ID   SURE2_PYRAE             Reviewed;         249 AA.
AC   Q8ZSY4;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   05-MAR-2002, sequence version 1.
DT   01-MAY-2007, entry version 33.
DE   5'-nucleotidase surE2 (EC 3.1.3.5) (Nucleoside 5'-monophosphate
DE   phosphohydrolase 2).
GN   Name=surE2; OrderedLocusNames=PAE3523;
OS   Pyrobaculum aerophilum.
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales;
OC   Thermoproteaceae; Pyrobaculum.
OX   NCBI_TaxID=13773;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827;
RX   MEDLINE=21664397; PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- FUNCTION: Nucleotidase that shows phosphatase activity on
CC       nucleoside 5'-monophosphates (By similarity).
CC   -!- CATALYTIC ACTIVITY: A 5'-ribonucleotide + H(2)O = a ribonucleoside
CC       + phosphate.
CC   -!- COFACTOR: Binds 1 divalent metal cation per subunit (By
CC       similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the surE nucleotidase family.
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DR   EMBL; AE009935; AAL64979.1; -; Genomic_DNA.
DR   HSSP; Q8ZU79; 1L5X.
DR   GenomeReviews; AE009441_GR; PAE3523.
DR   KEGG; pai:PAE3523; -.
DR   GO; GO:0008253; F:5'-nucleotidase activity; IEA:HAMAP.
DR   GO; GO:0046872; F:metal ion binding; IEA:HAMAP.
DR   HAMAP; MF_00060; -; 1.
DR   InterPro; IPR002828; SurE.
DR   Gene3D; G3DSA:3.40.1210.10; G3DSA:3.40.1210.10; 1.
DR   Pfam; PF01975; SurE; 1.
DR   ProDom; PD005378; SurE; 1.
DR   TIGRFAMs; TIGR00087; surE; 1.
KW   Complete proteome; Hydrolase; Metal-binding; Nucleotide-binding.
FT   CHAIN         1    249       5'-nucleotidase surE2.
FT                                /FTId=PRO_0000111870.
FT   METAL         8      8       Divalent metal cation (By similarity).
FT   METAL         9      9       Divalent metal cation (By similarity).
FT   METAL        40     40       Divalent metal cation (By similarity).
FT   METAL        90     90       Divalent metal cation (By similarity).
SQ   SEQUENCE   249 AA;  26661 MW;  79A57CA1EBF4A07B CRC64;
     MKIVVTNDDG PHSPLLEPLV RGLEAVGNEV VVVVPERPRS AAGLARTYHK PLRVRRLGGY
     YVVNGFPADA VFLALKLIAP DAELVISGVN VGENIGIEAT YGSGTVGAAL QAGVLGVPSI
     AASMEVGGDV DFMIKVVEGA VASARAGLDG VLAVSINIPS VWKGGVYCVR KLARAVYRER
     LYEGVDPRGE KYYWRWGPRR SEFEPDTDAY YFYYMRGVTV LGLSESGVAS VENFGRKLGQ
     LIGAVKVDC
//