ID   CMA1C_HUMAN             Reviewed;         274 AA.
AC   Q8IXM7;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   28-JAN-2026, entry version 121.
DE   RecName: Full=Ciliary microtubule associated protein 1C {ECO:0000312|HGNC:HGNC:28735};
DE   AltName: Full=Outer dense fiber protein 3-like protein 1;
DE   AltName: Full=Protein CIMAP1C {ECO:0000305};
GN   Name=CIMAP1C {ECO:0000312|HGNC:HGNC:28735}; Synonyms=ODF3L1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- INTERACTION:
CC       Q8IXM7; O95429: BAG4; NbExp=3; IntAct=EBI-13331299, EBI-2949658;
CC       Q8IXM7; A8MQ03: CYSRT1; NbExp=3; IntAct=EBI-13331299, EBI-3867333;
CC   -!- SIMILARITY: Belongs to the CIMAP family. {ECO:0000305}.
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DR   EMBL; CH471136; EAW99238.1; -; Genomic_DNA.
DR   EMBL; BC039862; AAH39862.1; -; mRNA.
DR   CCDS; CCDS10285.1; -.
DR   RefSeq; NP_787077.1; NM_175881.5.
DR   AlphaFoldDB; Q8IXM7; -.
DR   BioGRID; 127801; 11.
DR   FunCoup; Q8IXM7; 26.
DR   IntAct; Q8IXM7; 10.
DR   STRING; 9606.ENSP00000329584; -.
DR   GlyGen; Q8IXM7; 2 sites, 1 O-linked glycan (1 site).
DR   iPTMnet; Q8IXM7; -.
DR   PhosphoSitePlus; Q8IXM7; -.
DR   BioMuta; ODF3L1; -.
DR   DMDM; 74728213; -.
DR   MassIVE; Q8IXM7; -.
DR   PaxDb; 9606-ENSP00000329584; -.
DR   PeptideAtlas; Q8IXM7; -.
DR   ProteomicsDB; 71032; -.
DR   Antibodypedia; 27373; 50 antibodies from 14 providers.
DR   DNASU; 161753; -.
DR   Ensembl; ENST00000332145.3; ENSP00000329584.2; ENSG00000182950.3.
DR   GeneID; 161753; -.
DR   KEGG; hsa:161753; -.
DR   MANE-Select; ENST00000332145.3; ENSP00000329584.2; NM_175881.5; NP_787077.1.
DR   UCSC; uc002bax.2; human.
DR   AGR; HGNC:28735; -.
DR   ClinPGx; PA134930463; -.
DR   CTD; 161753; -.
DR   GeneCards; CIMAP1C; -.
DR   HGNC; HGNC:28735; CIMAP1C.
DR   HPA; ENSG00000182950; Tissue enriched (testis).
DR   OpenTargets; ENSG00000182950; -.
DR   VEuPathDB; HostDB:ENSG00000182950; -.
DR   eggNOG; ENOG502S2VQ; Eukaryota.
DR   GeneTree; ENSGT00940000162054; -.
DR   HOGENOM; CLU_088282_1_0_1; -.
DR   InParanoid; Q8IXM7; -.
DR   OMA; YTLHTRH; -.
DR   OrthoDB; 429991at2759; -.
DR   PAN-GO; Q8IXM7; 1 GO annotation based on evolutionary models.
DR   PhylomeDB; Q8IXM7; -.
DR   PathwayCommons; Q8IXM7; -.
DR   SignaLink; Q8IXM7; -.
DR   Agora; ENSG00000182950; -.
DR   BioGRID-ORCS; 161753; 11 hits in 1140 CRISPR screens.
DR   GenomeRNAi; 161753; -.
DR   Pharos; Q8IXM7; Tdark.
DR   PRO; PR:Q8IXM7; -.
DR   Proteomes; UP000005640; Chromosome 15.
DR   RNAct; Q8IXM7; protein.
DR   Bgee; ENSG00000182950; Expressed in left testis and 93 other cell types or tissues.
DR   GO; GO:0005856; C:cytoskeleton; IBA:GO_Central.
DR   InterPro; IPR051291; CIMAP.
DR   InterPro; IPR010736; SHIPPO-rpt.
DR   PANTHER; PTHR21580:SF3; OUTER DENSE FIBER PROTEIN 3-LIKE PROTEIN 1; 1.
DR   PANTHER; PTHR21580; SHIPPO-1-RELATED; 1.
DR   Pfam; PF07004; SHIPPO-rpt; 4.
PE   1: Evidence at protein level;
KW   Proteomics identification; Reference proteome; Repeat.
FT   CHAIN           1..274
FT                   /note="Ciliary microtubule associated protein 1C"
FT                   /id="PRO_0000304785"
FT   REPEAT          199..224
FT                   /note="STPGR 1"
FT   REPEAT          235..260
FT                   /note="STPGR 2"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..27
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         41
FT                   /note="P -> L (in dbSNP:rs55905564)"
FT                   /id="VAR_062204"
SQ   SEQUENCE   274 AA;  31065 MW;  158ACA014D428CBF CRC64;
     MKLPKGTRSS VYFAQHPEKE PLPSRQEVKQ TPVIMAKIKG PGPAKYLRPS CTGYIDHDIS
     MFKAPAYTLH SRHSEKRMVC HSSPGPCYLL DPKITRFGMS SCPQVPMEER ISNLRLNPTL
     ASCQYYFEKI HPPGERRAPQ YTFGYRRPYR VMDLNPAPNQ YQMPLLLGPN TPVSRAAPCY
     SLASRDKNWF YKEDVAGGPG PTTYARPEPS IYQNRSPTYS MAKRFAYPLD LTPRPGPGSH
     EVQQVTVHKP HIPAFTMGIK HSLHLCPLVI DIRD
//