ID   Q82CC2_STRAW            Unreviewed;       391 AA.
AC   Q82CC2;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   04-NOV-2026, entry version 111.
DE   SubName: Full=Magnesium or manganese-dependent protein phosphatase {ECO:0000313|EMBL:BAC73141.1};
GN   Name=prpB11 {ECO:0000313|EMBL:BAC73141.1};
GN   ORFNames=SAVERM_5429 {ECO:0000313|EMBL:BAC73141.1};
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC73141.1, ECO:0000313|Proteomes:UP000000428};
RN   [1] {ECO:0000313|EMBL:BAC73141.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2] {ECO:0000313|EMBL:BAC73141.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
RN   [3] {ECO:0000313|EMBL:BAC73141.1, ECO:0000313|Proteomes:UP000000428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC   NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX   PubMed=23990133; DOI=10.1007/s10295-013-1327-x;
RA   Ikeda H., Shin-ya K., Omura S.;
RT   "Genome mining of the Streptomyces avermitilis genome and development of
RT   genome-minimized hosts for heterologous expression of biosynthetic gene
RT   clusters.";
RL   J. Ind. Microbiol. Biotechnol. 41:233-250(2014).
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DR   EMBL; BA000030; BAC73141.1; -; Genomic_DNA.
DR   RefSeq; WP_010986832.1; NC_003155.5.
DR   AlphaFoldDB; Q82CC2; -.
DR   GeneID; 41542520; -.
DR   KEGG; sma:SAVERM_5429; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_745515_0_0_11; -.
DR   OMA; ACGTIWR; -.
DR   OrthoDB; 4291756at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016791; F:phosphatase activity; IEA:TreeGrafter.
DR   FunFam; 3.60.40.10:FF:000039; Stage II sporulation protein E; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR052016; Bact_Sigma-Reg.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        44..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          174..383
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   391 AA;  41561 MW;  ABB98E737C75EA5D CRC64;
     MAAGRERRAA AETFTARLKK QWHRARTGVR RSAVDYFRGD GSDWIALAGL LLTIPLIAAT
     TLMNSVWCSP AALVLPIVAG GLLLRPSSLL GLYAAAASAL IVESVKLGPY TEGPSRVTPG
     VVLVVAACGF FGLLIAQFRS RVGVPWRRGG TMLFDLRERI RVQSKLPKLP LGWHREMALR
     PAGGQSFSGD FVVAARTNGG RTLEVVLTDV SGKGMDAGSR ALLLSGAFGG LLGSLPPHAF
     LPAANGYLLR QDWDEGFATS IHLVLELDSG DYELFSAGHP PGLQLSAGSG RWEEKAAEGP
     LLGVYDGAQF DPVKGSLRPG DVLMLFTDGL VETAERDIVE GIDRLTGEAD RYVAGGFHGA
     AWHLIEAVAK DVNDDRALLL VCRDGPTAAA R
//