ID   Q82K33_STRAW            Unreviewed;       237 AA.
AC   Q82K33;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   02-SEP-2026, entry version 113.
DE   SubName: Full=Sugar hydrolase, secreted {ECO:0000313|EMBL:BAC70282.1};
GN   ORFNames=SAVERM_2571 {ECO:0000313|EMBL:BAC70282.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC70282.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC70282.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC70282.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
RN   [3] {ECO:0000313|EMBL:BAC70282.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=23990133; DOI=10.1007/s10295-013-1327-x;
RA   Ikeda H., Shin-ya K., Omura S.;
RT   "Genome mining of the Streptomyces avermitilis genome and development of
RT   genome-minimized hosts for heterologous expression of biosynthetic gene
RT   clusters.";
RL   J. Ind. Microbiol. Biotechnol. 41:233-250(2014).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 12 (cellulase H) family.
CC       {ECO:0000256|ARBA:ARBA00005519, ECO:0000256|RuleBase:RU361163}.
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DR   EMBL; BA000030; BAC70282.1; -; Genomic_DNA.
DR   RefSeq; WP_010984007.1; NC_003155.5.
DR   AlphaFoldDB; Q82K33; -.
DR   GeneID; 41539658; -.
DR   KEGG; sma:SAVERM_2571; -.
DR   eggNOG; COG5297; Bacteria.
DR   HOGENOM; CLU_051064_2_1_11; -.
DR   OrthoDB; 8885070at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0008810; F:cellulase activity; IEA:InterPro.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.180; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR013319; GH11/12.
DR   InterPro; IPR002594; GH12.
DR   NCBIfam; NF004860; PRK06215.1; 1.
DR   PANTHER; PTHR34002; BLR1656 PROTEIN; 1.
DR   PANTHER; PTHR34002:SF9; XYLOGLUCAN-SPECIFIC ENDO-BETA-1,4-GLUCANASE A; 1.
DR   Pfam; PF01670; Glyco_hydro_12; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|RuleBase:RU361163};
KW   Glycosidase {ECO:0000256|RuleBase:RU361163};
KW   Hydrolase {ECO:0000256|RuleBase:RU361163, ECO:0000313|EMBL:BAC70282.1};
KW   Polysaccharide degradation {ECO:0000256|RuleBase:RU361163};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           34..237
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004296938"
SQ   SEQUENCE   237 AA;  24911 MW;  A33180657C7D15B5 CRC64;
     MAPRTLSKVT KALIAPALAL GATIGLASAP AQAAVWSSCD QWGNTTLNGY TLYNNIWGSG
     AGSQCIWANS GTNWGVNANH PNTGGIKSYP NAKKVINKSI TSLGSLSSSY NVTVPSSGAY
     NTSYDIWDTA YKYEVMLWVN YNGAVGALGT SQGNLTLGGH TWTVYKGNNG SNDVFSFLRT
     SDSSSGTVNV LPILKWIKDT KGWFGNVTIG DVQFGFEITS SSGGLDFTTN SLSVSSS
//