ID   Q51183_NEIME            Unreviewed;        58 AA.
AC   Q51183;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   02-APR-2025, entry version 74.
DE   SubName: Full=Class 1 outer membrane protein variable region 2 {ECO:0000313|EMBL:CAA78633.1};
DE   Flags: Fragment;
GN   Name=porA {ECO:0000313|EMBL:CAA78633.1};
OS   Neisseria meningitidis.
OC   Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC   Neisseriaceae; Neisseria.
OX   NCBI_TaxID=487 {ECO:0000313|EMBL:CAA78633.1};
RN   [1] {ECO:0000313|EMBL:CAA78633.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=L2502 {ECO:0000313|EMBL:CAA78633.1};
RX   PubMed=2503673; DOI=10.1111/j.1365-2958.1989.tb01802.x;
RA   Barlow A.K., Heckels J.E., Clarke I.N.;
RT   "The class 1 outer membrane protein of Neisseria meningitidis: gene
RT   sequence and structural and immunological similarities to gonococcal
RT   porins.";
RL   Mol. Microbiol. 3:131-139(1989).
RN   [2] {ECO:0000313|EMBL:CAA78633.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=L2502 {ECO:0000313|EMBL:CAA78633.1};
RX   PubMed=1693651; DOI=10.1084/jem.171.6.1871;
RA   McGuinnes B., Barlow A.K., Clarke I.N., Farley J.E., Anilionis A.,
RA   Poolman J.T., Heckels J.E.;
RT   "Deduced amino acid sequences of class 1 protein (PorA) from three strains
RT   of Neisseria meningitidis. Synthetic peptides define the epitopes
RT   responsible for serosubtype specificity.";
RL   J. Exp. Med. 171:1871-1882(1990).
RN   [3] {ECO:0000313|EMBL:CAA78633.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=L2502 {ECO:0000313|EMBL:CAA78633.1};
RA   McGuinness B.T., Lambden P.R., Heckels J.E.;
RT   "Class 1 outer membrane protein of Neisseria meningitidis: Epitope analysis
RT   of the antigenic diversity between strains, implications for subtype
RT   definition and molecular epidemiology.";
RL   Submitted (AUG-1992) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0007829|PDB:2BRR}
RP   X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 16-26.
RX   PubMed=16038932; DOI=10.1016/j.jmb.2005.06.061;
RA   Oomen C.J., Hoogerhout P., Kuipers B., Vidarsson G., van Alphen L.,
RA   Gros P.;
RT   "Crystal structure of an Anti-meningococcal subtype P1.4 PorA antibody
RT   provides basis for peptide-vaccine design.";
RL   J. Mol. Biol. 351:1070-1080(2005).
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DR   EMBL; Z14266; CAA78633.1; -; Genomic_DNA.
DR   PIR; S26108; S26108.
DR   PDB; 2BRR; X-ray; 1.95 A; P=16-26.
DR   AlphaFoldDB; Q51183; -.
DR   SMR; Q51183; -.
DR   ABCD; Q51183; 1 sequenced antibody.
DR   EvolutionaryTrace; Q51183; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:InterPro.
DR   GO; GO:0015288; F:porin activity; IEA:InterPro.
DR   GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:InterPro.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   Pfam; PF00267; Porin_1; 1.
DR   PDBsum; 2BRR; -.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:2BRR}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAA78633.1"
FT   NON_TER         58
FT                   /evidence="ECO:0000313|EMBL:CAA78633.1"
SQ   SEQUENCE   58 AA;  6220 MW;  6FF363BF7A0C06A5 CRC64;
     QFVPIQNSKS AYTPAHVVVN NKVATHVPAV VGKPGSDVYY AGLNYKNGGF AGNYAFKY
//