##gff-version 3 Q63959 UniProtKB Chain 1 769 . . . ID=PRO_0000054056;Note=Voltage-gated potassium channel KCNC3 Q63959 UniProtKB Topological domain 1 291 . . . Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q63959 UniProtKB Transmembrane 292 310 . . . Note=Helical%3B Name%3DSegment S1;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Transmembrane 352 371 . . . Note=Helical%3B Name%3DSegment S2;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Topological domain 372 380 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Transmembrane 381 399 . . . Note=Helical%3B Name%3DSegment S3;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Transmembrane 413 435 . . . Note=Helical%3B Voltage-sensor%3B Name%3DSegment S4;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Topological domain 436 448 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Transmembrane 449 470 . . . Note=Helical%3B Name%3DSegment S5;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Transmembrane 519 540 . . . Note=Helical%3B Name%3DSegment S6;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Topological domain 541 769 . . . Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Region 1 80 . . . Note=Important for normal N-type inactivation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18539595;Dbxref=PMID:18539595 Q63959 UniProtKB Region 8 66 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q63959 UniProtKB Region 202 231 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q63959 UniProtKB Region 557 627 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q63959 UniProtKB Region 679 701 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q63959 UniProtKB Region 746 769 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q63959 UniProtKB Motif 504 509 . . . Note=Selectivity filter;Ontology_term=ECO:0000250;evidence=ECO:0000250 Q63959 UniProtKB Compositional bias 22 41 . . . Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q63959 UniProtKB Compositional bias 211 222 . . . Note=Low complexity;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite Q63959 UniProtKB Binding site 159 159 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Binding site 165 165 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Binding site 186 186 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Binding site 187 187 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Binding site 504 504 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Binding site 505 505 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Binding site 506 506 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Binding site 507 507 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P48547 Q63959 UniProtKB Modified residue 626 626 . . . Note=Omega-N-methylarginine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:24129315;Dbxref=PMID:24129315 Q63959 UniProtKB Modified residue 687 687 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 Q63959 UniProtKB Modified residue 692 692 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 Q63959 UniProtKB Modified residue 731 731 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 Q63959 UniProtKB Modified residue 734 734 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 Q63959 UniProtKB Modified residue 742 742 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 Q63959 UniProtKB Modified residue 750 750 . . . Note=Phosphothreonine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 Q63959 UniProtKB Modified residue 754 754 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 Q63959 UniProtKB Glycosylation 321 321 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Glycosylation 337 337 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Glycosylation 484 484 . . . Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 Q63959 UniProtKB Mutagenesis 424 424 . . . Note=Loss of channel activity. Functions as dominant negative mutation that impairs function of wild-type channel subunits. Causes impaired Purkinje cell dendrite growth and premature death of cerebellar Purkinje cells. R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:24218544;Dbxref=PMID:24218544 Q63959 UniProtKB Mutagenesis 593 593 . . . Note=No effect on voltage-dependent channel opening or current amplitude%2C but decreased rate of inactivation during prolonged depolarization. G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26997484;Dbxref=PMID:26997484 Q63959 UniProtKB Sequence conflict 13 13 . . . Note=R->C;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q63959 UniProtKB Sequence conflict 51 62 . . . Note=AASPAGAPLSCG->GPSPGVPAFLR;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q63959 UniProtKB Sequence conflict 257 267 . . . Note=GPAGGAGGAGG->DLPGARAAGA;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q63959 UniProtKB Sequence conflict 258 259 . . . Note=PA->LP;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q63959 UniProtKB Sequence conflict 522 522 . . . Note=A->G;Ontology_term=ECO:0000305;evidence=ECO:0000305 Q63959 UniProtKB Sequence conflict 660 660 . . . Note=A->AV;Ontology_term=ECO:0000305;evidence=ECO:0000305