ID   Q8MS47_DROME            Unreviewed;      1151 AA.
AC   Q8MS47;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   02-SEP-2026, entry version 112.
DE   SubName: Full=RE07981p {ECO:0000313|EMBL:AAM50964.1};
DE   Flags: Fragment;
GN   Name=Bruce {ECO:0000313|EMBL:AAM50964.1,
GN   ECO:0000313|FlyBase:FBgn0266717};
GN   ORFNames=CG6303 {ECO:0000313|FlyBase:FBgn0266717};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Altocrustacea; Allotriocarida;
OC   Hexapoda; Insecta; Pterygota; Neoptera; Eumetabola; Endopterygota;
OC   Aparaglossata; Panorpida; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AAM50964.1};
RN   [1] {ECO:0000313|EMBL:AAM50964.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Berkeley {ECO:0000313|EMBL:AAM50964.1};
RA   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M.,
RA   Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.,
RA   Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A.,
RA   Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S.,
RA   Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.;
RL   Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AY119104; AAM50964.1; -; mRNA.
DR   AlphaFoldDB; Q8MS47; -.
DR   MEROPS; I32.006; -.
DR   AGR; FB:FBgn0266717; -.
DR   FlyBase; FBgn0266717; Bruce.
DR   VEuPathDB; VectorBase:FBgn0266717; -.
DR   HOGENOM; CLU_000111_1_0_1; -.
DR   OrthoDB; 47801at2759; -.
DR   ExpressionAtlas; Q8MS47; baseline and differential.
DR   CDD; cd00022; BIR; 1.
DR   FunFam; 1.10.1170.10:FF:000001; baculoviral IAP repeat-containing protein 6 isoform X1; 1.
DR   Gene3D; 1.10.1170.10; Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A; 1.
DR   InterPro; IPR051190; Baculoviral_IAP.
DR   InterPro; IPR001370; BIR_rpt.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR46771; DETERIN; 1.
DR   PANTHER; PTHR46771:SF5; DETERIN; 1.
DR   Pfam; PF00653; BIR; 1.
DR   SMART; SM00238; BIR; 1.
DR   SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50143; BIR_REPEAT_2; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00029};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00029}.
FT   REPEAT          251..321
FT                   /note="BIR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00029"
FT   REGION          502..527
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          645..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        503..515
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         290
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00029"
FT   BINDING         293
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00029"
FT   BINDING         310
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00029"
FT   BINDING         317
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00029"
FT   NON_TER         1151
FT                   /evidence="ECO:0000313|EMBL:AAM50964.1"
SQ   SEQUENCE   1151 AA;  126537 MW;  EB1F46022AD5D4DD CRC64;
     MATEQHHQQR VLKQDGYLDL GDCNSAPSRP FEMRNVVYHP QLNVLLLFDN GSTVKVLDAN
     SGVILQTYHL SSNGDSIVHG RYMPLQDKIL FWDGHNLGLR GDYNGVLLLD TILQAPIGQN
     DDYIKLEIIL SEAIIFQNCI TELESEGLEC PCDISNELTQ KINQAQLKAK KGIKAQRWNT
     ICLEVPYSSL KLVSNNMVIL LKRLERHIPV LAIASAINER LTDMMMGSRV PDFGWNFSNF
     QRVLMHSEAV RRQTFEKWPH MDYKWALPDQ MAQAGFYHQP SSSGEDRAMC FTCSVCLVCW
     EKTDEPWSEH ERHSPLCPFV KGEYTQNVPL SITYATNPAL PAPGLGFDII SNSDYANVLC
     TSCSQTGELS VWSIERHLKL MHTFHVPTLL NYIFEESFEW ARVTAICVLP NARARTKVNY
     VYSAANYGGS GSSNGAGCNS GLNAVSGGKF GSVSAQHITS TSTLRAGVVG SKIVLGVSVR
     QSSGELALRM VVLNIVEVDR NSESSTSVSN DSGSVSSGGG QLMKSSSPMV NVSAESNATV
     TQVNLESKDD DNKAMTPYEK FADGFDSNGF VSALMTYNKN NGVSQNTDDA SALYDFDLCT
     LSQILDHNLE EPLSLMVGSS NTVNVSNIGM GNEINKLVVD VEISHQNNNN NNNNNNEASS
     LGGNSSNNNN NIMINGGTNS SIDKMTAIEE IDCVVESWTS VKRMNALDGA SSGVNGVNHM
     DQEVIEIAEI LPTTPKCNQL LVKLLRTKAP EAEGSKIIMA TVAKEEEEED EEQRTDESME
     TDNNAEGNVA AQLLVFDYDD TEISNDYTLA MTFSRAKFPK QLCILPHFNS SPEHKDAGSI
     CVVCADGTVE IYSLADFQGT MVIEEEGEHF ESVVYCRNLD RLCCCSRQGG LLFYSLSDGE
     NDSGDELLEM DDDCSTTLTQ AADVSVTDGG RQLARTDLLG KTLLANESIC MDAGSEAAAI
     PNSSSAAQGA HVQTSPSASS APSTNANLLA YKTADLTLED LKVFYALTQF DDKLTVYSAE
     VPSCWNDIGQ VQNQRKQSQN MRHGGDERDF TRTWRLHNDA TTWDEHIIEL NLAQPVSLGH
     IDLKFTVYQQ CSNPAAIQVT LLKQNNNGFG YRMKGPHSSY KPNVIDDNID LSYIANENPV
     LSEEYLQKKK K
//