ID   Q72DP0_NITV2            Unreviewed;       379 AA.
AC   Q72DP0;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   04-NOV-2026, entry version 120.
DE   SubName: Full=Phosphonopyruvate decarboxylase-related protein {ECO:0000313|EMBL:AAS95369.1};
DE            EC=4.1.1.- {ECO:0000313|EMBL:AAS95369.1};
GN   OrderedLocusNames=DVU_0889 {ECO:0000313|EMBL:AAS95369.1};
OS   Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 /
OS   NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris).
OC   Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfovibrionia;
OC   Desulfovibrionales; Desulfovibrionaceae; Nitratidesulfovibrio.
OX   NCBI_TaxID=882 {ECO:0000313|EMBL:AAS95369.1, ECO:0000313|Proteomes:UP000002194};
RN   [1] {ECO:0000313|EMBL:AAS95369.1, ECO:0000313|Proteomes:UP000002194}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough
RC   {ECO:0000313|Proteomes:UP000002194};
RX   PubMed=15077118; DOI=10.1038/nbt959;
RA   Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA   Kolonay J.F., Eisen J.A., Ward N., Methe B., Brinkac L.M., Daugherty S.C.,
RA   Deboy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C.,
RA   Sullivan S.A., Fouts D., Haft D.H., Selengut J., Peterson J.D.,
RA   Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M.,
RA   Tran K., Khouri H., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D.,
RA   Voordouw G., Fraser C.M.;
RT   "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT   Desulfovibrio vulgaris Hildenborough.";
RL   Nat. Biotechnol. 22:554-559(2004).
CC   -!- FUNCTION: Catalyzes the interconversion of 2-phosphoglycerate and 3-
CC       phosphoglycerate. {ECO:0000256|ARBA:ARBA00002315}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate;
CC         Xref=Rhea:RHEA:15901, ChEBI:CHEBI:58272, ChEBI:CHEBI:58289;
CC         EC=5.4.2.12; Evidence={ECO:0000256|ARBA:ARBA00000370};
CC   -!- PATHWAY: Carbohydrate degradation. {ECO:0000256|ARBA:ARBA00004921}.
CC   -!- SIMILARITY: Belongs to the BPG-independent phosphoglycerate mutase
CC       family. A-PGAM subfamily. {ECO:0000256|ARBA:ARBA00005524}.
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DR   EMBL; AE017285; AAS95369.1; -; Genomic_DNA.
DR   SMR; Q72DP0; -.
DR   STRING; 882.DVU_0889; -.
DR   PaxDb; 882-DVU_0889; -.
DR   DNASU; 2794201; -.
DR   EnsemblBacteria; AAS95369; AAS95369; DVU_0889.
DR   KEGG; dvu:DVU_0889; -.
DR   PATRIC; fig|882.5.peg.832; -.
DR   eggNOG; COG3635; Bacteria.
DR   HOGENOM; CLU_830600_0_0_7; -.
DR   OMA; AADAPCK; -.
DR   OrthoDB; 9804453at2; -.
DR   PhylomeDB; Q72DP0; -.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 2.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR006124; Metalloenzyme.
DR   InterPro; IPR004456; Pglycerate_mutase_ApgM.
DR   PANTHER; PTHR31209:SF4; 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE; 1.
DR   PANTHER; PTHR31209; COFACTOR-INDEPENDENT PHOSPHOGLYCERATE MUTASE; 1.
DR   Pfam; PF01676; Metalloenzyme; 1.
DR   Pfam; PF10143; PhosphMutase; 1.
DR   PIRSF; PIRSF006392; IPGAM_arch; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004619; F:phosphoglycerate mutase activity; IEA:UniProtKB-EC.
DR   Proteomes; UP000002194; Chromosome.
DR   AlphaFoldDB; Q72DP0; -.
PE   3: Inferred from homology;
KW   Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW   Lyase {ECO:0000313|EMBL:AAS95369.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002194}.
FT   DOMAIN          4..346
FT                   /note="Metalloenzyme"
FT                   /evidence="ECO:0000259|Pfam:PF01676"
SQ   SEQUENCE   379 AA;  39110 MW;  1C5CC1F62BD78C5D CRC64;
     MMAKLVVCII DGMADPPPPA GGVTPLAAAH TPHCDTLARH SVAGLCHVIQ PEAVPGSEAG
     LSALLCCEAA ASIARGPVEA LAQGDPVAPH ETVWRLNLVS LGPRGNYYNP APLLDAATET
     AARKMLDRAL GTQGYSLLGG KGFRHLCAGT EPPVLRDGPQ DVCGMTPDTG QADLNSYCPR
     LARAMTEANV LFRRSRMDLA VWPWGAGTMP DLPGFAETTG QTGALAGGVP LARGLALALG
     MTAPSIAGAT GGIDTDLGAK TRAAIALAAG HDVVYLHVEA PDLHAHALDR VAKRRAIERI
     DAEVVGPLHM ALPDATLLIT CDHATDCATG RHMAIPVPFI LHKPDGPQDG IATFSEAASA
     RTGIRIDSAA TLVRLALAD
//