ID   Q5TML0_ANOGA            Unreviewed;       428 AA.
AC   Q5TML0;
DT   07-DEC-2004, integrated into UniProtKB/TrEMBL.
DT   07-DEC-2004, sequence version 1.
DT   04-NOV-2026, entry version 122.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AGAP011723-PA};
GN   Name=3291416 {ECO:0000313|EnsemblMetazoa:AGAP011723-PA};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Altocrustacea; Allotriocarida;
OC   Hexapoda; Insecta; Pterygota; Neoptera; Eumetabola; Endopterygota;
OC   Aparaglossata; Panorpida; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|EnsemblMetazoa:AGAP011723-PA, ECO:0000313|Proteomes:UP000007062};
RN   [1] {ECO:0000313|EnsemblMetazoa:AGAP011723-PA, ECO:0000313|Proteomes:UP000007062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP011723-PA,
RC   ECO:0000313|Proteomes:UP000007062};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R.,
RA   Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z.,
RA   Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA   Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA   Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA   Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V.,
RA   Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA   Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA   Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA   Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I.,
RA   Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A.,
RA   McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D.,
RA   O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA   Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA   Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A.,
RA   Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A.,
RA   Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA   Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA   Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA   Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
RN   [2] {ECO:0000313|EnsemblMetazoa:AGAP011723-PA, ECO:0000313|Proteomes:UP000007062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP011723-PA,
RC   ECO:0000313|Proteomes:UP000007062};
RX   PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA   Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT   "The Anopheles gambiae genome: an update.";
RL   Trends Parasitol. 20:49-52(2004).
RN   [3] {ECO:0000313|EnsemblMetazoa:AGAP011723-PA}
RP   IDENTIFICATION.
RC   STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP011723-PA};
RG   EnsemblMetazoa;
RL   Submitted (JAN-2021) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000256|ARBA:ARBA00007274}.
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DR   EMBL; AAAB01008986; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q5TML0; -.
DR   STRING; 7165.Q5TML0; -.
DR   PaxDb; 7165-Q5TML0; -.
DR   EnsemblMetazoa; AGAP011723-RA; AGAP011723-PA; AGAP011723.
DR   KEGG; aga:3291416; -.
DR   VEuPathDB; VectorBase:AGAMI1_011043; -.
DR   VEuPathDB; VectorBase:AGAP011723; -.
DR   eggNOG; KOG1460; Eukaryota.
DR   HOGENOM; CLU_029499_3_0_1; -.
DR   OMA; AAAMVMW; -.
DR   Proteomes; UP000007062; Chromosome 3L.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   CDD; cd06428; M1P_guanylylT_A_like_N; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   Gene3D; 3.90.550.10; Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A; 1.
DR   InterPro; IPR056729; GMPPB_C.
DR   InterPro; IPR050486; Mannose-1P_guanyltransferase.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR22572; SUGAR-1-PHOSPHATE GUANYL TRANSFERASE; 1.
DR   Pfam; PF25087; GMPPB_C; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007062}.
FT   DOMAIN          3..195
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
FT   DOMAIN          290..427
FT                   /note="Mannose-1-phosphate guanyltransferase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF25087"
SQ   SEQUENCE   428 AA;  47261 MW;  7E3A4D1999B81357 CRC64;
     MLKAVILIGG PEKGTRFRPL SLDTPKPLFP VAGKPIIQHH VESCVRIKEL KEILILGFYP
     ATQMQQFVSN MQNLYDVNIR YLQEFTALGT AGGMYHFRDQ IRSGNPGAFF VLNGDVCADF
     PLQELYDFHR SKNEKALVSI MGTEATRQQA VHYGCLVLGK DEEVTHYVEK PRSYLSTLIN
     CGVYVCSMDI FAKMGAVFHS KQQDYSMLNN GNGKDSGHIQ WEQEILTPLA GTGKLYALPV
     NNWWSQIKTA GSAIYANRHY LALYKNAHPE RLASAGLKTE NDNANLVCNI VPDVHIHPTA
     SVHPTATLGP NVSIGPGVVI GPGVRVRESI ILENAVIKDH SLVLHSIVGR GSQIGMWARV
     EGTPSDPDPN KPFAKMENPP LFNTDGRLNP SITILGYAVS VPSEMIVLNS IVLPHKELSR
     SFKNEIIL
//