ID   Q74EC2_GEOSL            Unreviewed;       541 AA.
AC   Q74EC2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   02-SEP-2026, entry version 110.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 40H {ECO:0000313|EMBL:AAR34367.1};
GN   Name=mcp40H-25 {ECO:0000313|EMBL:AAR34367.1};
GN   OrderedLocusNames=GSU1041 {ECO:0000313|EMBL:AAR34367.1};
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfuromonadia;
OC   Geobacterales; Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR34367.1, ECO:0000313|Proteomes:UP000000577};
RN   [1] {ECO:0000313|EMBL:AAR34367.1, ECO:0000313|Proteomes:UP000000577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA
RC   {ECO:0000313|Proteomes:UP000000577};
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA   Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA   Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA   Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA   Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
RN   [2] {ECO:0000313|EMBL:AAR34367.1, ECO:0000313|Proteomes:UP000000577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA
RC   {ECO:0000313|Proteomes:UP000000577};
RX   PubMed=22967216; DOI=10.1186/1471-2164-13-471;
RA   Butler J.E., Young N.D., Aklujkar M., Lovley D.R.;
RT   "Comparative genomic analysis of Geobacter sulfurreducens KN400, a strain
RT   with enhanced capacity for extracellular electron transfer and electricity
RT   production.";
RL   BMC Genomics 13:471-471(2012).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017180; AAR34367.1; -; Genomic_DNA.
DR   RefSeq; WP_010941702.1; NC_002939.5.
DR   AlphaFoldDB; Q74EC2; -.
DR   SMR; Q74EC2; -.
DR   FunCoup; Q74EC2; 201.
DR   STRING; 243231.GSU1041; -.
DR   EnsemblBacteria; AAR34367; AAR34367; GSU1041.
DR   KEGG; gsu:GSU1041; -.
DR   PATRIC; fig|243231.5.peg.1039; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   InParanoid; Q74EC2; -.
DR   OrthoDB; 9791237at2; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   FunFam; 1.10.287.950:FF:000001; Methyl-accepting chemotaxis sensory transducer; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF112; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          210..262
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          267..503
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   541 AA;  57575 MW;  570E842668FF7326 CRC64;
     MFMRNWKIGT KLATGFGGLL LLLVIFTTVT IISIRFVKTS TSQIRTESLP YALLAEEMAF
     EVVQVQQFLT DVGATREPDA YAEADAAAAN FRKSLKQFED MYRRENDTAA LQSVEKMEKD
     FESFYQLGRR MAEAYMAEGT EAGNRLMGDF DKVSTVLAED MRTFKEGQVR EANHMTASVD
     ETLGGLEKVI IALAAAGIIV GLFASWFIGK AISAPLGKAV SAIDRIASGD LTIRIPVTGS
     DETGALAVSV NRMADDMGTA MAALANASSH LASASVELAV QADQMAKGAE EVAAQTGTVA
     AASEEMAATS HEIAMNCSHA AESSRRANDR ASAGSDVIRR TVEGMHRIAE KVQRSSESVA
     GLGARSDQIG QIVSVIEDIA DQTNLLALNA AIEAARAGEQ GRGFAVVADE VRALAERTGK
     ATREIAQMIR SIQQETEGAV KAMEEGVAEV SAGKEDAQQS AGALREIVEQ IEAMTTQINQ
     IAVASEQQNA TTDQITMNLQ QVSSVIEASS RGSEETANAA HTLSALSEEL QSIVGRFRTA
     A
//