Q8K9T9 ODP1_BUCAP Pyruvate dehydrogenase E1 component PDH E1 component 1.2.4.1 aceE BUsg_199 Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Enterobacterales Erwiniaceae Buchnera NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] Sg Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2 thiamine diphosphate Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Oxidoreductase Pyruvate Reference proteome Thiamine pyrophosphate MSEKLYNYDVDPVETNDWVQSIESVIREEGLERAKFLIEKILKKSKITRANFFKCFFTSDYINTISSEEEVEYPGDLILEKRIRSAIRWNAIMMVLRASKKDLELGGHLSSFQSSATIYEVCFNHFFRSKNDEDGGDLVYFQGHIAPGIYARSFLEGRLSKKQIDNFRQEVDGKGLSSYPHPKLMPNFWQFPTVSMGLGPLCAIYQAKFLKYLQNRELKNTSKQTVYAFLGDGEMDEPESKGAISIAVREKLDNLIFVINCNLQRLDGPVVGNGKIVNELESFFYGAGWKVIKVIWGGKWDSLLKKDKTGKLIQLMNETIDGEYQTLKSKDGAYVRKYFFGKYQETLELVKNMTDEEIWNLNRGGHDPKKMFNALKKAKEIKDKPTVILAHTVKGYGMGVIAEGKNIAHQIKKININGIIYIRDRFNIPISNEDIKELPYVVFEKNSKEYCYMHQQRKKLGGYIPFRLSKFTNALNIPDLIDFKSLLKEQNKKMSTTIAFVRVLNLILKNHSIKNLIVPIIADEARTFGMEGLFRMIGIYSSIGQKYVPQDREQLAYYKEEKKGQILQEGINELGAASSWLAAATSYSTNDFPMIPFYIYYSIFGFQRIGDLFWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCVSYDPAFAYEVAVIIQDGLRRMYGPLQENIYYYITTINENYYMPAMPQGVEKGICKGIYKLKTFYATELKVQLMGSGAILRCICKAGEILSNDYCITTDIYSVTSFTELARNGEDCERWNMLHPYEKKRIAYIKTVMNSSPAVAATDYMKLFAEQIRHYIPSNEYHVLGTDGFGRSDSRDKLRDHFEVSAYYIVVAALNLLAKLNNINKKVVEEAIIKFNINADKINPRLA Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License