ID   Q6AWC5_HUMAN            Unreviewed;       113 AA.
AC   Q6AWC5;
DT   13-SEP-2004, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2004, sequence version 1.
DT   02-SEP-2026, entry version 113.
DE   SubName: Full=Uncharacterized protein DKFZp686O0962 {ECO:0000313|EMBL:CAH10548.1};
DE   Flags: Fragment;
GN   Name=DKFZp686O0962 {ECO:0000313|EMBL:CAH10548.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CAH10548.1};
RN   [1] {ECO:0000313|EMBL:CAH10548.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Endometrium {ECO:0000313|EMBL:CAH10548.1};
RG   The German cDNA Consortium;
RA   Wambutt R., Heubner D., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G.,
RA   Han M., Wiemann S.;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the G-alpha family. G(i/o/t/z) subfamily.
CC       {ECO:0000256|ARBA:ARBA00006628}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01230}.
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DR   EMBL; BX647214; CAH10548.1; -; mRNA.
DR   AlphaFoldDB; Q6AWC5; -.
DR   IntAct; Q6AWC5; 1.
DR   PeptideAtlas; Q6AWC5; -.
DR   DNASU; 2775; -.
DR   ClinPGx; PA28771; -.
DR   DisGeNET; 2775; -.
DR   OrthoDB; 5817230at2759; -.
DR   BioGRID-ORCS; 2775; 11 hits in 1143 CRISPR screens.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   FunFam; 3.40.50.300:FF:002307; Guanine nucleotide-binding protein G(k) subunit alpha; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR001408; Gprotein_alpha_I.
DR   InterPro; IPR001019; Gprotein_alpha_su.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10218:SF363; G PROTEIN SUBUNIT ALPHA O1; 1.
DR   PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR   Pfam; PF00503; G-alpha; 1.
DR   PRINTS; PR00441; GPROTEINAI.
DR   SMART; SM00275; G_alpha; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51882; G_ALPHA; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|PIRSR:PIRSR601019-
KW   1}; Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|PIRSR:PIRSR601019-1};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU01230}.
FT   REGION          25..32
FT                   /note="G4 motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01230"
FT   REGION          83..88
FT                   /note="G5 motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01230"
FT   BINDING         29..32
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601019-1"
FT   BINDING         85
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601019-1"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAH10548.1"
SQ   SEQUENCE   113 AA;  12951 MW;  D471775FFC6B29F8 CRC64;
     NRMHESLKLF DSICNNKWFT DTSIILFLNK KDIFEEKIKK SPLTICFPEY TGPSAFTEAV
     AYIQAQYESK NKSAHKEIYT HVTCATDTNN IQFVFDAVTD VIIAKNLRGC GLY
//