ID   Q7NMD6_GLOVI            Unreviewed;       205 AA.
AC   Q7NMD6;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   28-JAN-2026, entry version 132.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000256|HAMAP-Rule:MF_00948, ECO:0000256|NCBIfam:TIGR00922};
GN   Name=nusG {ECO:0000256|HAMAP-Rule:MF_00948,
GN   ECO:0000313|EMBL:BAC88771.1};
OS   Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC   Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Gloeobacterales;
OC   Gloeobacteraceae; Gloeobacter.
OX   NCBI_TaxID=251221 {ECO:0000313|EMBL:BAC88771.1, ECO:0000313|Proteomes:UP000000557};
RN   [1] {ECO:0000313|EMBL:BAC88771.1, ECO:0000313|Proteomes:UP000000557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29082 / PCC 7421 {ECO:0000313|Proteomes:UP000000557};
RX   PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA   Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA   Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA   Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT   cyanobacterium that lacks thylakoids.";
RL   DNA Res. 10:137-145(2003).
RN   [2] {ECO:0000313|EMBL:BAC88771.1, ECO:0000313|Proteomes:UP000000557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29082 / PCC 7421 {ECO:0000313|Proteomes:UP000000557};
RX   PubMed=14621296; DOI=10.1093/dnares/10.4.181;
RA   Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA   Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA   Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT   cyanobacterium that lacks thylakoids (supplement).";
RL   DNA Res. 10:181-201(2003).
CC   -!- FUNCTION: Participates in transcription elongation, termination and
CC       antitermination. {ECO:0000256|HAMAP-Rule:MF_00948,
CC       ECO:0000256|RuleBase:RU000538}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000256|HAMAP-
CC       Rule:MF_00948, ECO:0000256|RuleBase:RU000538}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000045; BAC88771.1; -; Genomic_DNA.
DR   RefSeq; WP_011140832.1; NC_005125.1.
DR   AlphaFoldDB; Q7NMD6; -.
DR   FunCoup; Q7NMD6; 145.
DR   STRING; 251221.gene:10758308; -.
DR   EnsemblBacteria; BAC88771; BAC88771; BAC88771.
DR   KEGG; gvi:glr0830; -.
DR   PATRIC; fig|251221.4.peg.848; -.
DR   eggNOG; COG0250; Bacteria.
DR   HOGENOM; CLU_067287_1_1_3; -.
DR   InParanoid; Q7NMD6; -.
DR   OrthoDB; 9809075at2; -.
DR   PhylomeDB; Q7NMD6; -.
DR   Proteomes; UP000000557; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0006354; P:DNA-templated transcription elongation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   CDD; cd06091; KOW_NusG; 1.
DR   CDD; cd09891; NGN_Bact_1; 1.
DR   FunFam; 2.30.30.30:FF:000002; Transcription termination/antitermination factor NusG; 1.
DR   FunFam; 3.30.70.940:FF:000006; Transcription termination/antitermination protein NusG; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; NusG, N-terminal domain; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR047050; NGN.
DR   InterPro; IPR006645; NGN-like_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR043425; NusG-like.
DR   InterPro; IPR014722; Rib_uL2_dom2.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR015869; Transcrpt_antiterm_NusG_bac_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   NCBIfam; TIGR00922; nusG; 1.
DR   PANTHER; PTHR30265; RHO-INTERACTING TRANSCRIPTION TERMINATION FACTOR NUSG; 1.
DR   PANTHER; PTHR30265:SF2; TRANSCRIPTION TERMINATION_ANTITERMINATION PROTEIN NUSG; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF02357; NusG; 1.
DR   PRINTS; PR00338; NUSGTNSCPFCT.
DR   SMART; SM00739; KOW; 1.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF82679; N-utilization substance G protein NusG, N-terminal domain; 1.
DR   SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
DR   PROSITE; PS01014; NUSG; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000557};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW   Rule:MF_00948};
KW   Transcription antitermination {ECO:0000256|ARBA:ARBA00022814,
KW   ECO:0000256|HAMAP-Rule:MF_00948};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW   Rule:MF_00948};
KW   Transcription termination {ECO:0000256|ARBA:ARBA00022472,
KW   ECO:0000256|HAMAP-Rule:MF_00948}.
FT   DOMAIN          19..139
FT                   /note="NusG-like N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00738"
FT   DOMAIN          149..176
FT                   /note="KOW"
FT                   /evidence="ECO:0000259|SMART:SM00739"
SQ   SEQUENCE   205 AA;  23404 MW;  AEA69D70A1240BFB CRC64;
     MVIGTDFLMD SARKPEQPEP HWYFVQVASG CEKKVKTNLE QRIQTMEMSE RILKVEIPER
     QAVRIRQEGS RTASAEKIFP GYVLINMVMD DESWQVVKNT PNVINFVGTE ERRRYGRGRG
     HVTPRPLGSA EVNRIFRAAE QEEPVIKVDL EPGHKIEVTA GPFQDFNGEV VEVNPERGTL
     KALISIFGRD TPVELGFNQV RRLDE
//