ID   PPR3_ARATH              Reviewed;         524 AA.
AC   Q8LPS6; O23677;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 2.
DT   02-SEP-2026, entry version 119.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At1g02150;
GN   OrderedLocusNames=At1g02150; ORFNames=T6A9.13, T7I23.8;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Resource (TAIR);
RT   "Community-consensus reference genome of Arabidopsis thaliana Col-0.";
RL   Submitted (FEB-2026) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA   Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA   Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
CC   -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC       URL="https://ppr.plantenergy.uwa.edu.au";
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DR   EMBL; AC064879; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U89959; AAC24372.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE27393.1; -; Genomic_DNA.
DR   EMBL; OZ408683; CAO7025750.1; -; Genomic_DNA.
DR   EMBL; AY094410; AAM19786.1; -; mRNA.
DR   EMBL; BT005812; AAO64747.1; -; mRNA.
DR   RefSeq; NP_171717.2; NM_100095.4.
DR   AlphaFoldDB; Q8LPS6; -.
DR   SMR; Q8LPS6; -.
DR   BioGRID; 24812; 1.
DR   FunCoup; Q8LPS6; 830.
DR   STRING; 3702.Q8LPS6; -.
DR   PaxDb; 3702-Q8LPS6; -.
DR   ProteomicsDB; 236587; -.
DR   GeneID; 839577; -.
DR   KEGG; ath:AT1G02150; -.
DR   Araport; AT1G02150; -.
DR   TAIR; AT1G02150; -.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_019802_3_0_1; -.
DR   InParanoid; Q8LPS6; -.
DR   OMA; YDPRICN; -.
DR   PhylomeDB; Q8LPS6; -.
DR   PRO; PR:Q8LPS6; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q8LPS6; baseline and differential.
DR   GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR   GO; GO:0005739; C:mitochondrion; ISM:TAIR.
DR   GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR   FunFam; 1.25.40.10:FF:000253; Pentatricopeptide repeat-containing protein; 1.
DR   FunFam; 1.25.40.10:FF:000516; Pentatricopeptide repeat-containing protein; 1.
DR   FunFam; 1.25.40.10:FF:000743; Pentatricopeptide repeat-containing protein; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR002885; PPR_rpt.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   NCBIfam; TIGR00756; PPR; 3.
DR   PANTHER; PTHR45717:SF3; OS04G0544400 PROTEIN; 1.
DR   PANTHER; PTHR45717; OS12G0527900 PROTEIN; 1.
DR   Pfam; PF01535; PPR; 3.
DR   Pfam; PF13812; PPR_3; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS51375; PPR; 7.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..524
FT                   /note="Pentatricopeptide repeat-containing protein
FT                   At1g02150"
FT                   /id="PRO_0000342744"
FT   REPEAT          168..202
FT                   /note="PPR 1"
FT   REPEAT          203..237
FT                   /note="PPR 2"
FT   REPEAT          238..268
FT                   /note="PPR 3"
FT   REPEAT          274..304
FT                   /note="PPR 4"
FT   REPEAT          309..339
FT                   /note="PPR 5"
FT   REPEAT          344..378
FT                   /note="PPR 6"
FT   REPEAT          379..413
FT                   /note="PPR 7"
FT   CONFLICT        119
FT                   /note="L -> I (in Ref. 4; AAO64747/AAM19786)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   524 AA;  59883 MW;  3A9FDD26BD9FE1E6 CRC64;
     MLLQAAVQNR NVPLASSASY SRLLRCRSPV VSVAALSKKT AAIVCSISQV YGYGTVDYER
     RPIVQWNAIY KKISLMEKPE LGAASVLNQW EKAGRKLTKW ELCRVVKELR KYKRANQALE
     VYDWMNNRGE RFRLSASDAA IQLDLIGKVR GIPDAEEFFL QLPENFKDRR VYGSLLNAYV
     RAKSREKAEA LLNTMRDKGY ALHPLPFNVM MTLYMNLREY DKVDAMVFEM KQKDIRLDIY
     SYNIWLSSCG SLGSVEKMEL VYQQMKSDVS IYPNWTTFST MATMYIKMGE TEKAEDALRK
     VEARITGRNR IPYHYLLSLY GSLGNKKELY RVWHVYKSVV PSIPNLGYHA LVSSLVRMGD
     IEGAEKVYEE WLPVKSSYDP RIPNLLMNAY VKNDQLETAE GLFDHMVEMG GKPSSSTWEI
     LAVGHTRKRC ISEALTCLRN AFSAEGSSNW RPKVLMLSGF FKLCEEESDV TSKEAVLELL
     RQSGDLEDKS YLALIDVDEN RTVNNSEIDA HETDALLTQL QDDL
//