ID   Q73RC1_TREDE            Unreviewed;       552 AA.
AC   Q73RC1;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   02-SEP-2026, entry version 83.
DE   SubName: Full=Methyl-accepting chemotaxis domain protein {ECO:0000313|EMBL:AAS10666.1};
GN   OrderedLocusNames=TDE_0169 {ECO:0000313|EMBL:AAS10666.1};
OS   Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153
OS   / KCTC 15104).
OC   Bacteria; Pseudomonadati; Spirochaetota; Spirochaetia; Treponematales;
OC   Treponemataceae; Treponema.
OX   NCBI_TaxID=243275 {ECO:0000313|EMBL:AAS10666.1, ECO:0000313|Proteomes:UP000008212};
RN   [1] {ECO:0000313|EMBL:AAS10666.1, ECO:0000313|Proteomes:UP000008212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104
RC   {ECO:0000313|Proteomes:UP000008212};
RX   PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA   Seshadri R., Myers G.S., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA   Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J.,
RA   Ren Q., Brinkac L.M., Madupu R., Kolonay J., Durkin S.A., Daugherty S.C.,
RA   Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.,
RA   Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S.,
RA   Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E.,
RA   Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
RT   "Comparison of the genome of the oral pathogen Treponema denticola with
RT   other spirochete genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017226; AAS10666.1; -; Genomic_DNA.
DR   RefSeq; WP_002681051.1; NC_002967.9.
DR   AlphaFoldDB; Q73RC1; -.
DR   STRING; 243275.TDE_0169; -.
DR   PaxDb; 243275-TDE_0169; -.
DR   GeneID; 2739521; -.
DR   KEGG; tde:TDE_0169; -.
DR   PATRIC; fig|243275.7.peg.166; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_478903_0_0_12; -.
DR   OrthoDB; 355118at2; -.
DR   Proteomes; UP000008212; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:TreeGrafter.
DR   GO; GO:0006935; P:chemotaxis; IEA:TreeGrafter.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
PE   3: Inferred from homology;
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008212};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        169..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          345..552
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          325..405
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   552 AA;  60877 MW;  9D23AE3C64787CF0 CRC64;
     MKNYIKIVFA LCGIALAIGI GGAAFLIAAK PSSDFQLKTD YLLEYRFYLA SLKADMYRTA
     SKDGEFSVQN LKAKIKETVN SFENLKKLSA ADKSDSNLRF AYNDYESSND KLFKSIEVWR
     QEFELTGDSS AKTFMPVLKE FDAVQNSFER LKKEYKDGFT KQEKKSKTFA VLLIVLAWGI
     GVFLTWFVSS VIYKLYIERE RAKKAKLRLH VGPKTEVQRS SSDGPADKIL SVQSPRLSST
     SVSNTLMNTD SISDTSVNAF SVSTAPVNAA LLKTASISSA TISNATAEVP EKSLLQPAMV
     QGSYAETAPV RIGESNISIE SSPVYLKLQN DYKELKEMSD ELNGAYNELQ AKYSELGSSY
     KELQESLKQG DEKKAEKCET VKVFLTDIQM EAAEAQEDAQ AAQELVDTFQ GGHKLFKSTY
     EKIVHINQSI ADIQEMAEVI AGIAEQTKML SMNAAIEAAH AGDAGKGFAV VAEELGRLAT
     ASVESSAGIG KTVIEVVKNI SFMAKSSEDL DKAFNDINIK TNQVYTTVMN FSDRMIQTYQ
     KTDNVLRGLD TI
//