ID   Q8MS26_DROME            Unreviewed;       113 AA.
AC   Q8MS26;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   02-SEP-2026, entry version 87.
DE   RecName: Full=ER membrane protein complex subunit 6 {ECO:0000256|ARBA:ARBA00020827};
DE   AltName: Full=Transmembrane protein 93 {ECO:0000256|ARBA:ARBA00031072};
GN   Name=EMC6 {ECO:0000313|FlyBase:FBgn0039259};
GN   ORFNames=CG11781 {ECO:0000313|FlyBase:FBgn0039259};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Altocrustacea; Allotriocarida;
OC   Hexapoda; Insecta; Pterygota; Neoptera; Eumetabola; Endopterygota;
OC   Aparaglossata; Panorpida; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AAM50994.1};
RN   [1] {ECO:0000313|EMBL:AAM50994.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Berkeley {ECO:0000313|EMBL:AAM50994.1};
RA   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M.,
RA   Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.,
RA   Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A.,
RA   Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S.,
RA   Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.;
RL   Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}.
CC   -!- SIMILARITY: Belongs to the EMC6 family.
CC       {ECO:0000256|ARBA:ARBA00009436}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY119134; AAM50994.1; -; mRNA.
DR   AlphaFoldDB; Q8MS26; -.
DR   AGR; FB:FBgn0039259; -.
DR   FlyBase; FBgn0039259; EMC6.
DR   VEuPathDB; VectorBase:FBgn0039259; -.
DR   HOGENOM; CLU_110781_3_0_1; -.
DR   OrthoDB; 16510at2759; -.
DR   ExpressionAtlas; Q8MS26; baseline and differential.
DR   GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR   InterPro; IPR008504; Emc6.
DR   InterPro; IPR029008; EMC6-like.
DR   PANTHER; PTHR20994; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6; 1.
DR   PANTHER; PTHR20994:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6; 1.
DR   Pfam; PF07019; EMC6; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        55..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        92..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   113 AA;  12730 MW;  A67BCB4581A75838 CRC64;
     MNRVKTTQSK TGEIIAYSEG AIRNNISAVE YCRTSMAAIS GCAAGILGLS GTLGFLFYFL
     SVFVLWILVL VKSGTQWRKF FINRRNLLTN QFMGGLCTYV LFWTFLYGMA HVY
//