIGRADLSSR WAGEVVKHFT ADAYPGDEDA GAMSSNFVFN SLGLFPKLGS
     DLYYLHGPRH GRTVIQLENG KTLEILAAKA GASRPYIASA SFNGKPLAGP YVSQAQLLGG
     GVLSLSMSDQ PGQWIYEGAV LTVRADQPSL VDGKTSTGWR AASGQSVTFS LKAPACIAAY
     SVSVGPDQAD PSHWTLQAYD GRAWVSVDQQ SNVVFDHRHA TRTFPLAPGR YARLRWVLDG
     GSEASVSEVE LIAGASCAAP TSGAPLL
//