ID   Q8TCR7_HUMAN            Unreviewed;       386 AA.
AC   Q8TCR7;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   02-SEP-2026, entry version 109.
DE   SubName: Full=Uncharacterized protein DKFZp761K0922 {ECO:0000313|EMBL:CAD28456.1};
DE   Flags: Fragment;
GN   Name=DKFZp761K0922 {ECO:0000313|EMBL:CAD28456.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CAD28456.1};
RN   [1] {ECO:0000313|EMBL:CAD28456.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Amygdala {ECO:0000313|EMBL:CAD28456.1};
RG   The German cDNA Consortium;
RA   Wambutt R., Heubner D., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G.,
RA   Han M., Wiemann S.;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|PROSITE-ProRule:PRU01188, ECO:0000256|RuleBase:RU000685}.
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DR   EMBL; AL713644; CAD28456.1; -; mRNA.
DR   AlphaFoldDB; Q8TCR7; -.
DR   IntAct; Q8TCR7; 2.
DR   DNASU; 4747; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0045111; C:intermediate filament cytoskeleton; IEA:UniProtKB-ARBA.
DR   FunFam; 1.20.5.170:FF:000002; Type I keratin KA11; 1.
DR   FunFam; 1.20.5.500:FF:000001; Type II keratin 23; 1.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR050405; Intermediate_filament.
DR   PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR   PANTHER; PTHR45652:SF8; NEUROFILAMENT LIGHT POLYPEPTIDE; 1.
DR   Pfam; PF00038; Filament; 1.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW   ProRule:PRU01188}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754, ECO:0000256|PROSITE-
KW   ProRule:PRU01188}.
FT   DOMAIN          1..243
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          305..386
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          23..121
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          155..221
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        314..368
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..386
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAD28456.1"
SQ   SEQUENCE   386 AA;  43779 MW;  F293388B200C7B65 CRC64;
     QNKVLEAELL VLRQKHSEPS RFRALYEQEI RDLRLAAEDA TNEKQALARA ELEKRIDSLM
     DEISFLKKVH EEEIAELQAQ IQYAQISVEM DVTKPDLSAA LKDIRAQYEK LAAKNMQNAE
     EWFKSRFTVL TESAAKNTDA VRAAKDEVSE SRRLLKAKTL EIEACRGMNE ALEKQLQELE
     DKQNADISAM QDTINKLENE LRTTKSEMAR YLKEYQDLLN VKMALDIEIA AYRKLLEGEE
     TRLSFTSVGS IISGYSQSSQ VFGRSAYGGL QTSSYLMSTR SFPSYYTSHV QEEQIEVEET
     IEAAKAEEAK DEPPSEGEAE EEEKDKEEAE EEEAAEEEEA AKEESEEAKE EEEGGEGEEG
     EETKEAEEEE KKVEGAGEEQ AAKKKD
//