ID   Q8TPN2_METAC            Unreviewed;       549 AA.
AC   Q8TPN2;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   02-SEP-2026, entry version 105.
DE   SubName: Full=Phosphorylase {ECO:0000313|EMBL:AAM05279.1};
GN   Name=malP {ECO:0000313|EMBL:AAM05279.1};
GN   OrderedLocusNames=MA_1874 {ECO:0000313|EMBL:AAM05279.1};
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC   Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM05279.1, ECO:0000313|Proteomes:UP000002487};
RN   [1] {ECO:0000313|EMBL:AAM05279.1, ECO:0000313|Proteomes:UP000002487}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC   {ECO:0000313|Proteomes:UP000002487};
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA   Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA   Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA   de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA   Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA   Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- SIMILARITY: Belongs to the glycogen phosphorylase family.
CC       {ECO:0000256|ARBA:ARBA00006047}.
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DR   EMBL; AE010299; AAM05279.1; -; Genomic_DNA.
DR   RefSeq; WP_011021875.1; NC_003552.1.
DR   AlphaFoldDB; Q8TPN2; -.
DR   FunCoup; Q8TPN2; 2.
DR   STRING; 188937.MA_1874; -.
DR   EnsemblBacteria; AAM05279; AAM05279; MA_1874.
DR   GeneID; 1473763; -.
DR   KEGG; mac:MA_1874; -.
DR   HOGENOM; CLU_015112_1_0_2; -.
DR   InParanoid; Q8TPN2; -.
DR   PhylomeDB; Q8TPN2; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0008184; F:glycogen phosphorylase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 3.
DR   InterPro; IPR011834; Agluc_phsphrylas.
DR   InterPro; IPR000811; Glyco_trans_35.
DR   NCBIfam; TIGR02094; more_P_ylases; 1.
DR   PANTHER; PTHR42655; GLYCOGEN PHOSPHORYLASE; 1.
DR   PANTHER; PTHR42655:SF1; GLYCOGEN PHOSPHORYLASE; 1.
DR   Pfam; PF00343; Phosphorylase; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002487}.
SQ   SEQUENCE   549 AA;  62684 MW;  E6CF9480073AE06D CRC64;
     MATIGYFSME IGLRNEIPTY AGGLGVLAGD TIRSASDLKI PLVAVTLVSN KGYFRQSLDV
     MGNQTEKIEE WTPSSFMTRT PQEVSVKIQD REVKIQAWQY NCKSLTGGCV PIIFLDTNVE
     GNAWEDRGIT DFLYGGDHTY RLKQEIVLGI GGVRMLNALG FKVRKYHMNE GHSSLLALEL
     LKCNNKDATK VKDLCIFTTH TPVEAGHDKF DYRLVDDLIR DKNDVEILRR FGGEDRFDTS
     LFALNLSNYV NGVTKRHSRV SSELFPGYSI QAITNGVHSY TWTSPFFRKL FDHYLPGWAN
     EPELLVRIGG IPDDEIWQAR RNAKKALIDE VNKRTGAGMD YETLTIGFAR RMAEYKRATL
     ILSDLERLRK INRRGRIQLI FAGKSHPNDG AGKQLIRDIF RSIETLRNEI KIVFLENYDM
     ELAAKMVSGV DVWLNTPTRP YEASGTSGMK AAHNGVVNFS VLDGWWIEGW IEGVTGWSIG
     PKPEEHLSGE EARLAELDDL YNKLYYIIVP TYYERRDEWF KLINNSIGMI AYYFNSHRMM
     RRYVTHAYL
//