ID   Q63IX5_BURPS            Unreviewed;       521 AA.
AC   Q63IX5;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   02-SEP-2026, entry version 94.
DE   SubName: Full=Methyl-accepting chemotaxis transducer transmembrane protein {ECO:0000313|EMBL:CAH39419.1};
GN   OrderedLocusNames=BPSS1941 {ECO:0000313|EMBL:CAH39419.1};
OS   Burkholderia pseudomallei (strain K96243).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC   Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=272560 {ECO:0000313|EMBL:CAH39419.1, ECO:0000313|Proteomes:UP000000605};
RN   [1] {ECO:0000313|EMBL:CAH39419.1, ECO:0000313|Proteomes:UP000000605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K96243 {ECO:0000313|EMBL:CAH39419.1,
RC   ECO:0000313|Proteomes:UP000000605};
RX   PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA   Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.M., Atkins T.,
RA   Crossman L.C., Pitt T., Churcher C., Mungall K., Bentley S.D., Sebaihia M.,
RA   Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A., Brown N.F.,
RA   Challis G.L., Cherevach I., Chillingworth T., Cronin A., Crosset B.,
RA   Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z., Hauser H.,
RA   Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M., Simmonds M.,
RA   Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M., Whitehead S.,
RA   Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT   "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT   pseudomallei.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; BX571966; CAH39419.1; -; Genomic_DNA.
DR   RefSeq; WP_004524990.1; NC_006351.1.
DR   AlphaFoldDB; Q63IX5; -.
DR   STRING; 272560.BPSS1941; -.
DR   GeneID; 93064168; -.
DR   KEGG; bps:BPSS1941; -.
DR   PATRIC; fig|272560.51.peg.5429; -.
DR   eggNOG; COG0840; Bacteria.
DR   Proteomes; UP000000605; Chromosome 2.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd11386; MCP_signal; 1.
DR   FunFam; 1.10.287.950:FF:000001; Methyl-accepting chemotaxis sensory transducer; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR033480; sCache_2.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF17200; sCache_2; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM01049; Cache_2; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000605};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          272..501
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          301..328
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   521 AA;  55667 MW;  3FB42B3CA616799E CRC64;
     MPTLSFRQKL WLPLVISLIA LLLVSISSAW LSYQTRMEER RNDLTNVAHV GLSIVREYAA
     LAQRGVLTDA QARKEALERL RSVRYGSDGY FIVIDSSPRM IMHPIKPDTV GKDLRHVADA
     DGRHHYLTFA SVAQSPQGGF VDYVFAHPNA HPAKAVDKLG YVIRYAPWDW IISTGAYIDD
     IQAAFAKSLC LSAGVFALLA ALLALSVVYT NRGIERMIGG DPRIAAHMAG VIASGDLATP
     FATRREDRSS LMFAISQMRD ALANAVAQIR ASAGYVATTA GEIADSNMDL SSHTECQATA
     LQQAASSMQR LTERVRDTAD RARAASELAG SAARITDRGG DMVVRVVAAM NDIRAESRKM
     VDIIGVIEGI AFQTNILALN AAVEAARAGN EGRGFAVVAS EVRVLAQRSA SAAKDIRALI
     GRAAERVGNG AELVEATGAT IGEAQHAICR VTGIVQDIAA AATDQSQGLE QINAAVSQMD
     SVTRRNATLV EHAAIAAQSL NEQSRCLQDA VAAFRTEALG C
//