ID   Q93R48_THETH            Unreviewed;       666 AA.
AC   Q93R48;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-DEC-2001, sequence version 1.
DT   02-SEP-2026, entry version 73.
DE   RecName: Full=Single-stranded-DNA-specific exonuclease RecJ {ECO:0000256|ARBA:ARBA00019841};
GN   Name=recJ {ECO:0000313|EMBL:BAB61865.1};
OS   Thermus thermophilus.
OC   Bacteria; Thermotogati; Deinococcota; Deinococci; Thermales; Thermaceae;
OC   Thermus.
OX   NCBI_TaxID=274 {ECO:0000313|EMBL:BAB61865.1};
RN   [1] {ECO:0000313|EMBL:BAB61865.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HB8 {ECO:0000313|EMBL:BAB61865.1};
RX   PubMed=11713311; DOI=10.1093/nar/29.22.4617;
RA   Yamagata A., Masui R., Kakuta Y., Kuramitsu S., Fukuyama K.;
RT   "Overexpression, purification and characterization of RecJ protein from
RT   Thermus thermophilus HB8 and its core domain.";
RL   Nucleic Acids Res. 29:4617-4624(2001).
CC   -!- SIMILARITY: Belongs to the RecJ family.
CC       {ECO:0000256|ARBA:ARBA00005915}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB064549; BAB61865.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q93R48; -.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.10.310.30; -; 1.
DR   Gene3D; 3.40.50.12810; -; 1.
DR   Gene3D; 3.90.1640.30; -; 1.
DR   InterPro; IPR001667; DDH_dom.
DR   InterPro; IPR038763; DHH_sf.
DR   InterPro; IPR003156; DHHA1_dom.
DR   InterPro; IPR054598; RecJ_C_thermales.
DR   InterPro; IPR041122; RecJ_OB.
DR   InterPro; IPR051673; SSDNA_exonuclease_RecJ.
DR   PANTHER; PTHR30255; SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ; 1.
DR   PANTHER; PTHR30255:SF2; SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ; 1.
DR   Pfam; PF01368; DHH; 1.
DR   Pfam; PF02272; DHHA1; 1.
DR   Pfam; PF22047; RecJ_C; 1.
DR   Pfam; PF17768; RecJ_OB; 1.
DR   SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE   3: Inferred from homology;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:BAB61865.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722}.
FT   DOMAIN          74..218
FT                   /note="DDH"
FT                   /evidence="ECO:0000259|Pfam:PF01368"
FT   DOMAIN          331..418
FT                   /note="DHHA1"
FT                   /evidence="ECO:0000259|Pfam:PF02272"
FT   DOMAIN          441..524
FT                   /note="RecJ OB"
FT                   /evidence="ECO:0000259|Pfam:PF17768"
FT   DOMAIN          540..655
FT                   /note="Single-stranded-DNA-specific exonuclease RecJ C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF22047"
SQ   SEQUENCE   666 AA;  72853 MW;  051D5419E3FE0074 CRC64;
     MRDRVRWRVL SLPPLAQWRE VMAALEVGPE AALAYWHRGF RRKEDLDPPL ALLPLKGLRE
     AAALLEEALR QGKRIRVHGD YDADGLTGTA ILVRGLAALG ADVHPFIPHR LEEGYGVLME
     RVPEHLEASD LFLTVDCGIT NHAELRELLE NGVEVIVTDH HTPGKTPSPG LVVHPALTPD
     LKEKPTGAGV VFLLLWALHE RLGLPPPLEY ADLAAVGTIA DVAPLWGWNR ALVKEGLARI
     PASSWVGLRL LAEAVGYTGK AVEVAFRIAP RINAASRLGE AEKALRLLLT DDAAEAQALV
     GELHRLNARR QTLEEAMLRK LLPQADPEAK AIVLLDPEGH PGVMGIVASR ILEATLRPVF
     LVAQGKGTVR SLAPISAVEA LRSAEDLLLR YGGHKEAAGF AMDEALFPAF KARVEAYAAR
     FPDPVREVAL LDLLPEPGLL PQVFRELALL EPYGEGNPEP LFLLFGAPEE ARRLGEGRHL
     AFRLKGVRVL AWKQGDLALP PEVEVAGLLS ENAWNGHLAY EVQAVDLRKP EALEGGIAPF
     AYPLPLLEAL ARARLGEGVY VPEDNPEGLD YARKAGFRLL PPEEAGLWLG LPPRPVLGRR
     VEVALGREAR ARLSAPPVLH TPEARLKALV HRRLLFAYER RHPGLFSEAL LAYWEVNRVQ
     EPAGSP
//