ID   Q6FMP8_CANGA            Unreviewed;       185 AA.
AC   Q6FMP8;
DT   19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   19-JUL-2004, sequence version 1.
DT   02-SEP-2026, entry version 119.
DE   RecName: Full=Guanylate kinase {ECO:0000256|ARBA:ARBA00016296};
DE            EC=2.7.4.8 {ECO:0000256|ARBA:ARBA00012961};
DE   AltName: Full=GMP kinase {ECO:0000256|ARBA:ARBA00030128};
GN   OrderedLocusNames=CAGL0K06281g {ECO:0000313|CGD:CAL0134671,
GN   ECO:0000313|EMBL:CAG61457.1};
OS   Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 /
OS   NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces.
OX   NCBI_TaxID=284593 {ECO:0000313|EMBL:CAG61457.1, ECO:0000313|Proteomes:UP000002428};
RN   [1] {ECO:0000313|EMBL:CAG61457.1, ECO:0000313|Proteomes:UP000002428}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS
RC   138 {ECO:0000313|Proteomes:UP000002428};
RX   PubMed=15229592; DOI=10.1038/nature02579;
RG   Genolevures;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L.,
RA   Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E.,
RA   Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SIMILARITY: Belongs to the guanylate kinase family.
CC       {ECO:0000256|ARBA:ARBA00005790}.
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DR   EMBL; CR380957; CAG61457.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6FMP8; -.
DR   FunCoup; Q6FMP8; 602.
DR   STRING; 284593.Q6FMP8; -.
DR   KEGG; cgr:2890461; -.
DR   CGD; CAL0134671; CAGL0K06281g.
DR   VEuPathDB; FungiDB:CAGL0K06281g; -.
DR   eggNOG; KOG0707; Eukaryota.
DR   HOGENOM; CLU_001715_0_4_1; -.
DR   InParanoid; Q6FMP8; -.
DR   OMA; NFITHEV; -.
DR   Proteomes; UP000002428; Chromosome K.
DR   GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR   GO; GO:0004385; F:GMP kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046711; P:GDP biosynthetic process; IEA:EnsemblFungi.
DR   CDD; cd00071; GMPK; 1.
DR   FunFam; 3.30.63.10:FF:000002; Guanylate kinase 1; 1.
DR   FunFam; 3.40.50.300:FF:000776; Guanylate kinase 2; 1.
DR   Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   HAMAP; MF_00328; Guanylate_kinase; 1.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR017665; Guanylate_kinase.
DR   InterPro; IPR020590; Guanylate_kinase_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR03263; guanyl_kin; 1.
DR   PANTHER; PTHR23117:SF13; GUANYLATE KINASE; 1.
DR   PANTHER; PTHR23117; GUANYLATE KINASE-RELATED; 1.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00100};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|PROSITE-
KW   ProRule:PRU00100};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00100}; Reference proteome {ECO:0000313|Proteomes:UP000002428};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU00100}.
FT   DOMAIN          2..183
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50052"
FT   BINDING         9..16
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00100"
SQ   SEQUENCE   185 AA;  20424 MW;  33EEB9A90789CA08 CRC64;
     MSRPIVISGP SGTGKSTLLK KLFAEFPDTF GFSVSSTTRS PRPGEVHGKD YNFVTVDEFK
     SMIDGEKFIE WAQFSGNYYG TTVDSVKAVI SSGKTCILDI DMQGVKAVKT KDLNARFLFV
     APPSMDDLKA RLQGRGTETD ESLQKRLAAA DAEMEYANSG AHDKIIVNDD LDKAYNELKQ
     FIFEN
//