ID   Q67LP6_SYMTH            Unreviewed;       413 AA.
AC   Q67LP6;
DT   11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   11-OCT-2004, sequence version 1.
DT   28-JAN-2026, entry version 93.
DE   SubName: Full=UDP-glucose:sterol glucosyltransferase {ECO:0000313|EMBL:BAD41400.1};
GN   OrderedLocusNames=STH2415 {ECO:0000313|EMBL:BAD41400.1};
OS   Symbiobacterium thermophilum (strain DSM 24528 / JCM 14929 / IAM 14863 /
OS   T).
OC   Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales;
OC   Symbiobacteriaceae; Symbiobacterium.
OX   NCBI_TaxID=292459 {ECO:0000313|EMBL:BAD41400.1, ECO:0000313|Proteomes:UP000000417};
RN   [1] {ECO:0000313|EMBL:BAD41400.1, ECO:0000313|Proteomes:UP000000417}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T / IAM 14863 {ECO:0000313|Proteomes:UP000000417};
RX   PubMed=15383646; DOI=10.1093/nar/gkh830;
RA   Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K.,
RA   Ikeda H., Hattori M., Beppu T.;
RT   "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium
RT   that depends on microbial commensalism.";
RL   Nucleic Acids Res. 32:4937-4944(2004).
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DR   EMBL; AP006840; BAD41400.1; -; Genomic_DNA.
DR   RefSeq; WP_011196538.1; NC_006177.1.
DR   AlphaFoldDB; Q67LP6; -.
DR   STRING; 292459.STH2415; -.
DR   KEGG; sth:STH2415; -.
DR   eggNOG; COG1819; Bacteria.
DR   HOGENOM; CLU_000537_8_0_9; -.
DR   OrthoDB; 9805366at2; -.
DR   Proteomes; UP000000417; Chromosome.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0033072; P:vancomycin biosynthetic process; IEA:UniProtKB-ARBA.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   FunFam; 3.40.50.2000:FF:000009; Sterol 3-beta-glucosyltransferase UGT80A2; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR010610; EryCIII-like_C.
DR   InterPro; IPR050426; Glycosyltransferase_28.
DR   InterPro; IPR004276; GlycoTrans_28_N.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR48050:SF13; STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2; 1.
DR   Pfam; PF06722; EryCIII-like_C; 1.
DR   Pfam; PF03033; Glyco_transf_28; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000417};
KW   Transferase {ECO:0000313|EMBL:BAD41400.1}.
FT   DOMAIN          3..129
FT                   /note="Glycosyltransferase family 28 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03033"
FT   DOMAIN          296..394
FT                   /note="Erythromycin biosynthesis protein CIII-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06722"
SQ   SEQUENCE   413 AA;  43640 MW;  95DEE5351E71AFBD CRC64;
     MKFVILATGT RGDVQPFVAL AQGLRAAGHE AVLAAPGSFE SFVRSHGVGF FPMGGDYAAL
     LESPEAQAAL RGNPVKMMQV VRQTVFPMMG RMLEDAWAAA QGADALVYHP KALAGAHLVE
     RLQVPCFIGA PVPVVVPTAA FPAPAFVSRD LGGFLNRLTY AAVRSGSRPF RGMINEWRRQ
     VLGLGPRREG EYVQGGRLIP VLHAFSPHVV PRPADWPPEA IVMGYWFPRR DEPWEPPAAL
     AAFLEEGPPP VYIGFGSVSG IDGDGSTRMA AEALARAGVR GVIATETGDA PVRLSDTVLA
     IPGAPHDWLF PRMAAVVHHG GAGTVAAGLA AGKPTLVCPA TTDQPFWGRV VHRLGVGPAP
     IPRRRLTAER LAAAIGTLTT DEDIQRRAAA LGEAIRAEDG VGRAVAEILR CSG
//