ID   Q65FN4_BACLD            Unreviewed;       661 AA.
AC   Q65FN4; Q62R44;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   02-SEP-2026, entry version 125.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAU24766.1};
GN   Name=mcpA {ECO:0000313|EMBL:AAU24766.1};
GN   OrderedLocusNames=BL02581 {ECO:0000313|EMBL:AAU24766.1};
OS   Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS   NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC   Bacteria; Bacillati; Bacillota; Bacilli; Caryophanales; Bacillaceae;
OC   Bacillus.
OX   NCBI_TaxID=279010 {ECO:0000313|EMBL:AAU24766.1, ECO:0000313|Proteomes:UP000000606};
RN   [1] {ECO:0000313|EMBL:AAU24766.1, ECO:0000313|Proteomes:UP000000606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB
RC   9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46
RC   {ECO:0000313|Proteomes:UP000000606};
RX   PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA   Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA   Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA   Rasmussen M.D., Andersen J.T., Jorgensen P.L., Larsen T.S., Sorokin A.,
RA   Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT   "Complete genome sequence of the industrial bacterium Bacillus
RT   licheniformis and comparisons with closely related Bacillus species.";
RL   Genome Biol. 5:R77.1-R77.12(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000002; AAU24766.1; -; Genomic_DNA.
DR   RefSeq; WP_003184749.1; NC_006270.3.
DR   AlphaFoldDB; Q65FN4; -.
DR   STRING; 279010.BL02581; -.
DR   GeneID; 92860115; -.
DR   KEGG; bld:BLi03296; -.
DR   KEGG; bli:BL02581; -.
DR   PATRIC; fig|279010.13.peg.3345; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   Proteomes; UP000000606; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016597; F:amino acid binding; IEA:UniProtKB-ARBA.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0043200; P:response to amino acid; IEA:UniProtKB-ARBA.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   FunFam; 3.30.450.20:FF:000048; Methyl-accepting chemotaxis protein; 1.
DR   FunFam; 1.10.287.950:FF:000001; Methyl-accepting chemotaxis sensory transducer; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   InterPro; IPR003122; Tar_rcpt_lig-bd.
DR   NCBIfam; NF051893; MCPTlpBBacil; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   PANTHER; PTHR32089:SF114; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SMART; SM00319; TarH; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000606};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        279..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          303..355
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          374..610
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   661 AA;  72144 MW;  5DCF32FFAF2B00F1 CRC64;
     MKKILDWLKR PSISKRLFFS FILVLTLPIL ALSYSAYQTA GSSLETEIMR SARDNVEQLN
     EIIDQNIGEK EEAVSFFSGL VNEKLYQEKE NASLVERLEQ YAKLNQDVEA IYTGSKDGKF
     IRYPAEKMAK GYNPADRDWY KQAVENKGKV IITNPYKTAS TGTMVITIAK QTEDGSGVVA
     VNMKIDELIK ATERVNIGKS GFAFISSNDK KYVAHPTIEA GTEGKGDWVG QMYGSEKGDF
     QYTFEGKEKK MAFTTNKLTG WKIGGTMFTD EISEAAQPVF HMAIIILAAA IVLGGILIYF
     IIRGISKPLS ELVSSAKSIS GGDLTQKIEV RSKDEFGQLG TSFNEMAESL RSLISVIQSS
     VDNVASSSEE LHASAAQTSK ATEHITMAIE QFSDGNESQK EKVEASSHQL NEMNNGLYDM
     SKTSAAITDA SLKSTEIAGK GEELVQKTVG QMNSIDRSVK QAEAVVKGLE AKSKDITSIL
     RVINGIADQT NLLALNAAIE AARAGESGRG FSVVAEEVRK LAAQSADSAK EIEHLIQEIV
     KEIDNSLNMF KSVNHEVQSG LRITDETETS FKTIYDMTND IAGKLQTMNA AVEQLTQGSR
     QVAGAVEEIA DVSRESSASI QDIAASAEEQ LASMEEISAS STTLAELAEE LRDLTQKFKI
     E
//