ID VOPP1_HUMAN Reviewed; 172 AA. AC Q96AW1; B0AZU1; B2RAT4; B3KS72; C9JWR3; Q6FIE3; Q8NBN8; Q96RE5; Q9H0W4; DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot. DT 01-DEC-2001, sequence version 1. DT 02-SEP-2026, entry version 163. DE RecName: Full=WW domain binding protein VOPP1 {ECO:0000312|HGNC:HGNC:34518}; DE AltName: Full=EGFR-coamplified and overexpressed protein {ECO:0000303|PubMed:20571887}; DE Short=ECop {ECO:0000303|PubMed:20571887}; DE AltName: Full=Glioblastoma-amplified secreted protein; DE AltName: Full=Putative NF-kappa-B-activating protein 055N; DE AltName: Full=Vesicular, overexpressed in cancer, prosurvival protein 1; DE Flags: Precursor; GN Name=VOPP1 {ECO:0000312|HGNC:HGNC:34518}; Synonyms=ECOP, GASP; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). RC TISSUE=Brain; RX PubMed=11230166; DOI=10.1101/gr.gr1547r; RA Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., RA Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., RA Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., RA Ottenwaelder B., Obermaier B., Tampe J., Heubner D., Wambutt R., Korn B., RA Klein M., Poustka A.; RT "Towards a catalog of human genes and proteins: sequencing and analysis of RT 500 novel complete protein coding human cDNAs."; RL Genome Res. 11:422-435(2001). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). RC TISSUE=Lung fibroblast; RX PubMed=12761501; DOI=10.1038/sj.onc.1206406; RA Matsuda A., Suzuki Y., Honda G., Muramatsu S., Matsuzaki O., Nagano Y., RA Doi T., Shimotohno K., Harada T., Nishida E., Hayashi H., Sugano S.; RT "Large-scale identification and characterization of human genes that RT activate NF-kappaB and MAPK signaling pathways."; RL Oncogene 22:3307-3318(2003). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3). RC TISSUE=Spleen, Synovial cell, and Umbilical cord blood; RX PubMed=14702039; DOI=10.1038/ng1285; RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., RA Isogai T., Sugano S.; RT "Complete sequencing and characterization of 21,243 full-length human RT cDNAs."; RL Nat. Genet. 36:40-45(2004). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). RA Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.; RT "Cloning of human full open reading frames in Gateway(TM) system entry RT vector (pDONR201)."; RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12853948; DOI=10.1038/nature01782; RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H., RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., RA Wilson R.K.; RT "The DNA sequence of human chromosome 7."; RL Nature 424:157-164(2003). RN [6] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12690205; DOI=10.1126/science.1083423; RA Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., RA Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., RA Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., RA Kanematsu E., Gentles S., Christopoulos C.C., Choufani S., Kwasnicka D., RA Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., RA Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., RA Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., RA Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., RA Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., RA Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., RA Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., RA Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., RA Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., RA Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., RA Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., RA Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., RA Adams M.D., Tsui L.-C.; RT "Human chromosome 7: DNA sequence and biology."; RL Science 300:767-772(2003). RN [7] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., RA Hunkapiller M.W., Myers E.W., Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [8] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). RC TISSUE=Lymph; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA project: RT the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [9] RP NUCLEOTIDE SEQUENCE [MRNA] OF 14-172 (ISOFORM 1), AND TISSUE SPECIFICITY. RX PubMed=11916499; DOI=10.1093/neuonc/4.2.86; RA Eley G.D., Reiter J.L., Pandita A., Park S., Jenkins R.B., Maihle N.J., RA James C.D.; RT "A chromosomal region 7p11.2 transcript map: its development and RT application to the study of EGFR amplicons in glioblastoma."; RL Neuro-oncol. 4:86-94(2002). RN [10] RP FUNCTION. RX PubMed=15735698; DOI=10.1038/sj.onc.1208496; RA Park S., James C.D.; RT "ECop (EGFR-coamplified and overexpressed protein), a novel protein, RT regulates NF-kappaB transcriptional activity and associated apoptotic RT response in an IkappaBalpha-dependent manner."; RL Oncogene 24:2495-2502(2005). RN [11] RP SUBCELLULAR LOCATION. RX PubMed=20571887; DOI=10.1007/s10735-010-9272-8; RA Baras A., Moskaluk C.A.; RT "Intracellular localization of GASP/ECOP/VOPP1."; RL J. Mol. Histol. 41:153-164(2010). RN [12] RP FUNCTION, INTERACTION WITH WWOX, SUBCELLULAR LOCATION, AND MUTAGENESIS OF RP TYR-119; TYR-157 AND TYR-165. RX PubMed=30285739; DOI=10.1186/s12915-018-0576-6; RA Bonin F., Taouis K., Azorin P., Petitalot A., Tariq Z., Nola S., RA Bouteille N., Tury S., Vacher S., Bieche I., Rais K.A., Pierron G., RA Fuhrmann L., Vincent-Salomon A., Formstecher E., Camonis J., Lidereau R., RA Lallemand F., Driouch K.; RT "VOPP1 promotes breast tumorigenesis by interacting with the tumor RT suppressor WWOX."; RL BMC Biol. 16:109-109(2018). CC -!- FUNCTION: Increases the transcriptional activity of NFKB1 by CC facilitating its nuclear translocation, DNA-binding and associated CC apoptotic response, when overexpressed (PubMed:15735698). May sequester CC WWOX in lysosomal vesicles and thereby regulate WWOX role as tumor CC suppressor (PubMed:30285739). {ECO:0000269|PubMed:15735698, CC ECO:0000269|PubMed:30285739}. CC -!- SUBUNIT: Interacts with WWOX (via WW domain). CC {ECO:0000269|PubMed:30285739}. CC -!- INTERACTION: CC Q96AW1; Q9NZC7: WWOX; NbExp=7; IntAct=EBI-715058, EBI-4320739; CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane CC {ECO:0000269|PubMed:20571887}; Single-pass type I membrane protein CC {ECO:0000269|PubMed:20571887}. Late endosome membrane CC {ECO:0000269|PubMed:30285739}; Single-pass membrane protein CC {ECO:0000269|PubMed:30285739}. Lysosome membrane CC {ECO:0000269|PubMed:30285739}; Single-pass membrane protein CC {ECO:0000269|PubMed:30285739}. Note=When overexpressed, localizes in CC the nucleus and perinuclear regions. {ECO:0000269|PubMed:15735698}. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative splicing; Named isoforms=4; CC Name=1; CC IsoId=Q96AW1-1; Sequence=Displayed; CC Name=2; CC IsoId=Q96AW1-2; Sequence=VSP_043868; CC Name=3; CC IsoId=Q96AW1-3; Sequence=VSP_043867; CC Name=4; CC IsoId=Q96AW1-4; Sequence=VSP_055723; CC -!- TISSUE SPECIFICITY: Widely expressed with highest levels in thymus and CC ovary. {ECO:0000269|PubMed:11916499}. CC -!- SIMILARITY: Belongs to the VOPP1/ECOP family. {ECO:0000305}. CC -!- SEQUENCE CAUTION: CC Sequence=AAK82888.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL136610; CAB66545.1; -; mRNA. DR EMBL; AB097004; BAC77357.1; -; mRNA. DR EMBL; AK075391; BAC11590.1; -; mRNA. DR EMBL; AK092992; BAG52634.1; -; mRNA. DR EMBL; AK314338; BAG36981.1; -; mRNA. DR EMBL; AK315882; BAF98773.1; -; mRNA. DR EMBL; CR533483; CAG38514.1; -; mRNA. DR EMBL; AC073237; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC073347; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AC099681; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CH236957; EAL23811.1; -; Genomic_DNA. DR EMBL; CH471201; EAW50969.1; -; Genomic_DNA. DR EMBL; BC016650; AAH16650.1; -; mRNA. DR EMBL; AF395824; AAK82888.1; ALT_SEQ; mRNA. DR CCDS; CCDS47588.1; -. [Q96AW1-1] DR CCDS; CCDS64654.1; -. [Q96AW1-2] DR CCDS; CCDS64655.1; -. [Q96AW1-3] DR CCDS; CCDS64656.1; -. [Q96AW1-4] DR RefSeq; NP_001271211.1; NM_001284282.2. [Q96AW1-4] DR RefSeq; NP_001271212.1; NM_001284283.2. [Q96AW1-3] DR RefSeq; NP_001271213.1; NM_001284284.1. [Q96AW1-2] DR RefSeq; NP_001308178.1; NM_001321249.2. DR RefSeq; NP_001308179.1; NM_001321250.2. DR RefSeq; NP_001308180.1; NM_001321251.1. DR RefSeq; NP_110423.3; NM_030796.5. [Q96AW1-1] DR AlphaFoldDB; Q96AW1; -. DR BioGRID; 123516; 13. DR FunCoup; Q96AW1; 154. DR IntAct; Q96AW1; 24. DR STRING; 9606.ENSP00000285279; -. DR iPTMnet; Q96AW1; -. DR PhosphoSitePlus; Q96AW1; -. DR SwissPalm; Q96AW1; -. DR BioMuta; VOPP1; -. DR DMDM; 74760714; -. DR jPOST; Q96AW1; -. DR MassIVE; Q96AW1; -. DR PaxDb; 9606-ENSP00000285279; -. DR PeptideAtlas; Q96AW1; -. DR ProteomicsDB; 12027; -. DR ProteomicsDB; 76001; -. [Q96AW1-1] DR ProteomicsDB; 76002; -. [Q96AW1-2] DR ProteomicsDB; 76003; -. [Q96AW1-3] DR Antibodypedia; 27923; 118 antibodies from 20 providers. DR DNASU; 81552; -. DR Ensembl; ENST00000285279.10; ENSP00000285279.5; ENSG00000154978.14. [Q96AW1-1] DR Ensembl; ENST00000418904.5; ENSP00000393210.1; ENSG00000154978.14. [Q96AW1-4] DR Ensembl; ENST00000433959.5; ENSP00000415230.1; ENSG00000154978.14. [Q96AW1-2] DR Ensembl; ENST00000625836.2; ENSP00000486983.1; ENSG00000154978.14. [Q96AW1-3] DR GeneID; 81552; -. DR KEGG; hsa:81552; -. DR MANE-Select; ENST00000285279.10; ENSP00000285279.5; NM_030796.5; NP_110423.3. DR UCSC; uc003tqq.5; human. [Q96AW1-1] DR AGR; HGNC:34518; -. DR ClinPGx; PA165618503; -. DR CTD; 81552; -. DR DisGeNET; 81552; -. DR GeneCards; VOPP1; -. DR HGNC; HGNC:34518; VOPP1. DR HPA; ENSG00000154978; Tissue enhanced (retina). DR MIM; 611915; gene. DR OpenTargets; ENSG00000154978; -. DR VEuPathDB; HostDB:ENSG00000154978; -. DR eggNOG; ENOG502RYIF; Eukaryota. DR GeneTree; ENSGT00390000015821; -. DR HOGENOM; CLU_1694909_0_0_1; -. DR InParanoid; Q96AW1; -. DR OMA; FLECIEA; -. DR OrthoDB; 6629737at2759; -. DR PAN-GO; Q96AW1; 1 GO annotation based on evolutionary models. DR PhylomeDB; Q96AW1; -. DR PathwayCommons; Q96AW1; -. DR SignaLink; Q96AW1; -. DR Agora; ENSG00000154978; -. DR BioGRID-ORCS; 81552; 68 hits in 1156 CRISPR screens. DR ChiTaRS; VOPP1; human. DR GeneWiki; ECOP; -. DR GenomeRNAi; 81552; -. DR Pharos; Q96AW1; Tbio. DR PRO; PR:Q96AW1; -. DR Proteomes; UP000005640; Chromosome 7. DR RNAct; Q96AW1; protein. DR Bgee; ENSG00000154978; Expressed in thymus and 211 other cell types or tissues. DR ExpressionAtlas; Q96AW1; baseline and differential. DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IDA:UniProtKB. DR GO; GO:0005768; C:endosome; IDA:LIFEdb. DR GO; GO:0005770; C:late endosome; IDA:UniProtKB. DR GO; GO:0031902; C:late endosome membrane; EXP:UniProtKB. DR GO; GO:0005765; C:lysosomal membrane; EXP:UniProtKB. DR GO; GO:0005764; C:lysosome; IDA:UniProtKB. DR GO; GO:0031090; C:organelle membrane; IDA:UniProtKB. DR GO; GO:0019899; F:enzyme binding; IPI:UniProtKB. DR GO; GO:0140311; F:protein sequestering activity; IDA:MGI. DR InterPro; IPR026229; VOPP1. DR InterPro; IPR060430; VOPP1_dom. DR InterPro; IPR060429; VOPP1_N. DR PANTHER; PTHR14971; VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1; 1. DR PANTHER; PTHR14971:SF2; VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1; 1. DR Pfam; PF27963; VOPP1_C; 1. DR Pfam; PF27964; VOPP1_N; 1. DR PRINTS; PR02068; VOPPROTEIN1. PE 1: Evidence at protein level; KW Alternative splicing; Cytoplasmic vesicle; Endosome; Lysosome; Membrane; KW Proteomics identification; Reference proteome; Signal; Transcription; KW Transcription regulation; Transmembrane; Transmembrane helix. FT SIGNAL 1..22 FT /evidence="ECO:0000255" FT CHAIN 23..172 FT /note="WW domain binding protein VOPP1" FT /id="PRO_0000325917" FT TOPO_DOM 23..60 FT /note="Extracellular" FT /evidence="ECO:0000255" FT TRANSMEM 61..81 FT /note="Helical" FT /evidence="ECO:0000255" FT TOPO_DOM 82..172 FT /note="Cytoplasmic" FT /evidence="ECO:0000255" FT REGION 102..153 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 104..119 FT /note="Pro residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT VAR_SEQ 1..18 FT /note="MRRQPAKVAALLLGLLLE -> M (in isoform 4)" FT /evidence="ECO:0000305" FT /id="VSP_055723" FT VAR_SEQ 2..18 FT /note="RRQPAKVAALLLGLLLE -> LSETLGYLSSVLLQ (in isoform 3)" FT /evidence="ECO:0000303|PubMed:14702039" FT /id="VSP_043867" FT VAR_SEQ 4..18 FT /note="QPAKVAALLLGLLLE -> TGSHAQ (in isoform 2)" FT /evidence="ECO:0000303|PubMed:14702039" FT /id="VSP_043868" FT MUTAGEN 119 FT /note="Y->A: Does not affect binding to WWOX." FT /evidence="ECO:0000269|PubMed:30285739" FT MUTAGEN 157 FT /note="Y->A: Does not affect binding to WWOX." FT /evidence="ECO:0000269|PubMed:30285739" FT MUTAGEN 165 FT /note="Y->A: Reduces binding to WWOX." FT /evidence="ECO:0000269|PubMed:30285739" FT CONFLICT 92 FT /note="E -> K (in Ref. 4; CAG38514)" FT /evidence="ECO:0000305" FT CONFLICT 111 FT /note="A -> T (in Ref. 3; BAC11590)" FT /evidence="ECO:0000305" FT CONFLICT 134 FT /note="M -> T (in Ref. 2; CAB66545 and 4; CAG38514)" FT /evidence="ECO:0000305" SQ SEQUENCE 172 AA; 19224 MW; 7F7F75231C2A4276 CRC64; MRRQPAKVAA LLLGLLLECT EAKKHCWYFE GLYPTYYICR SYEDCCGSRC CVRALSIQRL WYFWFLLMMG VLFCCGAGFF IRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK //