ID   GLGA_FUSNN              Reviewed;         461 AA.
AC   Q8RF65;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   04-NOV-2026, entry version 111.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484}; OrderedLocusNames=FN0853;
OS   Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS   BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC   Bacteria; Fusobacteriati; Fusobacteriota; Fusobacteriia; Fusobacteriales;
OC   Fusobacteriaceae; Fusobacterium.
OX   NCBI_TaxID=190304;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 /
RC   KCTC 2640 / LMG 13131 / VPI 4355;
RX   PubMed=11889109; DOI=10.1128/jb.184.7.2005-2018.2002;
RA   Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA   Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA   Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA   Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N.C.,
RA   Overbeek R.;
RT   "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT   strain ATCC 25586.";
RL   J. Bacteriol. 184:2005-2018(2002).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AE009951; AAL95049.1; -; Genomic_DNA.
DR   RefSeq; WP_011016702.1; NZ_CP028101.1.
DR   AlphaFoldDB; Q8RF65; -.
DR   SMR; Q8RF65; -.
DR   FunCoup; Q8RF65; 69.
DR   STRING; 190304.FN0853; -.
DR   PaxDb; 190304-FN0853; -.
DR   EnsemblBacteria; AAL95049; AAL95049; FN0853.
DR   GeneID; 79783838; -.
DR   KEGG; fnu:FN0853; -.
DR   PATRIC; fig|190304.8.peg.1414; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_2_0; -.
DR   InParanoid; Q8RF65; -.
DR   OMA; AAAFYKW; -.
DR   BioCyc; FNUC190304:G1FZS-1436-MONOMER; -.
DR   UniPathway; UPA00164; -.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0009011; F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity; IBA:GO_Central.
DR   GO; GO:0004373; F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity; IEA:InterPro.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IBA:GO_Central.
DR   CDD; cd03791; GT5_Glycogen_synthase_DULL1-like; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   NCBIfam; TIGR02095; glgA; 1.
DR   PANTHER; PTHR45825:SF11; ALPHA AMYLASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45825; GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Transferase.
FT   CHAIN           1..461
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188616"
FT   BINDING         15
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   461 AA;  53586 MW;  A03722CDA94337C4 CRC64;
     MKVLFATGEA FPFVKTGGLG DVSYSLPKTL KQKENVDIRV ILPKYSKISN ELLKDARHLG
     HKEIWVAHHN EYVGIEEVEL EGVIYYFVDN ERYFKRPNVY GEFDDCERFL FFCKAVVETM
     DITKFKPDII HCNDWQSALI PIYLKERGIY DVKTIFTIHN LRFQGFFFNN VIEDLLEIDR
     AKYFQEDGLK YYDMISFLKG GVVYSDYITT VSDSYAEEIK TQELGEGIHG LFQKYDYKLS
     GIVNGIDKIS YPLSKKPHKI LKADLQKKLG LDVEEDTPLI VIITRLDRQK GLDYIVEKFD
     EMMSLGIQFI LLGTGEKRYE HFFAYQEYLH KGQVCSYIGF NQELSTEIYA GADIFLMPSV
     FEPCGLSQMI AMRYGCIPVV RETGGLKDTV KPYNEYTGEG DGFGFKQANA DDMIKTLKYA
     IKMYHRPNVW QEIIKNAKKR DNSWDKPAKR YKELYQRLIE G
//