ID   Q7CWF2_AGRFC            Unreviewed;       337 AA.
AC   Q7CWF2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 2.
DT   28-JAN-2026, entry version 97.
DE   SubName: Full=ABC transporter, substrate binding protein (Thiamine) {ECO:0000313|EMBL:AAK88432.2};
GN   Name=thiB {ECO:0000313|EMBL:AAK88432.2};
GN   OrderedLocusNames=Atu2714 {ECO:0000313|EMBL:AAK88432.2};
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Hyphomicrobiales; Rhizobiaceae; Rhizobium/Agrobacterium group;
OC   Agrobacterium; Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK88432.2, ECO:0000313|Proteomes:UP000000813};
RN   [1] {ECO:0000313|EMBL:AAK88432.2, ECO:0000313|Proteomes:UP000000813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [2] {ECO:0000313|EMBL:AAK88432.2, ECO:0000313|Proteomes:UP000000813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 1 family.
CC       {ECO:0000256|ARBA:ARBA00008520}.
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DR   EMBL; AE007869; AAK88432.2; -; Genomic_DNA.
DR   RefSeq; WP_010972512.1; NC_003062.2.
DR   AlphaFoldDB; Q7CWF2; -.
DR   STRING; 176299.Atu2714; -.
DR   EnsemblBacteria; AAK88432; AAK88432; Atu2714.
DR   GeneID; 1134752; -.
DR   KEGG; atu:Atu2714; -.
DR   PATRIC; fig|176299.10.peg.2722; -.
DR   eggNOG; COG4143; Bacteria.
DR   HOGENOM; CLU_026974_6_0_5; -.
DR   OrthoDB; 8013425at2; -.
DR   PhylomeDB; Q7CWF2; -.
DR   BioCyc; AGRO:ATU2714-MONOMER; -.
DR   Proteomes; UP000000813; Chromosome circular.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0030975; F:thiamine binding; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:TreeGrafter.
DR   GO; GO:0015888; P:thiamine transport; IEA:InterPro.
DR   CDD; cd13545; PBP2_TbpA; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR005967; ThiB.
DR   InterPro; IPR005948; ThiB-like.
DR   NCBIfam; TIGR01254; sfuA; 1.
DR   NCBIfam; TIGR01276; thiB; 1.
DR   PANTHER; PTHR30006:SF3; THIAMINE-BINDING PERIPLASMIC PROTEIN; 1.
DR   PANTHER; PTHR30006; THIAMINE-BINDING PERIPLASMIC PROTEIN-RELATED; 1.
DR   Pfam; PF13343; SBP_bac_6; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   3: Inferred from homology;
KW   Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000813};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..337
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004287095"
SQ   SEQUENCE   337 AA;  36750 MW;  BB15B29DC4D7462F CRC64;
     MRRRLFLNSV IAASLFLPGL AAAQDKPELT VYTYESFVSE WGPGPKVKEA FEKVCVCTVN
     FVGVADGVAL LNRLKLEGSG SKADVVVGLD TNLVAEAKQT GLFDASGIDA SAAKVPGGYK
     DDVFVPYDYG HFAVIYDTQA VKNPPASLKE LVEGDSAQKI AIQDPRTSTP GLGLLLWVKS
     VYGDKAPEAW AKLRKRILTV TPGWSESYGL FTKGEVPMVL SYTTSPAYHM VAEKSDRYQA
     AAFSEGHYIQ IEVSGLLKNA PHKELAKQFL AFTLTSGFQD AIPENNWMMP VAATSAPLPE
     AFSKLVVPQK TFLMDPEEVA KNRKAWIDEW LSAMSMN
//