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<entry dataset="TrEMBL" created="2005-06-07" modified="2026-11-04" version="114" xmlns="http://uniprot.org/uniprot">
  <accession>Q4ZQT9</accession>
  <name>Q4ZQT9_PSEU2</name>
  <protein>
    <submittedName>
      <fullName evidence="4">Response regulator receiver:ATP-binding region, ATPase-like:Stage II sporulation E</fullName>
    </submittedName>
  </protein>
  <gene>
    <name evidence="4" type="ordered locus">Psyr_3451</name>
  </gene>
  <organism evidence="4 5">
    <name type="scientific">Pseudomonas syringae pv. syringae (strain B728a)</name>
    <dbReference type="NCBI Taxonomy" id="205918"/>
    <lineage>
      <taxon>Bacteria</taxon>
      <taxon>Pseudomonadati</taxon>
      <taxon>Pseudomonadota</taxon>
      <taxon>Gammaproteobacteria</taxon>
      <taxon>Pseudomonadales</taxon>
      <taxon>Pseudomonadaceae</taxon>
      <taxon>Pseudomonas</taxon>
      <taxon>Pseudomonas syringae</taxon>
    </lineage>
  </organism>
  <reference evidence="4 5" key="1">
    <citation type="journal article" date="2005" name="Proc. Natl. Acad. Sci. U.S.A." volume="102" first="11064" last="11069">
      <title>Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000.</title>
      <authorList>
        <person name="Feil H."/>
        <person name="Feil W.S."/>
        <person name="Chain P."/>
        <person name="Larimer F."/>
        <person name="Dibartolo G."/>
        <person name="Copeland A."/>
        <person name="Lykidis A."/>
        <person name="Trong S."/>
        <person name="Nolan M."/>
        <person name="Goltsman E."/>
        <person name="Thiel J."/>
        <person name="Malfatti S."/>
        <person name="Loper J.E."/>
        <person name="Lapidus A."/>
        <person name="Detter J.C."/>
        <person name="Land M."/>
        <person name="Richardson P.M."/>
        <person name="Kyrpides N.C."/>
        <person name="Ivanova N."/>
        <person name="Lindow S.E."/>
      </authorList>
      <dbReference type="PubMed" id="16043691"/>
      <dbReference type="DOI" id="10.1073/pnas.0504930102"/>
    </citation>
    <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    <source>
      <strain evidence="4 5">B728a</strain>
    </source>
  </reference>
  <dbReference type="EMBL" id="CP000075">
    <property type="protein sequence ID" value="AAY38483.1"/>
    <property type="molecule type" value="Genomic_DNA"/>
  </dbReference>
  <dbReference type="RefSeq" id="WP_011268439.1">
    <property type="nucleotide sequence ID" value="NC_007005.1"/>
  </dbReference>
  <dbReference type="AlphaFoldDB" id="Q4ZQT9"/>
  <dbReference type="STRING" id="205918.Psyr_3451"/>
  <dbReference type="KEGG" id="psb:Psyr_3451"/>
  <dbReference type="PATRIC" id="fig|205918.7.peg.3536"/>
  <dbReference type="eggNOG" id="COG2208">
    <property type="taxonomic scope" value="Bacteria"/>
  </dbReference>
  <dbReference type="eggNOG" id="COG3437">
    <property type="taxonomic scope" value="Bacteria"/>
  </dbReference>
  <dbReference type="HOGENOM" id="CLU_000445_43_7_6"/>
  <dbReference type="OMA" id="ACQKPSG"/>
  <dbReference type="OrthoDB" id="9811749at2"/>
  <dbReference type="Proteomes" id="UP000000426">
    <property type="component" value="Chromosome"/>
  </dbReference>
  <dbReference type="GO" id="GO:0016791">
    <property type="term" value="F:phosphatase activity"/>
    <property type="project" value="TreeGrafter"/>
  </dbReference>
  <dbReference type="GO" id="GO:0000160">
    <property type="term" value="P:phosphorelay signal transduction system"/>
    <property type="project" value="InterPro"/>
  </dbReference>
  <dbReference type="CDD" id="cd16936">
    <property type="entry name" value="HATPase_RsbW-like"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="Gene3D" id="3.40.50.2300">
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="Gene3D" id="3.30.565.10">
    <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="Gene3D" id="3.60.40.10">
    <property type="entry name" value="PPM-type phosphatase domain"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="InterPro" id="IPR052016">
    <property type="entry name" value="Bact_Sigma-Reg"/>
  </dbReference>
  <dbReference type="InterPro" id="IPR011006">
    <property type="entry name" value="CheY-like_sf"/>
  </dbReference>
  <dbReference type="InterPro" id="IPR036890">
    <property type="entry name" value="HATPase_C_sf"/>
  </dbReference>
  <dbReference type="InterPro" id="IPR036457">
    <property type="entry name" value="PPM-type-like_dom_sf"/>
  </dbReference>
  <dbReference type="InterPro" id="IPR001932">
    <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
  </dbReference>
  <dbReference type="InterPro" id="IPR001789">
    <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
  </dbReference>
  <dbReference type="PANTHER" id="PTHR43156:SF2">
    <property type="entry name" value="STAGE II SPORULATION PROTEIN E"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="PANTHER" id="PTHR43156">
    <property type="entry name" value="STAGE II SPORULATION PROTEIN E-RELATED"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="Pfam" id="PF00072">
    <property type="entry name" value="Response_reg"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="Pfam" id="PF07228">
    <property type="entry name" value="SpoIIE"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="SMART" id="SM00331">
    <property type="entry name" value="PP2C_SIG"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="SMART" id="SM00448">
    <property type="entry name" value="REC"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="SUPFAM" id="SSF55874">
    <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="SUPFAM" id="SSF52172">
    <property type="entry name" value="CheY-like"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="SUPFAM" id="SSF81606">
    <property type="entry name" value="PP2C-like"/>
    <property type="match status" value="1"/>
  </dbReference>
  <dbReference type="PROSITE" id="PS50110">
    <property type="entry name" value="RESPONSE_REGULATORY"/>
    <property type="match status" value="1"/>
  </dbReference>
  <proteinExistence type="predicted"/>
  <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
  <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
  <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
  <feature type="domain" description="Response regulatory" evidence="3">
    <location>
      <begin position="9"/>
      <end position="125"/>
    </location>
  </feature>
  <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
    <location>
      <position position="58"/>
    </location>
  </feature>
  <evidence type="ECO:0000256" key="1">
    <source>
      <dbReference type="ARBA" id="ARBA00022801"/>
    </source>
  </evidence>
  <evidence type="ECO:0000256" key="2">
    <source>
      <dbReference type="PROSITE-ProRule" id="PRU00169"/>
    </source>
  </evidence>
  <evidence type="ECO:0000259" key="3">
    <source>
      <dbReference type="PROSITE" id="PS50110"/>
    </source>
  </evidence>
  <evidence type="ECO:0000313" key="4">
    <source>
      <dbReference type="EMBL" id="AAY38483.1"/>
    </source>
  </evidence>
  <evidence type="ECO:0000313" key="5">
    <source>
      <dbReference type="Proteomes" id="UP000000426"/>
    </source>
  </evidence>
  <sequence length="568" mass="62029" checksum="9E43C1DC5EBC811B" modified="2005-06-07" version="1">MQPAPNKLCILIADDSTSDRLLLSTIVARQGHRVLSAGNGVEAVAIFEAESPQLILMDAMMPVMDGFEAARRIKAMAGESLVPIIFLTSLTEGEALARCLDAGGDDFMSKPYNPLVLAAKLNAMNRLRVLHETVRQQRDQIARHHEYLLNEQRVAKAVFDQIAHAGCLGASNIRYLQSPYALFNGDLMLAAYTPAGHMQVLLGDFTGHGLPAAVGAMPLAEVFYGMTAKGYGLVEILREMNAKLKRILPVDMFCCATLLCINLPQRQVEVWSGGLPDGYLLRGAQGEHVPLASNHLPLGVLSVDAFDARTDVYPLAPGDRIFLLSDGVLDTSNSQEELFGAQRLRQVLSANREPQLLIEEILEALNEFGGKARDDVSLLEVSAVEAPLQSLPAMMYSDSGASSPLDWSASFEFRASTLKRFNPLPYVLQLLLEVHGLRDQGAALHMVLGELYSNALEHGVLGLDSALKHDAAGFALYYQQRAERLDRLQSGFIRMTLQVETVAQGGRLTLGVEDSGQGFDVEKTRTLTPAGNELYGRGLHLVCELSREARWSRDGRTACVEFSWEGVA</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>